Metabolic Profiling, Chemical Composition, Antioxidant Capacity, and In Vivo Hepato- and Nephroprotective Effects of Sonchus cornutus in Mice Exposed to Cisplatin

Determination of Daphnetin and its 8-O-Methylated Metabolite in Rat Plasma by UFLC-MS/MS: Application to a Pharmacokinetic Study

(2022) Zhongqiong Wang et al.   CHROMATOGRAPHIA

Mitigation of IL-1β, IL-6, TNF-α, and markers of apoptosis by ursolic acid against cisplatin-induced oxidative stress and nephrotoxicity in rats

(2022) Pankaj Tripathi et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Anticancer Effects of New Ceramides Isolated from the Red Sea Red Algae Hypnea musciformis in a Model of Ehrlich Ascites Carcinoma: LC-HRMS Analysis Profile and Molecular Modeling

(2022) Sameh S. Elhady et al.   Marine Drugs

Caffeic acid protects against DNA damage, oxidative and inflammatory mediated toxicities, and upregulated caspases activation in the hepatorenal system of rats treated with aflatoxin B1

(2022) Solomon E. Owumi et al.   TOXICON

Hesperidin ameliorates cisplatin induced hepatotoxicity and attenuates oxidative damage, cell apoptosis, and inflammation in rats

(2022) Dina M. Aboraya et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Dissecting the Crosstalk Between Nrf2 and NF-κB Response Pathways in Drug-Induced Toxicity

(2022) Wen Gao et al.   Frontiers in Cell and Developmental Biology

Natural products: potential treatments for cisplatin-induced nephrotoxicity

(2021) Chun-yan Fang et al.   ACTA PHARMACOLOGICA SINICA

The Plants of the Asteraceae Family as Agents in the Protection of Human Health

(2021) Agata Rolnik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations

(2021) Kristen Renee McSweeney et al.   Cancers

Antibacterial Potential by Rupture Membrane and Antioxidant Capacity of Purified Phenolic Fractions of Persea americana Leaf Extract

(2021) Laura María Solís-Salas et al.   Antibiotics-Basel

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

(2021) Henry Jay Forman et al.   NATURE REVIEWS DRUG DISCOVERY

The role of natural antioxidants in cisplatin-induced hepatotoxicity

(2021) Norhashima Abd Rashid et al.   BIOMEDICINE & PHARMACOTHERAPY

Fraxetin induces cell death in colon cancer cells via mitochondria dysfunction and enhances therapeutic effects in 5‐fluorouracil resistant cells

(2021) Minkyeong Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

In Vitro and In Vivo Studies of Anti-Lung Cancer Activity of Artemesia judaica L. Crude Extract Combined with LC-MS/MS Metabolic Profiling, Docking Simulation and HPLC-DAD Quantification

(2021) Marwa S. Goda et al.   Antioxidants

Plicosepalus acacia Extract and Its Major Constituents, Methyl Gallate and Quercetin, Potentiate Therapeutic Angiogenesis in Diabetic Hind Limb Ischemia: HPTLC Quantification and LC-MS/MS Metabolic Profiling

(2021) Asmaa R. Abdel-Hamed et al.   Antioxidants

Chemical Composition of the Red Sea Green Algae Ulva lactuca: Isolation and In Silico Studies of New Anti-COVID-19 Ceramides

(2021) Enas E. Eltamany et al.   Metabolites

Evaluation of Renoprotective Effects of Our Locally Grown Green Coffee Beans against Cisplatin-Induced Nephrotoxicity in Swiss Albino Mice

(2021) Bati Leta et al.   International Journal of Nephrology

Thalassosterol, a New Cytotoxic Aromatase Inhibitor Ergosterol Derivative from the Red Sea Seagrass Thalassodendron ciliatum

(2020) Reda F. A. Abdelhameed et al.   Marine Drugs

Formononetin protects against cisplatin‑induced acute kidney injury through activation of the PPARα/Nrf2/HO‑1/NQO1 pathway

(2020) Yan Hao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation

(2020) Sarmistha Saha et al.   MOLECULES

Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress

(2020) Hao Wang et al.   Frontiers in Pharmacology

Chemical Profiling, Antioxidant, Cytotoxic Activities and Molecular Docking Simulation of Carrichtera annua DC. (Cruciferae)

(2020) Enas E. Eltamany et al.   Antioxidants

Daphnetin: A Novel Anti-Helicobacter pylori Agent

(2019) Genzhu Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cisplatin: The first metal based anticancer drug

(2019) Sumit Ghosh   BIOORGANIC CHEMISTRY

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

(2019) Kaio Murilo Monteiro Espíndola et al.   Frontiers in Oncology

The Effects and Mechanisms of Cyanidin-3-Glucoside and Its Phenolic Metabolites in Maintaining Intestinal Integrity

(2019) Jijun Tan et al.   Antioxidants

Chlorogenic acid (CGA): A pharmacological review and call for further research

(2018) Muhammad Naveed et al.   BIOMEDICINE & PHARMACOTHERAPY

Cytochrome P450S and Alcoholic Liver Disease

(2018) Yongke Lu et al.   CURRENT PHARMACEUTICAL DESIGN

Chlorogenic acid prevents diabetic nephropathy by inhibiting oxidative stress and inflammation through modulation of the Nrf2/HO-1 and NF-ĸB pathways

(2018) Liping Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Research progress of Sonchus species

(2018) Xiu-Mei Li et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

Nephroprotective Effect of Sonchus oleraceus Extract against Kidney Injury Induced by Ischemia-Reperfusion in Wistar Rats

(2018) Liliana Torres-González et al.   Oxidative Medicine and Cellular Longevity

Mangiferin Ameliorates Cisplatin Induced Acute Kidney Injury by Upregulating Nrf-2 via the Activation of PI3K and Exhibits Synergistic Anticancer Activity With Cisplatin

(2018) Pritam Sadhukhan et al.   Frontiers in Pharmacology

Simultaneous Determination of Aesculin, Aesculetin, Fraxetin, Fraxin and Polydatin in Beagle Dog Plasma by UPLC-ESI-MS/MS and Its Application in a Pharmacokinetic Study after Oral Administration Extracts of Ledum palustre L.

(2018) Zhibin Wang et al.   MOLECULES

Protective effect of dexpanthenol against cisplatin‑induced hepatotoxicity

(2018) Yilmaz Bilgic et al.   Experimental and Therapeutic Medicine

Daphnetin protects against cisplatin-induced nephrotoxicity by inhibiting inflammatory and oxidative response

(2018) Lina Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Proanthocyanidin protects against cisplatin-induced oxidative liver damage through inhibition of inflammation and NF-κβ/TLR-4 pathway

(2017) Nagla A El-Shitany et al.   ENVIRONMENTAL TOXICOLOGY

Anthocyanins Profile by Q-TOF LC/MS in Myrtus communis Berries from Salento Area

(2017) Sonia Scorrano et al.   Food Analytical Methods

Up-regulation of Nrf2-antioxidant signaling by Açaí ( Euterpe oleracea Mart.) extract prevents oxidative stress in human endothelial cells

(2017) Elaine R. Soares et al.   Journal of Functional Foods

Nebivolol Ameliorates Cisplatin-Induced Nephrotoxicity in Rats

(2016) Mohamed A. Morsy et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Delphinidin-3-glucoside suppresses breast carcinogenesis by inactivating the Akt/HOTAIR signaling pathway

(2016) Xiaohong Yang et al.   BMC CANCER

Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?

(2016) Tarique Hussain et al.   Oxidative Medicine and Cellular Longevity

Organ- and species-specific biological activity of rosmarinic acid

(2016) R. Iswandana et al.   TOXICOLOGY IN VITRO

Infliximab Modulates Cisplatin-Induced Hepatotoxicity in Rats

(2016) Medine Cumhur Cure et al.   Balkan Medical Journal

Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis

(2016) Hany A. Omar et al.   PLoS One

HPLC–DAD–ESI-MS/MS screening of bioactive components from Rhus coriaria L. (Sumac) fruits

(2015) Ibrahim M. Abu-Reidah et al.   FOOD CHEMISTRY

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

(2015) Ergul Belge Kurutas   Nutrition Journal

Allelopathic effects of Sonchus oleraceus L. on the germination and seedling growth of crop and weed species

(2014) Nasr Hassan Gomaa et al.   Acta Botanica Brasilica

Nephroprotective activities of rosmarinic acid against cisplatin-induced kidney injury in mice

(2014) Robert Domitrović et al.   FOOD AND CHEMICAL TOXICOLOGY

Anti-inflammatory and Protective Properties of Daphnetin in Endotoxin-Induced Lung Injury

(2014) Wen-wen Yu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antibacterial mechanism of fraxetin against Staphylococcus aureus

(2014) HAITING WANG et al.   Molecular Medicine Reports

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

Immunosuppressive Activity of Daphnetin, One of Coumarin Derivatives, Is Mediated through Suppression of NF-κB and NFAT Signaling Pathways in Mouse T Cells

(2014) Bocui Song et al.   PLoS One

Ameliorative Effect of Fisetin on Cisplatin-Induced Nephrotoxicity in Rats via Modulation of NF-κB Activation and Antioxidant Defence

(2014) Bidya Dhar Sahu et al.   PLoS One

Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury

(2014) Robert Domitrović et al.   TOXICOLOGY

Azadirachta indicaAttenuates Cisplatin-Induced Nephrotoxicity and Oxidative Stress

(2014) Ahmed E. Abdel Moneim et al.   Biomed Research International

Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions

(2013) Rossella Marullo et al.   PLoS One

Luteolin ameliorates cisplatin-induced nephrotoxicity in mice through inhibition of platinum accumulation, inflammation and apoptosis in the kidney

(2013) Robert Domitrović et al.   TOXICOLOGY

Bauhinia variegataLeaf Extracts Exhibit Considerable Antibacterial, Antioxidant, and Anticancer Activities

(2013) Amita Mishra et al.   Biomed Research International

Protective effects of Sonchus asper (L.) Hill, (Asteraceae) against CCl4-induced oxidative stress in the thyroid tissue of rats

(2012) Rahmat Ali Khan   BMC Complementary and Alternative Medicine

Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial

(2012) Rahmat A Khan et al.   BMC Complementary and Alternative Medicine

Evaluation of flavonoids and diverse antioxidant activities of Sonchus arvensis

(2012) Rahmat Ali Khan   Chemistry Central Journal

Evaluation of phenolic contents and antioxidant activity of various solvent extracts of Sonchus asper (L.) Hill

(2012) Rahmat Ali Khan et al.   Chemistry Central Journal

Cyanidin-3-rutinoside alleviates postprandial hyperglycemia and its synergism with acarbose by inhibition of intestinal α-glucosidase

(2011) Sirichai Adisakwattana et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Biochemical Study of Oxidative Stress Markers in the Liver, Kidney and Heart of High Fat Diet Induced Obesity in Rats

(2011) Saad A Noeman et al.   Diabetology & Metabolic Syndrome

Prevention of CCl4-induced nephrotoxicity with Sonchus asper in rat

(2010) Rahmat Ali Khan et al.   FOOD AND CHEMICAL TOXICOLOGY

An LC–MS/MS method for the simultaneous determination of chlorogenic acid, forsythiaside A and baicalin in rat plasma and its application to pharmacokinetic study of Shuang-huang-lian in rats

(2010) Jun-Xiao Ye et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

A rapid and sensitive LC–MS/MS method for quantification of four anthocyanins and its application in a clinical pharmacology study of a bioadhesive black raspberry gel

(2009) Yonghua Ling et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Efficacy of caffeic acid in preventing nickel induced oxidative damage in liver of rats

(2008) L. Pari et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols