2D-Quantitative structure activity relationship (QSAR) modeling, docking studies, synthesis and in-vitro evaluation of 1,3,4-thiadiazole tethered coumarin derivatives as antiproliferative agents

Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study

(2017) Magda A.-A. El-Sayed et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

QSAR models of antiproliferative activity of imidazo[2,1-b][1,3,4]thiadiazoles in various cancer cell lines

(2016) Joanna Matysiak et al.   MOLECULAR DIVERSITY

Synthesis and anticancer activity of novel 3,6-disubstituted 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives

(2016) Georgios Charitos et al.   Arabian Journal of Chemistry

Synthesis and anti-inflammatory activity of some new 1,3,4-thiadiazoles containing pyrazole and pyrrole nucleus

(2016) S. Maddila et al.   Journal of Saudi Chemical Society

Systemic Therapy for Stage IV Non–Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update

(2015) Gregory A. Masters et al.   JOURNAL OF CLINICAL ONCOLOGY

Modern 2D QSAR for drug discovery

(2014) Richard A. Lewis et al.   Wiley Interdisciplinary Reviews-Computational Molecular Science

Some case studies on application of “rm2” metrics for judging quality of quantitative structure-activity relationship predictions: Emphasis on scaling of response data

(2013) Kunal Roy et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

QSAR, docking and in vivo studies for immunomodulatory activity of isolated triterpenoids from Eucalyptus tereticornis and Gentiana kurroo

(2012) Anupam Maurya et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

On Various Metrics Used for Validation of Predictive QSAR Models with Applications in Virtual Screening and Focused Library Design

(2011) Kunal Roy et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

QSAR Models for CXCR2 Receptor Antagonists Based on the Genetic Algorithm for Data Preprocessing Prior to Application of the PLS Linear Regression Method and Design of the New Compounds Using In Silico Virtual Screening

(2011) Tahereh Asadollahi et al.   MOLECULES

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

(2010) Makoto Maemondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-throughput andin silicoscreenings in drug discovery

(2009) Sharangdhar S Phatak et al.   Expert Opinion on Drug Discovery

Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl]- and 1-[5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines

(2008) Mina Behrouzi-Fardmoghadam et al.   BIOORGANIC & MEDICINAL CHEMISTRY