Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

CDK1-CCNB1 creates a spindle checkpoint–permissive state by enabling MPS1 kinetochore localization

(2019) Daniel Hayward et al.   JOURNAL OF CELL BIOLOGY

MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling

(2019) Tatiana Alfonso-Pérez et al.   JOURNAL OF CELL BIOLOGY

Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry

(2018) Suzanne Vigneron et al.   DEVELOPMENTAL CELL

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation

(2018) Bennie Lemmens et al.   MOLECULAR CELL

Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells

(2018) Scott Rata et al.   CURRENT BIOLOGY

Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis

(2017) Bernhard Strauss et al.   JOURNAL OF CELL BIOLOGY

PLK1 Activation in Late G2 Sets Up Commitment to Mitosis

(2017) Lilia Gheghiani et al.   Cell Reports

Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification

(2017) Thomas Zerjatke et al.   Cell Reports

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS

(2017) Tony Ly et al.   eLife

Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability

(2017) Ana Maria G Dumitru et al.   eLife

Two Bistable Switches Govern M Phase Entry

(2016) Satoru Mochida et al.   CURRENT BIOLOGY

A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

(2016) Michael J. Cundell et al.   JOURNAL OF CELL BIOLOGY

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

(2016) Sara Cuylen et al.   NATURE

Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors

(2016) Toyoaki Natsume et al.   Cell Reports

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

Tunable and reversible drug control of protein production via a self-excising degron

(2015) Hokyung K Chung et al.   Nature Chemical Biology

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1

(2015) Erik Voets et al.   Scientific Reports

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

Loss of Cdk2 and Cyclin A2 Impairs Cell Proliferation and Tumorigenesis

(2014) L. Gopinathan et al.   CANCER RESEARCH

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

(2014) Katharine L. Sackton et al.   NATURE

Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation

(2013) Lilian Kabeche et al.   NATURE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals

(2013) M. Alvarez-Fernandez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Quantitative Model for Ordered Cdk Substrate Dephosphorylation during Mitotic Exit

(2011) Céline Bouchoux et al.   CELL

Cyclin B1 is rate limiting but not essential for mitotic entry and progression in mammalian somatic cells

(2011) Deena V. Soni et al.   CELL CYCLE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative Proteomics Reveals the Basis for the Biochemical Specificity of the Cell-Cycle Machinery

(2011) Felicia Walton Pagliuca et al.   MOLECULAR CELL

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Cyclin A Promotes S-Phase Entry via Interaction with the Replication Licensing Factor Mcm7

(2010) T. Chibazakura et al.   MOLECULAR AND CELLULAR BIOLOGY

The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events

(2010) Delquin Gong et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative Reconstitution of Mitotic CDK1 Activation in Somatic Cell Extracts

(2010) Richard W. Deibler et al.   MOLECULAR CELL

Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation

(2010) Tatsuya Tsukahara et al.   NATURE

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

(2010) A. Gharbi-Ayachi et al.   SCIENCE

Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis

(2010) S. Mochida et al.   SCIENCE

Cyclin A Is Redundant in Fibroblasts but Essential in Hematopoietic and Embryonic Stem Cells

(2009) Ilona Kalaszczynska et al.   CELL

The M Phase Kinase Greatwall (Gwl) Promotes Inactivation of PP2A/B55δ, a Phosphatase Directed Against CDK Phosphosites

(2009) Priscila V. Castilho et al.   MOLECULAR BIOLOGY OF THE CELL

Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents

(2009) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Cyclin A-Cdk1 regulates the origin firing program in mammalian cells

(2009) Y. Katsuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis

(2008) Qiang Chen et al.   CELL RESEARCH

Kinase-Selective Enrichment Enables Quantitative Phosphoproteomics of the Kinome across the Cell Cycle

(2008) Henrik Daub et al.   MOLECULAR CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

(2008) Helfrid Hochegger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates

(2008) J. D. Blethrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA