Circadian rhythm and disease: Relationship, new insights, and future perspectives

Association of PER2 gene single nucleotide polymorphisms with genetic susceptibility to systemic lupus erythematosus

(2021) Yi-Lin Dan et al.   LUPUS

Clocks, cancer, and chronochemotherapy

(2021) Aziz Sancar et al.   SCIENCE

Small-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases

(2021) Rodrigo F.N. Ribeiro et al.   DRUG DISCOVERY TODAY

Correlation between circadian rhythm related genes, type 2 diabetes, and cancer: Insights from metanalysis of transcriptomics data

(2021) Thaysa Kelly Barbosa Vieira et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The effects of bright light therapy on depression and sleep disturbances in patients with Parkinson's disease: A systematic review and meta-analysis of randomized controlled trials

(2021) Fabin Lin et al.   SLEEP MEDICINE

Disrupted Expression of Circadian Clock Genes in Patients with Bronchial Asthma

(2021) Hung-Chen Chen et al.   Journal of Asthma and Allergy

Circadian clock genes as promising therapeutic targets for autoimmune diseases

(2021) Kun Xiang et al.   AUTOIMMUNITY REVIEWS

Circadian clock, carcinogenesis, chronochemotherapy connections

(2021) Yanyan Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the link between chronobiology and drug delivery: effects on cancer therapy

(2021) Tânia Albuquerque et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Effect of Light Therapy on Cancer-related Fatigue: A Systematic Review and Meta-Analysis

(2021) Panpan Xiao et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

The endogenous circadian system worsens asthma at night independent of sleep and other daily behavioral or environmental cycles

(2021) Frank A. J. L. Scheer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The efficacy of combined bright light and melatonin therapies on sleep and circadian outcomes: A systematic review

(2021) Daniel Chih Yung Cheng et al.   SLEEP MEDICINE REVIEWS

Structure-based design and classifications of small molecules regulating the circadian rhythm period

(2021) Seref Gul et al.   Scientific Reports

Circadian clock and cell cycle: Cancer and chronotherapy

(2021) Jing Yao et al.   ACTA HISTOCHEMICA

Time spent in outdoor light is associated with mood, sleep, and circadian rhythm-related outcomes: A cross-sectional and longitudinal study in over 400,000 UK Biobank participants

(2021) Angus C. Burns et al.   JOURNAL OF AFFECTIVE DISORDERS

The role of circadian rhythm in choroid plexus functions

(2021) Telma Quintela et al.   PROGRESS IN NEUROBIOLOGY

Identification of novel small molecules targeting core clock proteins to regulate circadian rhythm

(2021) Ibrahim Halil Kavakli et al.   Current Opinion in Chemical Engineering

Use of Natural Products in Asthma Treatment

(2020) Lucas Amaral-Machado et al.   Evidence-based Complementary and Alternative Medicine

Food as a circadian time cue — evidence from human studies

(2020) Philip Lewis et al.   Nature Reviews Endocrinology

T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy

(2020) Amir Sharabi et al.   Nature Reviews Rheumatology

Effects of acute sleep loss on diurnal plasma dynamics of CNS health biomarkers in young men

(2020) Christian Benedict et al.   NEUROLOGY

Interleukin-2 chronotherapy for metastatic renal cell carcinoma: Results of a phase I-II study

(2020) Giovanni Lo Re et al.   CYTOKINE

Antidepressant Light Therapy for Bipolar Patients: a Meta-Analyses

(2020) Sara Dallaspezia et al.   JOURNAL OF AFFECTIVE DISORDERS

Sex‐dependent least toxic timing of irinotecan combined with chronomodulated chemotherapy for metastatic colorectal cancer: Randomized multicenter EORTC 05011 trial

(2020) Pasquale F. Innominato et al.   Cancer Medicine

Chronotherapy of Hypertension with Angiotensin Receptor Blockers–A Meta-Analysis of Blood Pressure Measured by Ambulatory Blood Pressure Monitoring in Randomized Trials

(2020) Di Zhao et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

A molecular circadian clock operates in the parathyroid gland and is disturbed in chronic kidney disease associated bone and mineral disorder.

(2020) Søren Egstrand et al.   KIDNEY INTERNATIONAL

Perturbation of the circadian clock and pathogenesis of NAFLD

(2020) Atish Mukherji et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice

(2020) Eva Hadadi et al.   Nature Communications

Association of Circadian Abnormalities in Older Adults With an Increased Risk of Developing Parkinson Disease

(2020) Yue Leng et al.   JAMA Neurology

Association Between Night-Shift Work and Cancer Risk: Updated Systematic Review and Meta-Analysis

(2020) Aishe Dun et al.   Frontiers in Oncology

Feeding Rhythms and the Circadian Regulation of Metabolism

(2020) Lauren Pickel et al.   Frontiers in Nutrition

The Future of Shift Work: Circadian Biology Meets Personalised Medicine and Behavioural Science

(2020) Gregory D. M. Potter et al.   Frontiers in Nutrition

Effect of time of day of recreational and household physical activity on prostate and breast cancer risk ( MCC‐Spain study)

(2020) Jakob Weitzer et al.   INTERNATIONAL JOURNAL OF CANCER

Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation

(2020) I. Aiello et al.   Science Advances

Therapeutics on the clock: Circadian medicine in the treatment of chronic inflammatory diseases

(2020) Haritha Jacob et al.   BIOCHEMICAL PHARMACOLOGY

Clock Genes, Inflammation and the Immune System—Implications for Diabetes, Obesity and Neurodegenerative Diseases

(2020) Elaine Vieira et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Efficacy of light therapy for a college student sample with non-seasonal subthreshold depression: An RCT study

(2020) Lijun Jiang et al.   JOURNAL OF AFFECTIVE DISORDERS

The circadian machinery links metabolic disorders and depression: A review of pathways, proteins and potential pharmacological interventions

(2020) Eleni Pitsillou et al.   LIFE SCIENCES

Human circadian phase–response curves for exercise

(2019) Shawn D. Youngstedt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals

(2019) Dirk Jan Stenvers et al.   DIABETOLOGIA

Phase 1 Open-Label, Multicenter Study of First-in-Class RORγ Agonist LYC-55716: Safety, Tolerability, and Preliminary Evidence of Antitumor Activity

(2019) Devalingam Mahalingam et al.   CLINICAL CANCER RESEARCH

Gestational jet lag predisposes to later-life skeletal and cardiac disease

(2019) Inês Chaves et al.   CHRONOBIOLOGY INTERNATIONAL

Shift Work Patterns, Chronotype, and Epithelial Ovarian Cancer Risk

(2019) Lisa Leung et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A novel comprehensive paradigm for the etiopathogenesis of multiple sclerosis: therapeutic approaches and future perspectives on its treatment

(2019) Francesco Gasperoni et al.   AMINO ACIDS

The importance of determining circadian parameters in pharmacological studies

(2019) Laetitia Gaspar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time

(2019) Priya Crosby et al.   CELL

The role of sleep deprivation and circadian rhythm disruption as risk factors of Alzheimer’s disease

(2019) Hao Wu et al.   FRONTIERS IN NEUROENDOCRINOLOGY

In vivo molecular chronotyping, circadian misalignment, and high rates of depression in young adults

(2019) Chi Nguyen et al.   JOURNAL OF AFFECTIVE DISORDERS

MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle

(2019) Brian A Hodge et al.   eLife

Circadian rhythm of exhaled biomarkers in health and asthma

(2019) Maxim Wilkinson et al.   EUROPEAN RESPIRATORY JOURNAL

Night-shift work, circadian and melatonin pathway related genes and their interaction on breast cancer risk: evidence from a case-control study in Korean women

(2019) Thu-Thi Pham et al.   Scientific Reports

Rapid suppression of bone formation marker in response to sleep restriction and circadian disruption in men

(2019) C.M. Swanson et al.   OSTEOPOROSIS INTERNATIONAL

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock

(2019) Zhen Dong et al.   Cancer Discovery

Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial

(2019) Ramón C Hermida et al.   EUROPEAN HEART JOURNAL

Impact of Circadian Disruption on Cardiovascular Function and Disease

(2019) Sarah L. Chellappa et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Circadian rhythms in adaptive immunity

(2019) Polly Downton et al.   IMMUNOLOGY

The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus

(2019) Michelle D. Catalina et al.   JOURNAL OF AUTOIMMUNITY

Molecular Connections Between Circadian Clocks and Mood-related Behaviors

(2019) Urs Albrecht   JOURNAL OF MOLECULAR BIOLOGY

Light therapy with boxes or glasses to counteract effects of acute sleep deprivation

(2019) Henri Comtet et al.   Scientific Reports

Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial

(2018) Dorothy K. Sit et al.   AMERICAN JOURNAL OF PSYCHIATRY

Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes

(2018) Elizabeth F. Sutton et al.   Cell Metabolism

Differential effects of the circadian system and circadian misalignment on insulin sensitivity and insulin secretion in humans

(2018) Jingyi Qian et al.   DIABETES OBESITY & METABOLISM

Hypertension: New perspective on its definition and clinical management by bedtime therapy substantially reduces cardiovascular disease risk

(2018) Ramón C. Hermida et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Night shift work and breast cancer: a pooled analysis of population-based case–control studies with complete work history

(2018) Emilie Cordina-Duverger et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Rotating Night Shift work and Colorectal Cancer Risk in the Nurses' Health Studies

(2018) Kyriaki Papantoniou et al.   INTERNATIONAL JOURNAL OF CANCER

Role of the circadian system in cardiovascular disease

(2018) Saurabh S. Thosar et al.   JOURNAL OF CLINICAL INVESTIGATION

Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study

(2018) David Montaigne et al.   LANCET

Less than 7 hours of sleep per night is associated with transitioning to systemic lupus erythematosus

(2018) K A Young et al.   LUPUS

The importance of the circadian system & sleep for bone health

(2018) Christine M. Swanson et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Association of circadian rhythm genes ARNTL/BMAL1 and CLOCK with multiple sclerosis

(2018) Polona Lavtar et al.   PLoS One

Night-shift work and breast and prostate cancer risk: updating the evidence from epidemiological studies

(2018) E. Salamanca-Fernández   Anales del Sistema Sanitario De Navarra

Depressive mood and circadian rhythms disturbances as outcomes of seasonal affective disorder treatment: A systematic review

(2018) Giulia Menculini et al.   JOURNAL OF AFFECTIVE DISORDERS

Insights into the Role of Circadian Rhythms in Bone Metabolism: A Promising Intervention Target?

(2018) Chao Song et al.   Biomed Research International

Polychromatic Light Exposure as a Therapeutic in the Treatment and Management of Parkinson's Disease: A Controlled Exploratory Trial

(2018) Gregory L. Willis et al.   Frontiers in Neurology

Sleep problems in adults with autism spectrum disorder and intellectual disability

(2018) Pura Ballester et al.   Autism Research

Chronobiological dis-rhythmicity is related to emotion dysregulation and suicidality in depressive bipolar II disorder with mixed features

(2018) Laura Palagini et al.   PSYCHIATRY RESEARCH

Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers

(2017) Christopher J. Morris et al.   JOURNAL OF BIOLOGICAL RHYTHMS

The Association between Social Jetlag, the Metabolic Syndrome, and Type 2 Diabetes Mellitus in the General Population: The New Hoorn Study

(2017) Anitra D.M. Koopman et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans

(2017) Christine M Swanson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Seasonal variation in multiple sclerosis relapse

(2017) Katharine Harding et al.   JOURNAL OF NEUROLOGY

Sleep Deprivation and Caffeine Treatment Potentiate Photic Resetting of the Master Circadian Clock in a Diurnal Rodent

(2017) Pawan Kumar Jha et al.   JOURNAL OF NEUROSCIENCE

Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children With Autism Spectrum Disorder

(2017) Paul Gringras et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes

(2017) A Ehlers et al.   Mucosal Immunology

Two sides of a coin: ecological and chronobiological perspectives of timing in the wild

(2017) Barbara Helm et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Chronotype and circadian rhythm in bipolar disorder: A systematic review

(2017) Matias C.A. Melo et al.   SLEEP MEDICINE REVIEWS

The shift work and health research agenda: Considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease

(2017) Amy C. Reynolds et al.   SLEEP MEDICINE REVIEWS

Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease

(2017) Caroline E. Sutton et al.   Nature Communications

The CircadianClockMutation Promotes Intestinal Dysbiosis

(2016) Robin M. Voigt et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis

(2016) Nicole M. Kettner et al.   CANCER CELL

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

The circadian clock regulates inflammatory arthritis

(2016) Laura E. Hand et al.   FASEB JOURNAL

Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women

(2016) Céline Vetter et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Exercise in bipolar patients: A systematic review

(2016) Matias Carvalho Aguiar Melo et al.   JOURNAL OF AFFECTIVE DISORDERS

Effects of the Internal Circadian System and Circadian Misalignment on Glucose Tolerance in Chronic Shift Workers

(2016) Christopher J. Morris et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies

(2016) Ruth C. Travis et al.   JNCI-Journal of the National Cancer Institute

Comparative Review of Approved Melatonin Agonists for the Treatment of Circadian Rhythm Sleep-Wake Disorders

(2016) Wilbur P. Trey Williams et al.   PHARMACOTHERAPY

Moderate Changes in the Circadian System of Alzheimer's Disease Patients Detected in Their Home Environment

(2016) Kamila Weissová et al.   PLoS One

Circadian misalignment increases cardiovascular disease risk factors in humans

(2016) Christopher J. Morris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seasonal variations in mood and behavior associate with common chronic diseases and symptoms in a population-based study

(2016) Syaron Basnet et al.   PSYCHIATRY RESEARCH

Role of methotrexate chronotherapy in collagen-induced rheumatoid arthritis in rats

(2016) X. Wang et al.   ZEITSCHRIFT FUR RHEUMATOLOGIE

A New Perspective for Parkinson’s Disease: Circadian Rhythm

(2016) Siyue Li et al.   Neuroscience Bulletin

Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer’s disease-risk genes

(2016) Zhixiong Ma et al.   Scientific Reports

Insulin Restores an Altered Corneal Epithelium Circadian Rhythm in Mice with Streptozotocin-induced Type 1 Diabetes

(2016) Fang Song et al.   Scientific Reports

Efficacy of Bright Light Treatment, Fluoxetine, and the Combination in Patients With Nonseasonal Major Depressive Disorder

(2016) Raymond W. Lam et al.   JAMA Psychiatry

Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies

(2016) Ruth C. Travis et al.   JNCI-Journal of the National Cancer Institute

Shift work at young age is associated with increased risk of multiple sclerosis in a Danish population

(2016) S. Gustavsen et al.   Multiple Sclerosis and Related Disorders

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

(2016) Rohini V. Khapre et al.   Aging-US

Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans

(2015) Joshua L. Wang et al.   ANNALS OF NEUROLOGY

Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice

(2015) Linjie Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cost of circadian desynchrony: Evidence, insights and open questions

(2015) Alexander C. West et al.   BIOESSAYS

Synchronization of the mammalian circadian timing system: Light can control peripheral clocks independently of the SCN clock

(2015) Jana Husse et al.   BIOESSAYS

24-HOUR ACTIVITY RHYTHM AND SLEEP DISTURBANCES IN DEPRESSION AND ANXIETY: A POPULATION-BASED STUDY OF MIDDLE-AGED AND OLDER PERSONS

