The Role of T cell Immunoglobulin and Mucin Domain-3 in Immune Thrombocytopenia

Lack of TIM-3 Immunoregulation in Multiple Sclerosis

(2014) L. Yang et al.   JOURNAL OF IMMUNOLOGY

Impaired Expression of Tim-3 on Th17 and Th1 Cells in Psoriasis

(2013) Y Kanai et al.   ACTA DERMATO-VENEREOLOGICA

Cellular immune dysfunction in immune thrombocytopenia (ITP)

(2013) Christopher G. J. McKenzie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Th17 cell development: from the cradle to the grave

(2013) Luis A. Zúñiga et al.   IMMUNOLOGICAL REVIEWS

The serum levels of the cytokines involved in the Th17 and Th1 cell commitment are increased in individuals with borderline thrombocytopenia

(2013) Andreia Maria Camargos Rocha et al.   Journal of Hematology & Oncology

T Cell Ig Mucin-3 Promotes Homeostasis of Sepsis by Negatively Regulating the TLR Response

(2013) X. Yang et al.   JOURNAL OF IMMUNOLOGY

The Influence of T Cell Ig Mucin-3 Signaling on Central Nervous System Autoimmune Disease Is Determined by the Effector Function of the Pathogenic T Cells

(2013) S. Y. Lee et al.   JOURNAL OF IMMUNOLOGY

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection

(2013) Stephanie Jost et al.   Retrovirology

Immune Dysregulation in Immune Thrombocytopenia

(2013) Karina Yazdanbakhsh et al.   SEMINARS IN HEMATOLOGY

Innate and Adaptive Immunity in Immune Thrombocytopenia

(2013) Alan H. Lazarus et al.   SEMINARS IN HEMATOLOGY

CD4+CD25+Foxp3+ Regulatory T Cells in the Pathophysiology of Immune Thrombocytopenia

(2013) Tetsuya Nishimoto et al.   SEMINARS IN HEMATOLOGY

Decreased expression of indoleamine 2,3-dioxygenase 1 in dendritic cells contributes to impaired regulatory T cell development in immune thrombocytopenia

(2012) Lucia Catani et al.   ANNALS OF HEMATOLOGY

The immunopathogenesis of immune thrombocytopenia

(2012) John W. Semple et al.   CURRENT OPINION IN HEMATOLOGY

Blockade of Tim-3 signaling restores the virus-specific CD8+T-cell response in patients with chronic hepatitis B

(2012) Wei Wu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune checkpoints in central nervous system autoimmunity

(2012) Nicole Joller et al.   IMMUNOLOGICAL REVIEWS

Tim-3 Pathway Controls Regulatory and Effector T Cell Balance during Hepatitis C Virus Infection

(2012) J. P. Moorman et al.   JOURNAL OF IMMUNOLOGY

Direct and Indirect Regulatory Mechanisms in TH17 cell Differentiation and Functions

(2012) Y. Bi et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Tim-3 regulates pro- and anti-inflammatory cytokine expression in human CD14+ monocytes

(2011) Ying Zhang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Isotype of Autoantibodies Influences the Phagocytosis of Antibody-Coated Platelets in Autoimmune Thrombocytopenic Purpura

(2011) M. Hoemberg et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

In vitro recovery of Th1/Th2 balance in PBMCs from patients with immune thrombocytopenia through the actions of IL-18BPa/Fc

(2011) Ning-ning Shan et al.   THROMBOSIS RESEARCH

Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents

(2010) W. Bao et al.   BLOOD

Tim3 binding to galectin-9 stimulates antimicrobial immunity

(2010) Pushpa Jayaraman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

(2009) M. Nakayama et al.   BLOOD

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

(2009) William D. Hastings et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Th17-like developmental process leads to CD8+Tc17 cells with reduced cytotoxic activity

(2009) Magdalena Huber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Elevated profile of Th17, Th1 and Tc1 cells in patients with immune thrombocytopenic purpura

(2009) J. Zhang et al.   HAEMATOLOGICA

The role of T-cell immunoglobulin- and mucin-domain-containing molecule-3 polymorphisms in idiopathic thrombocytopenic purpura

(2009) Wei Ting Du et al.   HUMAN IMMUNOLOGY

The costimulatory role of TIM molecules

(2009) Roselynn Rodriguez-Manzanet et al.   IMMUNOLOGICAL REVIEWS

Elevated Interleukin-21 Correlated to Th17 and Th1 Cells in Patients with Immune Thrombocytopenia

(2009) Xiaojuan Zhu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Interleukin 18 and interleukin 18 binding protein in patients with idiopathic thrombocytopenic purpura

(2008) Ning-ning Shan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Increased cytotoxic T-lymphocyte-mediated cytotoxicity predominant in patients with idiopathic thrombocytopenic purpura without platelet autoantibodies

(2008) C. Zhao et al.   HAEMATOLOGICA

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells

(2008) Feng Wang et al.   IMMUNOBIOLOGY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Splenic macrophages maintain the anti-platelet autoimmune response via uptake of opsonized platelets in patients with immune thrombocytopenic purpura

(2008) M. KUWANA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS