Multistep synthesis and screening of heterocyclic tetrads containing furan, pyrazoline, thiazole and triazole (or oxadiazole) as antimicrobial and anticancer agents

Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

(2021) Ashok Babu Kasetti et al.   MOLECULES

Design, synthesis, and biological evaluation of novel bromo-pyrimidine analogues as tyrosine kinase inhibitors

(2021) Chandrashekar S. Munikrishnappa et al.   Arabian Journal of Chemistry

A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies

(2021) Santosh Kumar Verma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An update of new small-molecule anticancer drugs approved from 2015 to 2020

(2021) Xiaoxia Liang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2D-Quantitative structure activity relationship (QSAR) modeling, docking studies, synthesis and in-vitro evaluation of 1,3,4-thiadiazole tethered coumarin derivatives as antiproliferative agents

(2021) Natarajan Ramalakshmi et al.   Journal of Saudi Chemical Society

Synthetic and Naturally Occurring Heterocyclic Anticancer Compounds with Multiple Biological Targets

(2021) Richard Kwamla Amewu et al.   MOLECULES

Assessment of the Antimicrobial and Antiproliferative Activities of Chloropyrazine-Tethered Pyrimidine Derivatives: In Vitro, Molecular Docking, and In-Silico Drug-Likeness Studies

(2021) Richie R. Bhandare et al.   Applied Sciences-Basel

Antimicrobial, Antioxidant, and Anticancer Activities of Some Novel Isoxazole Ring Containing Chalcone and Dihydropyrazole Derivatives

(2020) Afzal Shaik et al.   MOLECULES

Design, Facile Synthesis and Characterization of Dichloro Substituted Chalcones and Dihydropyrazole Derivatives for Their Antifungal, Antitubercular and Antiproliferative Activities

(2020) Afzal B. Shaik et al.   MOLECULES

Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

(2020) Afzal B. Shaik et al.   Arabian Journal of Chemistry

Novel Pyrimidine Derivatives from 2,5-Dichloro-3-acetylthienyl Chalcones as Antifungal, Antitubercular and Cytotoxic Agents: Design, Synthesis, Biological Activity and Docking Study

(2019) BONTHA VENKATA SUBRAHMANYA LOKESH et al.   ASIAN JOURNAL OF CHEMISTRY

Modern advances in heterocyclic chemistry in drug discovery

(2016) Alexandria P. Taylor et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Heterocyclic Scaffolds: Centrality in Anticancer Drug Development

(2015) Imran Ali et al.   CURRENT DRUG TARGETS

Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle

(2015) Demetrio Raffa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Current Approaches for Enhanced Expression of Secondary Metabolites as Bioactive Compounds in Plants for Agronomic and Human Health Purposes – a Review

(2014) Sandra N. Jimenez-Garcia et al.   POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES

Synthesis, in vitro antifungal activity and in silico study of 3-(1,2,4-triazol-1-yl)flavanones

(2013) Saeed Emami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Heterocycles in drugs and drug discovery

(2012) A. Gomtsyan   Chemistry of Heterocyclic Compounds

Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents

(2011) Peng-Cheng Lv et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of some novel 2-substituted-5-[isopropylthiazole] clubbed 1,2,4-triazole and 1,3,4-oxadiazoles as potential antimicrobial and antitubercular agents

(2010) G.V. Suresh Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY