Nitric Oxide Up-Regulates RUNX2 in LNCaP Prostate Tumours: Implications for Tumour Growth In Vitro and In Vivo

Runx2-smad signaling impacts the progression of tumor-induced bone disease

(2014) Xuhui Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Pro-survival and pro-growth effects of stress-induced nitric oxide in a prostate cancer photodynamic therapy model

(2013) Reshma Bhowmick et al.   CANCER LETTERS

The yin and yang of nitric oxide in cancer progression

(2013) A. J. Burke et al.   CARCINOGENESIS

Parathyroid hormone–related protein protects renal tubuloepithelial cells from apoptosis by activating transcription factor Runx2

(2013) Juan A Ardura et al.   KIDNEY INTERNATIONAL

Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistance

(2012) G Browne et al.   BRITISH JOURNAL OF CANCER

Increased expression of activated endothelial nitric oxide synthase contributes to antiandrogen resistance in prostate cancer cells by suppressing androgen receptor transactivation

(2012) Shan Yu et al.   CANCER LETTERS

Cytoprotective Signaling Associated with Nitric Oxide Upregulation in Tumor Cells Subjected to Photodynamic Therapy-like Oxidative Stress

(2012) Reshma Bhowmick et al.   FREE RADICAL BIOLOGY AND MEDICINE

Androgen deprivation results in time-dependent hypoxia in LNCaP prostate tumours: Informed scheduling of the bioreductive drug AQ4N improves treatment response

(2012) Louise Ming et al.   INTERNATIONAL JOURNAL OF CANCER

Runx2 Protein Stabilizes Hypoxia-inducible Factor-1α through Competition with von Hippel-Lindau Protein (pVHL) and Stimulates Angiogenesis in Growth Plate Hypertrophic Chondrocytes

(2012) Sun-Hee Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Latest UK figures show increase in prostate cancer diagnoses and falling death rate

(2012) S. Mayor   BMJ-British Medical Journal

Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development

(2011) Ming Ding et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

Guidelines for the welfare and use of animals in cancer research

(2010) P Workman et al.   BRITISH JOURNAL OF CANCER

Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression

(2009) J. Pratap et al.   CANCER RESEARCH

Runx2-mediatedbcl-2gene expression contributes to nitric oxide protection against hydrogen peroxide-induced osteoblast apoptosis

(2009) Wei-Pin Ho et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Endothelial NOS, estrogen receptor β, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer

(2009) Simona Nanni et al.   JOURNAL OF CLINICAL INVESTIGATION

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

(2009) J Akech et al.   ONCOGENE

Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients

(2008) C. Braconi et al.   ANNALS OF ONCOLOGY

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

(2008) J. Pratap et al.   CANCER RESEARCH

Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype

(2008) Karl T. Butterworth et al.   INTERNATIONAL JOURNAL OF CANCER

Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin

(2008) Verena Fetz et al.   INTERNATIONAL JOURNAL OF CANCER

Nitric oxide-p38 MAPK signaling stabilizes mRNA through AU-rich element-dependent and -independent mechanisms

(2008) S. Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY