The intrinsically disorderly story of Ki-67

Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis

(2021) Karim Mrouj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation

(2020) Fabian Erdel et al.   MOLECULAR CELL

Repetitive RNAs as Regulators of Chromatin-Associated Subcompartment Formation by Phase Separation

(2020) Lukas Frank et al.   JOURNAL OF MOLECULAR BIOLOGY

Nascent Transcript Folding Plays a Major Role in Determining RNA Polymerase Elongation Rates

(2020) Tomasz W. Turowski et al.   MOLECULAR CELL

Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder

(2020) Lovisa Stenström et al.   Molecular Systems Biology

Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly

(2020) Sara Cuylen-Haering et al.   NATURE

The nucleolus as a multiphase liquid condensate

(2020) Denis L. J. Lafontaine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heterochromatin as an Important Driver of Genome Organization

(2020) Andrés Penagos-Puig et al.   Frontiers in Cell and Developmental Biology

How do intrinsically disordered protein regions encode a driving force for liquid–liquid phase separation?

(2020) Wade Borcherds et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ribosomal DNA and the nucleolus in the context of genome organization

(2019) Tamara A. Potapova et al.   CHROMOSOME RESEARCH

Minichromosome Maintenance Proteins MCM-3, MCM-5, MCM-7, and Ki-67 as Proliferative Markers in Adrenocortical Tumors

(2019) MICHAL APOROWICZ et al.   ANTICANCER RESEARCH

Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein’s C-Terminal Helix

(2019) Benjamin R. Topacio et al.   MOLECULAR CELL

Ki‐67 and MCM6 labelling indices are correlated with overall survival in anaplastic oligodendroglioma, IDH1 ‐mutant and 1p/19q‐codeleted: a multicenter study from the French POLA network

(2019) Celso Pouget et al.   BRAIN PATHOLOGY

Getting out of mitosis: spatial and temporal control of mitotic exit and cytokinesis by PP 1 and PP 2A

(2019) James Holder et al.   FEBS LETTERS

Nucleolus: A Central Hub for Nuclear Functions

(2019) Olga V. Iarovaia et al.   TRENDS IN CELL BIOLOGY

The Nucleolus: A Multiphase Condensate Balancing Ribosome Synthesis and Translational Capacity in Health, Aging and Ribosomopathies

(2019) Carl C. Correll et al.   Cells

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

(2019) S. Sanulli et al.   NATURE

Ribosomal DNA and the Nucleolus as Keystones of Nuclear Architecture, Organization, and Function

(2019) Amanda V. Cerqueira et al.   TRENDS IN GENETICS

Protein phosphatases at the nuclear envelope

(2018) Raquel Sales Gil et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Ki-67 and condensins support the integrity of mitotic chromosomes through distinct mechanisms

(2018) Masatoshi Takagi et al.   JOURNAL OF CELL SCIENCE

Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis

(2018) Kumiko Samejima et al.   JOURNAL OF CELL SCIENCE

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

Cell Cycle Markers in the Evaluation of Bladder Cancer

(2018) Jéssica Niederauer Leote da Silva et al.   PATHOLOGY & ONCOLOGY RESEARCH

Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence

(2018) Iain Miller et al.   Cell Reports

Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells

(2018) Scott Rata et al.   CURRENT BIOLOGY

Mechanisms of nuclear pore complex assembly - two different ways of building one molecular machine

(2017) Shotaro Otsuka et al.   FEBS LETTERS

Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells

(2017) Xiaoming Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

The p150N domain of chromatin assembly factor-1 regulates Ki-67 accumulation on the mitotic perichromosomal layer

(2017) Timothy D. Matheson et al.   MOLECULAR BIOLOGY OF THE CELL

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

Ki-67 and the Chromosome Periphery Compartment in Mitosis

(2017) Daniel G. Booth et al.   TRENDS IN CELL BIOLOGY

Repo-Man/PP1 regulates heterochromatin formation in interphase

(2017) Inês J. de Castro et al.   Nature Communications

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Perichromosomal protein Ki67 supports mitotic chromosome architecture

(2016) Masatoshi Takagi et al.   GENES TO CELLS

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin

(2016) Daniel G. Booth et al.   MOLECULAR CELL

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

(2016) Sara Cuylen et al.   NATURE

A comparison of phosphospecific affinity reagents reveals the utility of recombinant Forkhead-associated domains in recognizing phosphothreonine-containing peptides

(2016) Leon A. Venegas et al.   New Biotechnology

Prognostic value of Ki67 in localized prostate carcinoma: a multi-institutional study of >1000 prostatectomies

(2016) M S Tretiakova et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Ki-67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas

(2016) Eleonora Duregon et al.   Oncotarget

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation

(2016) Justin Cidado et al.   Oncotarget

The cell proliferation antigen Ki-67 organises heterochromatin

(2016) Michal Sobecki et al.   eLife

The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

(2016) Ganesan Senthil Kumar et al.   eLife

Ki-67 as a prognostic marker according to breast cancer molecular subtype

(2016) A. Soliman Nahed et al.   Cancer Biology & Medicine

Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore

(2015) Itaru Samejima et al.   JOURNAL OF CELL BIOLOGY

Expression of proliferation markers Ki67, cyclin A, geminin and aurora-kinase A in primary breast carcinomas and corresponding distant metastases

(2015) Anna-Mária Tökés et al.   JOURNAL OF CLINICAL PATHOLOGY

Co-Expression of p16, Ki67 and COX-2 Is Associated with Basal Phenotype in High-Grade Ductal Carcinoma In Situ of the Breast

(2015) Amanda Arantes Perez et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Ki-67 labeling index affects tumor infiltration patterns of lung squamous cell carcinoma

(2015) DAISUKE MASUDA et al.   Molecular Medicine Reports

DNA content of a functioning chicken kinetochore

(2014) Susana Abreu Ribeiro et al.   CHROMOSOME RESEARCH

Aurora kinase A is superior to Ki67 as a prognostic indicator of survival in neuroblastoma

(2014) Pramila Ramani et al.   HISTOPATHOLOGY

Ki67 Antigen Contributes to the Timely Accumulation of Protein Phosphatase 1γ on Anaphase Chromosomes

(2014) Masatoshi Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli

(2014) Corey L. Smith et al.   MOLECULAR BIOLOGY OF THE CELL

A PP1–PP2A phosphatase relay controls mitotic progression

(2014) Agnes Grallert et al.   NATURE

Grading of Neuroendocrine Neoplasms: Mitoses and Ki-67 Are Both Essential

(2014) Marie-Louise F. van Velthuysen et al.   NEUROENDOCRINOLOGY

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery

(2014) Daniel G Booth et al.   eLife

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila

(2013) S. C. R. Elgin et al.   Cold Spring Harbor Perspectives in Biology

Expression of minichromosome maintenance 2, Ki-67, and geminin in oral nevi and melanoma

(2012) Bruno Augusto Benevenuto de Andrade et al.   Annals of Diagnostic Pathology

Repo-Man-PP1

(2012) Paola Vagnarelli et al.   Nucleus

Evolution and disorder

(2011) Celeste J Brown et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit

(2011) Paola Vagnarelli et al.   DEVELOPMENTAL CELL

Analysis of human Ki-67 gene promoter and identification of the Sp1 binding sites for Ki-67 transcription

(2011) Dong-Sheng Pei et al.   TUMOR BIOLOGY

Heterochromatin maintenance and establishment: Lessons from the mouse pericentromere

(2011) Geneviève Almouzni et al.   Nucleus

Assembly and disassembly of the nucleolus during the cell cycle

(2011) Danièle Hernandez-Verdun   Nucleus

The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics

(2010) Shinya Ohta et al.   CELL

The Nucleolus

(2010) T. Pederson   Cold Spring Harbor Perspectives in Biology

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

A ‘higher order’ of telomere regulation: telomere heterochromatin and telomeric RNAs

(2009) Stefan Schoeftner et al.   EMBO JOURNAL

Condensin Regulates the Stiffness of Vertebrate Centromeres

(2009) Susana A. Ribeiro et al.   MOLECULAR BIOLOGY OF THE CELL

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates

(2008) J. D. Blethrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA