Physiological functions and roles in cancer of the proliferation marker Ki-67

Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis

(2021) Karim Mrouj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chromatin-binding domain of Ki-67 together with p53 protects human chromosomes from mitotic damage

(2021) Osama Garwain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The intrinsically disorderly story of Ki-67

(2021) Lucy Remnant et al.   Open Biology

Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation

(2020) Fabian Erdel et al.   MOLECULAR CELL

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

(2020) Nadia Hégarat et al.   EMBO JOURNAL

MeCP2 links heterochromatin condensates and neurodevelopmental disease

(2020) Charles H. Li et al.   NATURE

Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly

(2020) Sara Cuylen-Haering et al.   NATURE

Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells

(2020) Hilmar Strickfaden et al.   CELL

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

(2019) Cornelia Kröger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

(2019) S. Sanulli et al.   NATURE

Ki-67 and condensins support the integrity of mitotic chromosomes through distinct mechanisms

(2018) Masatoshi Takagi et al.   JOURNAL OF CELL SCIENCE

Coactivator condensation at super-enhancers links phase separation and gene control

(2018) Benjamin R. Sabari et al.   SCIENCE

Identification of the tumour transition states occurring during EMT

(2018) Ievgenia Pastushenko et al.   NATURE

Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence

(2018) Iain Miller et al.   Cell Reports

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

(2018) Ann Boija et al.   CELL

Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells

(2017) Xiaoming Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

The p150N domain of chromatin assembly factor-1 regulates Ki-67 accumulation on the mitotic perichromosomal layer

(2017) Timothy D. Matheson et al.   MOLECULAR BIOLOGY OF THE CELL

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Ki-67 and the Chromosome Periphery Compartment in Mitosis

(2017) Daniel G. Booth et al.   TRENDS IN CELL BIOLOGY

Perichromosomal protein Ki67 supports mitotic chromosome architecture

(2016) Masatoshi Takagi et al.   GENES TO CELLS

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin

(2016) Daniel G. Booth et al.   MOLECULAR CELL

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

(2016) Sara Cuylen et al.   NATURE

Treating cancer with selective CDK4/6 inhibitors

(2016) Ben O'Leary et al.   Nature Reviews Clinical Oncology

On TADs and LADs: Spatial Control Over Gene Expression

(2016) Adriana Gonzalez-Sandoval et al.   TRENDS IN GENETICS

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation

(2016) Justin Cidado et al.   Oncotarget

A light-controlled switch after dual targeting of proliferating tumor cells via the membrane receptor EGFR and the nuclear protein Ki-67

(2016) Sijia Wang et al.   Scientific Reports

The cell proliferation antigen Ki-67 organises heterochromatin

(2016) Michal Sobecki et al.   eLife

The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

(2016) Ganesan Senthil Kumar et al.   eLife

Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67

(2015) Sijia Wang et al.   MOLECULAR PHARMACEUTICS

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

(2015) Xin Ye et al.   NATURE

The Mediator complex: a central integrator of transcription

(2015) Benjamin L. Allen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Ki67 Antigen Contributes to the Timely Accumulation of Protein Phosphatase 1γ on Anaphase Chromosomes

(2014) Masatoshi Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli

(2014) Corey L. Smith et al.   MOLECULAR BIOLOGY OF THE CELL

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery

(2014) Daniel G Booth et al.   eLife

Prognostic Value of a Combined Estrogen Receptor, Progesterone Receptor, Ki-67, and Human Epidermal Growth Factor Receptor 2 Immunohistochemical Score and Comparison With the Genomic Health Recurrence Score in Early Breast Cancer

(2011) Jack Cuzick et al.   JOURNAL OF CLINICAL ONCOLOGY

Ki-67 as a Molecular Target for Therapy in an In vitro Three-Dimensional Model for Ovarian Cancer

(2010) R. Rahmanzadeh et al.   CANCER RESEARCH

Excess histone levels mediate cytotoxicity via multiple mechanisms

(2010) Rakesh Kumar Singh et al.   CELL CYCLE

Protein dynamics and conformational disorder in molecular recognition

(2009) Tanja Mittag et al.   JOURNAL OF MOLECULAR RECOGNITION

Orchestrating nuclear envelope disassembly and reassembly during mitosis

(2009) Stephan Güttinger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of renal cancer cell growth in vitro and in vivo with oncolytic adenovirus armed short hairpin RNA targeting Ki-67 encoding mRNA

(2008) J-N Zheng et al.   CANCER GENE THERAPY

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates

(2008) J. D. Blethrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA