Metabolic Modification in Gastrointestinal Cancer Stem Cells: Characteristics and Therapeutic Approaches
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Title
Metabolic Modification in Gastrointestinal Cancer Stem Cells: Characteristics and Therapeutic Approaches
Authors
Keywords
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Journal
JOURNAL OF CELLULAR PHYSIOLOGY
Volume 231, Issue 10, Pages 2081-2087
Publisher
Wiley
Online
2016-01-21
DOI
10.1002/jcp.25318
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Note: Only part of the references are listed.- Inhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells
- (2016) Bal Krishan Sharma et al. FASEB JOURNAL
- Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells
- (2016) Giovanna Talarico et al. Scientific Reports
- Innovation in metabolomics to improve personalized healthcare
- (2015) Stefano Cacciatore et al. Annals of the New York Academy of Sciences
- Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis
- (2015) H. I. Wettersten et al. CANCER RESEARCH
- SIRT1/PGC1 -Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer
- (2015) T. T. Vellinga et al. CLINICAL CANCER RESEARCH
- Sensitization of Chemo-Resistant Human Chronic Myeloid Leukemia Stem-Like Cells to Hsp90 Inhibitor by SIRT1 Inhibition
- (2015) Hak-Bong Kim et al. International Journal of Biological Sciences
- Nitric Oxide Up-Regulates RUNX2 in LNCaP Prostate Tumours: Implications for Tumour Growth In Vitro and In Vivo
- (2015) Heather Nesbitt et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Carbonic Anhydrase 9 mRNA/microRNA34a Interplay in Hypoxic Human Mammospheres
- (2015) Sabrina De Carolis et al. JOURNAL OF CELLULAR PHYSIOLOGY
- LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1α and Stat3 Signaling
- (2015) Fei Niu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Concise Review: The Role of Oxygen in Hematopoietic Stem Cell Physiology
- (2015) Mojca Jež et al. JOURNAL OF CELLULAR PHYSIOLOGY
- High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells
- (2015) Maria Ausiliatrice Puglisi et al. JOURNAL OF PATHOLOGY
- Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target
- (2015) Ryoichi Asaka et al. LABORATORY INVESTIGATION
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- Glutaminolysis as a target for cancer therapy
- (2015) L Jin et al. ONCOGENE
- Redox Regulation in Cancer Stem Cells
- (2015) Shijie Ding et al. Oxidative Medicine and Cellular Longevity
- Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions
- (2015) Alessandra Silvestri et al. PLoS One
- Emerging role of silent information regulator 1 (SIRT1) in hepatocellular carcinoma: a potential therapeutic target
- (2015) Yuting Wu et al. TUMOR BIOLOGY
- Metformin inhibits the proliferation, metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cells in vitro
- (2015) Xu Chen et al. TUMOR BIOLOGY
- MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer
- (2015) Peter C. Hart et al. Nature Communications
- Dysregulation of the miR-34a-SIRT1 axis inhibits breast cancer stemness
- (2015) Wei Ma et al. Oncotarget
- Metabolomic profile in pancreatic cancer patients: a consensus-based approach to identify highly discriminating metabolites
- (2015) Iole Maria Di Gangi et al. Oncotarget
- Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration
- (2015) Jiaojiao He et al. Scientific Reports
- Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies
- (2015) Enza Lonardo et al. Jove-Journal of Visualized Experiments
- ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways
- (2015) Surendra Singh et al. PLoS One
- ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-κB-dependent activation of Snail
- (2015) Magdalena A. Cichon et al. Oncotarget
- CPEB1 modulates differentiation of glioma stem cells via downregulation of HES1 and SIRT1 expression
- (2015) Jinlong Yin et al. Oncotarget
- Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
- (2015) Marta Gritti et al. Oncotarget
- Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression
- (2014) Shu-Ching Hsieh et al. AMINO ACIDS
- Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy
- (2014) Alba Luengo et al. BMC BIOLOGY
- SIRT1 Activation by a c-MYC Oncogenic Network Promotes the Maintenance and Drug Resistance of Human FLT3-ITD Acute Myeloid Leukemia Stem Cells
- (2014) Ling Li et al. Cell Stem Cell
- Metformin: A Potential Therapeutic Agent for Recurrent Colon Cancer
- (2014) Pratima Nangia-Makker et al. PLoS One
- Disulfiram Eradicates Tumor-Initiating Hepatocellular Carcinoma Cells in ROS-p38 MAPK Pathway-Dependent and -Independent Manners
- (2014) Tetsuhiro Chiba et al. PLoS One
- Hypoxia-Inducible Factors Modulate the Stemness and Malignancy of Colon Cancer Cells by Playing Opposite Roles in Canonical Wnt Signaling
- (2014) Paula Santoyo-Ramos et al. PLoS One
- Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
- (2014) A. Janzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor Initiating Cells and Chemoresistance: Which Is the Best Strategy to Target Colon Cancer Stem Cells?
- (2014) Emanuela Paldino et al. Biomed Research International
- Metabostemness: A New Cancer Hallmark
- (2014) Javier A. Menendez et al. Frontiers in Oncology
- Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells
- (2013) Haitao Zhu et al. Cancer Cell International
- The Warburg effect version 2.0: Metabolic reprogramming of cancer stem cells
- (2013) JAVIER MENENDEZ et al. CELL CYCLE
- Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway
- (2013) P-P Liu et al. CELL DEATH AND DIFFERENTIATION
- Aerobic glycolysis: a novel target in kidney cancer
- (2013) Brian Shuch et al. Expert Review of Anticancer Therapy
- Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels
- (2013) Scott K. Parks et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Sirtuins' modulation of autophagy
- (2013) Fanny Ng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Differential effect of hypoxia on etoposide-induced DNA damage response and p53 regulation in different cell types
- (2013) Audrey Sermeus et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2013) Min Shen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
- (2013) Russell A. Miller et al. NATURE
- SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
- (2013) B Mao et al. ONCOGENE
- Low Concentrations of Metformin Selectively Inhibit CD133+ Cell Proliferation in Pancreatic Cancer and Have Anticancer Action
- (2013) Shanmiao Gou et al. PLoS One
- Metformin, a Diabetes Drug, Eliminates Tumor-Initiating Hepatocellular Carcinoma Cells
- (2013) Tomoko Saito et al. PLoS One
- The Enhanced Metastatic Potential of Hepatocellular Carcinoma (HCC) Cells with Sorafenib Resistance
- (2013) Ariel Ka-Man Chow et al. PLoS One
- Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
- (2013) H. A. Hirsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-Cell Metabolomics: Analytical and Biological Perspectives
- (2013) R. Zenobi SCIENCE
- Colon cancer stem cells: Controversies and perspectives
- (2013) Maria Ausiliatrice Puglisi WORLD JOURNAL OF GASTROENTEROLOGY
- Reactive Oxygen Species in Cancer Stem Cells
- (2012) Xiaoke Shi et al. ANTIOXIDANTS & REDOX SIGNALING
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth
- (2012) Claudia Capparelli et al. CELL CYCLE
- Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells
- (2012) Yoshihide Shimojo et al. CLINICAL & EXPERIMENTAL METASTASIS
- Hypoxia Induces EMT in Low and Highly Aggressive Pancreatic Tumor Cells but Only Cells with Cancer Stem Cell Characteristics Acquire Pronounced Migratory Potential
- (2012) Alexei V. Salnikov et al. PLoS One
- Effective Elimination of Cancer Stem Cells By a Novel Drug Combination Strategy
- (2012) Shuqiang Yuan et al. STEM CELLS
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- EMT and Oxidative Stress: A Bidirectional Interplay Affecting Tumor Malignancy
- (2011) Elisa Giannoni et al. ANTIOXIDANTS & REDOX SIGNALING
- From cancer metabolism to new biomarkers and drug targets
- (2011) F. Chiaradonna et al. BIOTECHNOLOGY ADVANCES
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2
- (2011) Christine E. Eyler et al. CELL
- Gemcitabine response in pancreatic adenocarcinoma cells is synergistically enhanced by dithiocarbamate derivatives
- (2011) Elisa Dalla Pozza et al. FREE RADICAL BIOLOGY AND MEDICINE
- Intestinal Inflammation and Cancer
- (2011) Thomas A. Ullman et al. GASTROENTEROLOGY
- Stromal–epithelial metabolic coupling in cancer: Integrating autophagy and metabolism in the tumor microenvironment
- (2011) Ubaldo E. Martinez-Outschoorn et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Targeting mitochondria as a therapeutic target in cancer
- (2011) Charles E. Wenner JOURNAL OF CELLULAR PHYSIOLOGY
- Regulation of reactive oxygen species in stem cells and cancer stem cells
- (2011) Chiharu I. Kobayashi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inflammation meets cancer, with NF-κB as the matchmaker
- (2011) Yinon Ben-Neriah et al. NATURE IMMUNOLOGY
- Prisoner's Dilemma in Cancer Metabolism
- (2011) Irina Kareva PLoS One
- Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells
- (2010) Yukihiro Akao et al. CANCER LETTERS
- Upregulation of mitochondrial function and antioxidant defense in the differentiation of stem cells
- (2009) Chien-Tsun Chen et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis
- (2009) E. H. Huang et al. CANCER RESEARCH
- Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
- (2009) H. A. Hirsch et al. CANCER RESEARCH
- Physiologic Oxygen Concentration Enhances the Stem-Like Properties of CD133+ Human Glioblastoma Cells In vitro
- (2009) A. M. McCord et al. MOLECULAR CANCER RESEARCH
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells
- (2008) Chien-Tsun Chen et al. STEM CELLS
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