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Title
Galectin-9: From cell biology to complex disease dynamics
Authors
Keywords
Cancer, carbohydrate recognition domain, galectin-9, immune-regulation, linker peptide
Journal
JOURNAL OF BIOSCIENCES
Volume 41, Issue 3, Pages 507-534
Publisher
Springer Nature
Online
2016-07-16
DOI
10.1007/s12038-016-9616-y
References
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- (2015) Hirofumi Hirao et al. LIVER TRANSPLANTATION
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- (2015) Y.-f. Tao et al. TRANSPLANTATION PROCEEDINGS
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- (2014) Xinwei Qiao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2014) Youko Fukata et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2014) Yingying Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2014) Anita Johswich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) K. Nagahara et al. JOURNAL OF IMMUNOLOGY
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- (2013) Andrew J. Steelman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2013) Z.-H. Tang et al. JOURNAL OF IMMUNOLOGY
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- (2013) K. L. Clayton et al. JOURNAL OF IMMUNOLOGY
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- (2013) Marloes J. M. Gooden et al. PLoS One
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- (2011) P. B. J. Reddy et al. JOURNAL OF IMMUNOLOGY
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- (2011) M. Stancic et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
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- (2011) S. Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) S. Bi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) Hideru Obinata et al. Seminars in Immunopathology
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- (2010) Dolores Solís et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- (2010) Hiromi Yoshida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) T Kobayashi et al. LEUKEMIA
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- (2009) Tomohiro Arikawa et al. BONE
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- (2009) Lawrence Rajendran et al. NATURE REVIEWS DRUG DISCOVERY
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- (2009) N. G. Than et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Victor L. Thijssen et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2008) Jochen Wedemeyer et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
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- (2008) M. Nagae et al. GLYCOBIOLOGY
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- (2008) A. Nobumoto et al. GLYCOBIOLOGY
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- (2008) Meiyan Liang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
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- (2007) Masamichi Nagae et al. JOURNAL OF MOLECULAR BIOLOGY
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