Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression
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Title
Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression
Authors
Keywords
Hepatocellular carcinoma cells, Metformin, Invasion, Migration, MMP-9, uPA, Sorafenib
Journal
AMINO ACIDS
Volume 46, Issue 12, Pages 2809-2822
Publisher
Springer Nature
Online
2014-09-22
DOI
10.1007/s00726-014-1838-4
References
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