(2015) Annemarie I. Luik et al.   DEPRESSION AND ANXIETY

Mismatch of Sleep and Work Timing and Risk of Type 2 Diabetes

(2015) Céline Vetter et al.   DIABETES CARE

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

(2015) Michal Dudek et al.   JOURNAL OF CLINICAL INVESTIGATION

Circadian timing of metabolism in animal models and humans

(2015) C. Dibner et al.   JOURNAL OF INTERNAL MEDICINE

SLEEP AND CIRCADIAN RHYTHM REGULATION IN EARLY PARKINSON'S DISEASE

(2015) David Breen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Evaluation of the immunomodulatory effect of melatonin on the T-cell response in peripheral blood from systemic lupus erythematosus patients

(2015) Pablo Medrano-Campillo et al.   JOURNAL OF PINEAL RESEARCH

Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway

(2015) B. Guo et al.   OSTEOARTHRITIS AND CARTILAGE

Effects of caffeine on the human circadian clock in vivo and in vitro

(2015) Tina M. Burke et al.   Science Translational Medicine

Association of ARNTL and PER1 genes with Parkinson's disease: a case-control study of Han Chinese

(2015) Zhuqin Gu et al.   Scientific Reports

Altered salience network connectivity predicts macronutrient intake after sleep deprivation

(2015) Zhuo Fang et al.   Scientific Reports

Ageing and osteoarthritis: a circadian rhythm connection

(2014) Nicole Gossan et al.   BIOGERONTOLOGY

Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study

(2014) Zuleyha Akgun et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis

(2014) Christoph A. Thaiss et al.   CELL

Is Social Jetlag Associated with an Adverse Endocrine, Behavioral, and Cardiovascular Risk Profile?

(2014) Femke Rutters et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour

(2014) Subhashis Banerjee et al.   Nature Communications

Timing of circadian genes in mammalian tissues

(2014) Anja Korenčič et al.   Scientific Reports

Deficiency in PER proteins has no effect on the rate of spontaneous and radiation-induced carcinogenesis

(2013) Marina P Antoch et al.   CELL CYCLE

Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks

(2013) C. Saini et al.   GENES & DEVELOPMENT

Modulation by Melatonin of the Pathogenesis of Inflammatory Autoimmune Diseases

(2013) Gu-Jiun Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Shift Work or Food Intake during the Rest Phase Promotes Metabolic Disruption and Desynchrony of Liver Genes in Male Rats

(2013) Roberto C. Salgado-Delgado et al.   PLoS One

The role of the circadian clock in rheumatoid arthritis

(2013) Julie E Gibbs et al.   ARTHRITIS RESEARCH & THERAPY

The impact of sleep deprivation on food desire in the human brain

(2013) Stephanie M. Greer et al.   Nature Communications

Sex moderates circadian chemotherapy effects on survival of patients with metastatic colorectal cancer: a meta-analysis

(2012) S. Giacchetti et al.   ANNALS OF ONCOLOGY

Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice

(2012) M S Bray et al.   INTERNATIONAL JOURNAL OF OBESITY

Obesity in mice with adipocyte-specific deletion of clock component Arntl

(2012) Georgios K Paschos et al.   NATURE MEDICINE

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF

(2012) Stefanie Haas et al.   ARTHRITIS RESEARCH & THERAPY

Methotrexate Chronotherapy is Effective Against Rheumatoid Arthritis

(2011) Hideto To et al.   CHRONOBIOLOGY INTERNATIONAL

Circadian clock and cardiovascular disease

(2011) Norihiko Takeda et al.   Journal of Cardiology

Sleep and immune function

(2011) Luciana Besedovsky et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Is shift work a risk factor for rheumatoid arthritis? The Finnish Public Sector study

(2010) S. Puttonen et al.   ANNALS OF THE RHEUMATIC DISEASES

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

(2010) David K. Welsh et al.   Annual Review of Physiology

PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ

(2010) Benedetto Grimaldi et al.   Cell Metabolism

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

The role of retinal photoreceptors in the regulation of circadian rhythms

(2009) Ketema N. Paul et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

(2007) Molly S. Bray et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY