Ageing and osteoarthritis: a circadian rhythm connection

A Mechanosensory Pathway to the Drosophila Circadian Clock

(2014) A. Simoni et al.   SCIENCE

Involvement of the Circadian Rhythm and Inflammatory Cytokines in the Pathogenesis of Rheumatoid Arthritis

(2014) Kohsuke Yoshida et al.   Journal of Immunology Research

The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

(2013) Nicole Gossan et al.   ARTHRITIS AND RHEUMATISM

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Circadian Disruption Leads to Insulin Resistance and Obesity

(2013) Shu-qun Shi et al.   CURRENT BIOLOGY

Entrainment of the Human Circadian Clock to the Natural Light-Dark Cycle

(2013) Kenneth P. Wright et al.   CURRENT BIOLOGY

Different circadian expression of major matrix-related genes in various types of cartilage: modulation by light–dark conditions

(2013) Kiyomasa K. Honda et al.   JOURNAL OF BIOCHEMISTRY

Suprachiasmatic Astrocytes Modulate the Circadian Clock in Response to TNF- 

(2013) J. M. Duhart et al.   JOURNAL OF IMMUNOLOGY

Circadian Timekeeping Is Disturbed in Rheumatoid Arthritis at Molecular Level

(2013) Vesa-Petteri Kouri et al.   PLoS One

Prolonged Bioluminescence Monitoring in Mouse Ex Vivo Bone Culture Revealed Persistent Circadian Rhythms in Articular Cartilages and Growth Plates

(2013) Naoki Okubo et al.   PLoS One

Timing is important in medication administration: a timely review of chronotherapy research

(2013) Gagandeep Kaur et al.   International Journal of Clinical Pharmacy

Increased apoptotic chondrocytes in articular cartilage from adult heterozygous SirT1 mice

(2012) Odile Gabay et al.   ANNALS OF THE RHEUMATIC DISEASES

Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model

(2012) Odile Gabay et al.   ARTHRITIS AND RHEUMATISM

Effects of aging on articular cartilage homeostasis

(2012) Martin Lotz et al.   BONE

Differential Entrainment of Peripheral Clocks in the Rat by Glucocorticoid and Feeding

(2012) Mitsugu Sujino et al.   ENDOCRINOLOGY

Glucocorticoids as Entraining Signals for Peripheral Circadian Oscillators

(2012) Pınar Pezük et al.   ENDOCRINOLOGY

Clock Genes Influence Gene Expression in Growth Plate and Endochondral Ossification in Mice

(2012) Takeshi Takarada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aging Differentially Affects the Re-entrainment Response of Central and Peripheral Circadian Oscillators

(2012) M. T. Sellix et al.   JOURNAL OF NEUROSCIENCE

Evidence for Neuronal Desynchrony in the Aged Suprachiasmatic Nucleus Clock

(2012) S. Farajnia et al.   JOURNAL OF NEUROSCIENCE

The overexpression of SIRT1 inhibited osteoarthritic gene expression changes induced by interleukin-1β in human chondrocytes

(2012) Takehiko Matsushita et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

(2012) Darwin Jeyaraj et al.   NATURE

Obesity in mice with adipocyte-specific deletion of clock component Arntl

(2012) Georgios K Paschos et al.   NATURE MEDICINE

Metabolic syndrome meets osteoarthritis

(2012) Qi Zhuo et al.   Nature Reviews Rheumatology

Osteoarthritis year 2012 in review: biology

(2012) P.M. van der Kraan   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Identification of Small Molecule Activators of Cryptochrome

(2012) T. Hirota et al.   SCIENCE

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF

(2012) Stefanie Haas et al.   ARTHRITIS RESEARCH & THERAPY

Circadian clock protein BMAL1 regulates cellular senescence in vivo

(2011) Rohini V. Khapre et al.   CELL CYCLE

Evidence Suggesting that the Cardiomyocyte Circadian Clock Modulates Responsiveness of the Heart to Hypertrophic Stimuli in Mice

(2011) David J. Durgan et al.   CHRONOBIOLOGY INTERNATIONAL

Effects of pulsed electromagnetic fields on cartilage apoptosis signalling pathways in ovariectomised rats

(2011) Shasha Li et al.   INTERNATIONAL ORTHOPAEDICS

ADAMTS-4 and ADAMTS-5: Key enzymes in osteoarthritis

(2011) Priyanka Verma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Circadian Rhythm and Cartilage Extracellular Matrix Genes in Osseointegration: A Genome-Wide Screening of Implant Failure by Vitamin D Deficiency

(2011) Cristiane Machado Mengatto et al.   PLoS One

Serum factors in older individuals change cellular clock properties

(2011) L. Pagani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nuclear receptor REV-ERB  mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

(2011) J. E. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis

(2010) Beate Böhm et al.   ARTHRITIS AND RHEUMATISM

Why is osteoarthritis an age-related disease?

(2010) A. Shane Anderson et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag

(2010) Silke Kiessling et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function

(2010) J. L. Andrews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

(2010) E. D. Buhr et al.   SCIENCE

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

(2009) R.F. Loeser   OSTEOARTHRITIS AND CARTILAGE

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

Articular cartilage: structure, injuries and review of management

(2008) A. M. Bhosale et al.   BRITISH MEDICAL BULLETIN

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

(2008) Qing-Jun Meng et al.   NEURON

Physiological significance of a peripheral tissue circadian clock

(2008) K. A. Lamia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Gene Regulatory Networks in the Mammalian Circadian Rhythm

(2008) Jun Yan et al.   PLoS Computational Biology

Resetting of central and peripheral circadian oscillators in aged rats

(2006) Alec J. Davidson et al.   NEUROBIOLOGY OF AGING