The circadian clock regulates inflammatory arthritis

Overexpression of circadian clock protein cryptochrome (CRY) 1 alleviates sleep deprivation-induced vascular inflammation in a mouse model

(2015) Bing Qin et al.   IMMUNOLOGY LETTERS

Overexpression of CRY1 protects against the development of atherosclerosis via the TLR/NF-κB pathway

(2015) Lei Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Impairment of Circadian Rhythms in Peripheral Clocks by Constant Light Is Partially Reversed by Scheduled Feeding or Exercise

(2015) Yutaro Hamaguchi et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian Clocks in the Immune System

(2015) Nathalie Labrecque et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice

(2015) Noriko Ando et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Effects of type of light on mouse circadian behaviour and stress levels

(2015) Marta Alves-Simoes et al.   LABORATORY ANIMALS

Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway

(2015) B. Guo et al.   OSTEOARTHRITIS AND CARTILAGE

Circadian control of innate immunity in macrophages by miR-155 targetingBmal1

(2015) Anne M. Curtis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myeloid Cell-specific Disruption ofPeriod1andPeriod2Exacerbates Diet-induced Inflammation and Insulin Resistance

(2014) Hang Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsic and extrinsic cues regulate the daily profile of mouse lateral habenula neuronal activity

(2014) Kanwal Sakhi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Clock gene Per1 regulates the production of CCL2 and interleukin-6 through p38, JNK1 and NF-κB activation in spinal astrocytes

(2014) Tatsuhiko Sugimoto et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action

(2014) Julie Gibbs et al.   NATURE MEDICINE

Circadian Disruption Leads to Insulin Resistance and Obesity

(2013) Shu-qun Shi et al.   CURRENT BIOLOGY

Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity

(2013) Claudia P. Coomans et al.   FASEB JOURNAL

The circadian clock is functional in eosinophils and mast cells

(2013) Anja Baumann et al.   IMMUNOLOGY

Circadian Timekeeping Is Disturbed in Rheumatoid Arthritis at Molecular Level

(2013) Vesa-Petteri Kouri et al.   PLoS One

Cardiac Per2 Functions as Novel Link between Fatty Acid Metabolism and Myocardial Inflammation during Ischemia and Reperfusion Injury of the Heart

(2013) Stephanie Bonney et al.   PLoS One

Circadian clock regulates the host response to Salmonella

(2013) M. M. Bellet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6Chi Inflammatory Monocytes

(2013) K. D. Nguyen et al.   SCIENCE

The role of the circadian clock in rheumatoid arthritis

(2013) Julie E Gibbs et al.   ARTHRITIS RESEARCH & THERAPY

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors

(2012) Nunzio Bottini et al.   Nature Reviews Rheumatology

Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines

(2012) R. Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Small Molecule Activators of Cryptochrome

(2012) T. Hirota et al.   SCIENCE

Gene expression profiling and functional analysis of angiogenic markers in murine collagen-induced arthritis

(2012) Yvonne Raatz et al.   ARTHRITIS RESEARCH & THERAPY

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF

(2012) Stefanie Haas et al.   ARTHRITIS RESEARCH & THERAPY

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

(2011) Laura A. Solt et al.   NATURE

Circadian Clocks in Mouse and Human CD4+ T Cells

(2011) Thomas Bollinger et al.   PLoS One

The nuclear receptor REV-ERB  mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

(2011) J. E. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSK4112, a Small Molecule Chemical Probe for the Cell Biology of the Nuclear Heme Receptor Rev-erbα

(2010) Daniel Grant et al.   ACS Chemical Biology

A circadian clock in murine bone marrow-derived mast cells modulates IgE-dependent activation in vitro

(2010) Xiaojia Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes*

(2010) Beatrice Haimovich et al.   CRITICAL CARE MEDICINE

Regulation of Adipogenesis by Natural and Synthetic REV-ERB Ligands

(2010) Naresh Kumar et al.   ENDOCRINOLOGY

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

(2010) O. Castanon-Cervantes et al.   JOURNAL OF IMMUNOLOGY

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Mammalian Clock Gene Cryptochrome Regulates Arthritis via Proinflammatory Cytokine TNF- 

(2009) A. Hashiramoto et al.   JOURNAL OF IMMUNOLOGY

A circadian clock in macrophages controls inflammatory immune responses

(2009) Maren Keller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overnight variations in cortisol, interleukin 6, tumour necrosis factor   and other cytokines in people with rheumatoid arthritis

(2008) M G Perry et al.   ANNALS OF THE RHEUMATIC DISEASES

Two Decades of Circadian Time

(2008) M. H. Hastings et al.   JOURNAL OF NEUROENDOCRINOLOGY