标题
Galectin-9: From cell biology to complex disease dynamics
作者
关键词
Cancer, carbohydrate recognition domain, galectin-9, immune-regulation, linker peptide
出版物
JOURNAL OF BIOSCIENCES
Volume 41, Issue 3, Pages 507-534
出版商
Springer Nature
发表日期
2016-07-16
DOI
10.1007/s12038-016-9616-y
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cerebrospinal fluid concentration of Galectin-9 is increased in secondary progressive multiple sclerosis
- (2016) Joachim Burman et al. JOURNAL OF NEUROIMMUNOLOGY
- Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway
- (2016) Jintang Sun et al. PLoS One
- A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression
- (2015) Yoshikane Kikushige et al. Cell Stem Cell
- The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal–fetal interface in early pregnancy
- (2015) Yan-Hong Li et al. Cellular & Molecular Immunology
- Upregulation of the Tim-3/Gal-9 pathway and correlation with the development of preeclampsia
- (2015) Haiyan Hao et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- The protective function of galectin-9 in liver ischemia and reperfusion injury in mice
- (2015) Hirofumi Hirao et al. LIVER TRANSPLANTATION
- Galectin-9 in Combination With EX-527 Prolongs the Survival of Cardiac Allografts in Mice After Cardiac Transplantation
- (2015) Y.-f. Tao et al. TRANSPLANTATION PROCEEDINGS
- Increased expression of Tim-3 and its ligand Galectin-9 in rat allografts during acute rejection episodes
- (2014) Xinwei Qiao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Direct cytocidal effect of galectin-9 localized on collagen matrices on human immune cell lines
- (2014) Youko Fukata et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells
- (2014) Chuan Wu et al. IMMUNITY
- Galectin-9 Induced Myeloid Suppressor Cells Expand Regulatory T Cells in an IL-10-Dependent Manner in CVB3-Induced Acute Myocarditis
- (2014) Yingying Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- N-Glycan Remodeling on Glucagon Receptor Is an Effector of Nutrient Sensing by the Hexosamine Biosynthesis Pathway
- (2014) Anita Johswich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galectin-9 controls the therapeutic activity of 4-1BB–targeting antibodies
- (2014) Shravan Madireddi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Galectin-9 Increases Tim-3+ Dendritic Cells and CD8+ T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions
- (2014) K. Nagahara et al. JOURNAL OF IMMUNOLOGY
- Galectin-9 Signaling through TIM-3 Is Involved in Neutrophil-Mediated Gram-Negative Bacterial Killing: An Effect Abrogated within the Cystic Fibrosis Lung
- (2014) I. Vega-Carrascal et al. JOURNAL OF IMMUNOLOGY
- The Role of T cell Immunoglobulin and Mucin Domain-3 in Immune Thrombocytopenia
- (2014) X.-M. Zhang et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Ligand binding and complex formation of galectin-3 is modulated by pH variations
- (2013) Tobias von Mach et al. BIOCHEMICAL JOURNAL
- Endothelial LGALS9 splice variant expression in endothelial cell biology and angiogenesis
- (2013) Roy Heusschen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Galectin-9 in tumor biology: A jack of multiple trades
- (2013) Roy Heusschen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Overexpression of Galectin-9 in Islets Prolongs Grafts Survival via Downregulation of Th1 Responses
- (2013) Feng-Cheng Chou et al. CELL TRANSPLANTATION
- Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site
- (2013) Yasuhiro Nonaka et al. JOURNAL OF BIOCHEMISTRY
- Galectin-9 Protein Is Up-regulated in Astrocytes by Tumor Necrosis Factor and Promotes Encephalitogenic T-cell Apoptosis
- (2013) Andrew J. Steelman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galectin-9 plasma levels reflect adverse hematological and immunological features in acute dengue virus infection
- (2013) Haorile Chagan-Yasutan et al. JOURNAL OF CLINICAL VIROLOGY
- Tim-3/Galectin-9 Regulate the Homeostasis of Hepatic NKT Cells in a Murine Model of Nonalcoholic Fatty Liver Disease
- (2013) Z.-H. Tang et al. JOURNAL OF IMMUNOLOGY
- T Cell Ig and Mucin Domain-Containing Protein 3 Is Recruited to the Immune Synapse, Disrupts Stable Synapse Formation, and Associates with Receptor Phosphatases
- (2013) K. L. Clayton et al. JOURNAL OF IMMUNOLOGY
- IL-1 Promotes Antimicrobial Immunity in Macrophages by Regulating TNFR Signaling and Caspase-3 Activation
- (2013) P. Jayaraman et al. JOURNAL OF IMMUNOLOGY
- The Third Dimension of Reading the Sugar Code by Lectins: Design of Glycoclusters with Cyclic Scaffolds as Tools with the Aim to Define Correlations between Spatial Presentation and Activity
- (2013) Paul Murphy et al. MOLECULES
- Adipose tissue-specific modulation of galectin expression in lean and obese mice: Evidence for regulatory function
- (2013) Davina H. Rhodes et al. Obesity
- Galectin-9 Activates and Expands Human T-Helper 1 Cells
- (2013) Marloes J. M. Gooden et al. PLoS One
- Galectin-9-Mediated Protection from Allo-Specific T Cells as a Mechanism of Immune Privilege of Corneal Allografts
- (2013) Machiko Shimmura-Tomita et al. PLoS One
- Galectin-9 Ameliorates Clinical Severity of MRL/lpr Lupus-Prone Mice by Inducing Plasma Cell Apoptosis Independently of Tim-3
- (2013) Masahiro Moritoki et al. PLoS One
- Cis Association of Galectin-9 with Tim-3 Differentially Regulates IL-12/IL-23 Expressions in Monocytes via TLR Signaling
- (2013) Cheng J. Ma et al. PLoS One
- Galectin-9 Is a Suppressor of T and B Cells and Predicts the Immune Modulatory Potential of Mesenchymal Stromal Cell Preparations
- (2013) Christopher Ungerer et al. STEM CELLS AND DEVELOPMENT
- pH-Dependent Recycling of Galectin-3 at the Apical Membrane of Epithelial Cells
- (2013) Tamara Straube et al. TRAFFIC
- Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma
- (2013) María L Bacigalupo WORLD JOURNAL OF GASTROENTEROLOGY
- Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease
- (2013) Yuko Kurose et al. BMC Nephrology
- Galectin-9 induced by dietary synbiotics is involved in suppression of allergic symptoms in mice and humans
- (2012) S. Kivit et al. ALLERGY
- Galectin-9 Acts as a Prognostic Factor with Antimetastatic Potential in Hepatocellular Carcinoma
- (2012) Zhao-Yang Zhang et al. Asian Pacific Journal of Cancer Prevention
- Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection
- (2012) S. Elahi et al. BLOOD
- Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients
- (2012) S. Sanchez-Cuellar et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- HCV-infected hepatocytes drive CD4+CD25+Foxp3+regulatory T-cell development through the Tim-3/Gal-9 pathway
- (2012) Xiao J. Ji et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Adhesion/growth-regulatory galectins in the human eye: localization profiles and tissue reactivities as a standard to detect disease-associated alterations
- (2012) Ursula Schlötzer-Schrehardt et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway
- (2012) Rodrigo Liberal et al. HEPATOLOGY
- The Tim3-Galectin 9 Pathway Induces Antibacterial Activity in Human Macrophages Infected with Mycobacterium tuberculosis
- (2012) I. Sada-Ovalle et al. JOURNAL OF IMMUNOLOGY
- The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells
- (2012) Valerie R. Wiersma et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Controls Herpes Simplex Virus-Induced Immunoinflammatory Lesions
- (2012) P. B. J Reddy et al. JOURNAL OF VIROLOGY
- Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4+CD25low/int Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number
- (2012) Kun Lv et al. PLoS One
- Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection
- (2012) Gaia Nebbia et al. PLoS One
- Rapid Decrease of Plasma Galectin-9 Levels in Patients with Acute HIV Infection after Therapy
- (2012) Hiroki Saitoh et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses
- (2012) Clément Barjon et al. Infectious Agents and Cancer
- Galectins as self/non-self recognition receptors in innate and adaptive immunity: an unresolved paradox
- (2012) Gerardo R. Vasta et al. Frontiers in Immunology
- Expression of galectin-9 by IFN-γ stimulated human nasal polyp fibroblasts through MAPK, PI3K, and JAK/STAT signaling pathways
- (2011) Won Sun Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Tim-3 ligand galectin-9 reduces IL-17 level and accelerates Klebsiella pneumoniae infection
- (2011) Feng Wang et al. CELLULAR IMMUNOLOGY
- Galectin-9 and T Cell Immunoglobulin Mucin-3 Pathway Is a Therapeutic Target for Type 1 Diabetes
- (2011) Motoko Kanzaki et al. ENDOCRINOLOGY
- Galectin-9 Protein Expression in Endothelial Cells Is Positively Regulated by Histone Deacetylase 3
- (2011) Saydul Alam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways
- (2011) I. Vega-Carrascal et al. JOURNAL OF IMMUNOLOGY
- Influence of Galectin-9/Tim-3 Interaction on Herpes Simplex Virus-1 Latency
- (2011) P. B. J. Reddy et al. JOURNAL OF IMMUNOLOGY
- Therapeutic potential of Galectin-9 in human disease
- (2011) Valerie R. Wiersma et al. MEDICINAL RESEARCH REVIEWS
- Increased expression of distinct galectins in multiple sclerosis lesions
- (2011) M. Stancic et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses
- (2011) S. Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry
- (2011) S. Bi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sphingosine 1-phosphate in coagulation and inflammation
- (2011) Hideru Obinata et al. Seminars in Immunopathology
- Galectin-9 induces osteoblast differentiation through the CD44/Smad signaling pathway
- (2010) Rena Tanikawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis
- (2010) Kazuki Sakai et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- N-domain of human adhesion/growth-regulatory galectin-9: Preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution
- (2010) Dolores Solís et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- X-ray Structures of Human Galectin-9 C-terminal Domain in Complexes with a Biantennary Oligosaccharide and Sialyllactose
- (2010) Hiromi Yoshida et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
- (2010) Kaori Sakuishi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways
- (2010) T Kobayashi et al. LEUKEMIA
- SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies
- (2010) Elin Gustavsson et al. Molecular Cancer
- Targeting Activating Transcription Factor 3 by Galectin-9 Induces Apoptosis and Overcomes Various Types of Treatment Resistance in Chronic Myelogenous Leukemia
- (2010) J. Kuroda et al. MOLECULAR CANCER RESEARCH
- A Crucial Role for Kupffer Cell-Derived Galectin-9 in Regulation of T Cell Immunity in Hepatitis C Infection
- (2010) John A. Mengshol et al. PLoS One
- Galectin-9 trafficking regulates apical-basal polarity in Madin–Darby canine kidney epithelial cells
- (2010) Rashmi Mishra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Galectin-9 accelerates transforming growth factor β3-induced differentiation of human mesenchymal stem cells to chondrocytes
- (2009) Tomohiro Arikawa et al. BONE
- Galectin-9 expands immunosuppressive macrophages to ameliorate T-cell-mediated lung inflammation
- (2009) Tomohiro Arikawa et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Intracellular galectin-9 activates inflammatory cytokines in monocytes
- (2009) Ai Matsuura et al. GENES TO CELLS
- Galectin-9 Is a High Affinity IgE-binding Lectin with Anti-allergic Effect by Blocking IgE-Antigen Complex Formation
- (2009) Toshiro Niki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Subcellular targeting strategies for drug design and delivery
- (2009) Lawrence Rajendran et al. NATURE REVIEWS DRUG DISCOVERY
- A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death
- (2009) N. G. Than et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Galectin Profile of the Endothelium
- (2008) Victor L. Thijssen et al. AMERICAN JOURNAL OF PATHOLOGY
- Role of gastrointestinal eosinophils in inflammatory bowel disease and intestinal tumours
- (2008) Jochen Wedemeyer et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
- Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells
- (2008) J. Klibi et al. BLOOD
- Expression and Localization of Galectin-9 in the Human Uterodome
- (2008) Yuji SHIMIZU et al. ENDOCRINE JOURNAL
- Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain
- (2008) M. Nagae et al. GLYCOBIOLOGY
- Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices
- (2008) A. Nobumoto et al. GLYCOBIOLOGY
- Galectin-9 expression links to malignant potential of cervical squamous cell carcinoma
- (2008) Meiyan Liang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Different roles of galectin-9 isoforms in modulating E-selectin expression and adhesion function in LoVo colon carcinoma cells
- (2008) Feng Zhang et al. MOLECULAR BIOLOGY REPORTS
- Structural Analysis of the Human Galectin-9 N-terminal Carbohydrate Recognition Domain Reveals Unexpected Properties that Differ from the Mouse Orthologue
- (2007) Masamichi Nagae et al. JOURNAL OF MOLECULAR BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More