Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation
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Title
Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation
Authors
Keywords
Amyloid, Angiotensin, Angiotensin-converting enzyme, Cardiovascular, Coronavirus, COVID, Neprilysin, Renin-angiotensin system, SARS, Vasopeptidase
Journal
PEPTIDES
Volume 151, Issue -, Pages 170766
Publisher
Elsevier BV
Online
2022-02-11
DOI
10.1016/j.peptides.2022.170766
References
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Note: Only part of the references are listed.- Kinins and Chymase: The Forgotten Components of the Renin angiotensin system and their implications in COVID-19 Disease
- (2021) Zaid Abassi et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier?
- (2021) Susan M. Burks et al. BRAIN BEHAVIOR AND IMMUNITY
- A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection
- (2021) Cornelia Blume et al. NATURE GENETICS
- Neuro-COVID-19 is more than anosmia
- (2021) Finja Schweitzer et al. CURRENT OPINION IN NEUROLOGY
- Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex
- (2021) Alberto Bartolomé et al. Scientific Reports
- COVID-19—A Theory of Autoimmunity Against ACE-2 Explained
- (2021) Philip McMillan et al. Frontiers in Immunology
- Brain Renin–Angiotensin System as Novel and Potential Therapeutic Target for Alzheimer’s Disease
- (2021) Raúl Loera-Valencia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis?
- (2021) Sandra M. Gonzalez et al. Frontiers in Immunology
- Epigenetic Mechanisms Underlying COVID-19 Pathogenesis
- (2021) Syuzo Kaneko et al. Biomedicines
- Dysregulation of ACE (Angiotensin-Converting Enzyme)-2 and Renin-Angiotensin Peptides in SARS-CoV-2 Mediated Mortality and End-Organ Injuries
- (2021) Kaiming Wang et al. HYPERTENSION
- Angiotensin-(1–7) reduces α-synuclein aggregation by enhancing autophagic activity in Parkinson’s disease
- (2021) You-Yong Tian et al. Neural Regeneration Research
- ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
- (2021) Tomokazu Yamaguchi et al. Nature Communications
- Integrin activation is an essential component of SARS-CoV-2 infection
- (2021) Peter Simons et al. Scientific Reports
- Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites
- (2021) Thomas L. Williams et al. Scientific Reports
- Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility
- (2021) Anissa Viveiros et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease
- (2020) Charles E. Evans et al. ACTA NEUROPATHOLOGICA
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction
- (2020) Takafumi Minato et al. Nature Communications
- A potential role for integrins in host cell entry by SARS-CoV-2
- (2020) Christian JA Sigrist et al. ANTIVIRAL RESEARCH
- Targeting Neprilysin (NEP) pathways: A potential new hope to defeat COVID-19 ghost
- (2020) Manar Mohammed El Tabaa et al. BIOCHEMICAL PHARMACOLOGY
- Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
- (2020) Vanessa Monteil et al. CELL
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- The potential role of the Carotid Body in COVID-19
- (2020) Andrea Porzionato et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
- (2020) David H. Brann et al. Science Advances
- Interaction between the apelinergic system and ACE2 in the cardiovascular system: therapeutic implications
- (2020) Paulami Chatterjee et al. CLINICAL SCIENCE
- Brain angiotensin converting enzyme-2 in central cardiovascular regulation
- (2020) Mazher Mohammed et al. CLINICAL SCIENCE
- Discovery and characterization of ACE2 – a 20-year journey of surprises from vasopeptidase to COVID-19
- (2020) Nigel M. Hooper et al. CLINICAL SCIENCE
- Elevated ACE-2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication
- (2020) Mengfei Chen et al. EUROPEAN RESPIRATORY JOURNAL
- Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus
- (2020) Tasnim BEACON et al. GENOME
- Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor
- (2020) Olusegun O. Onabajo et al. NATURE GENETICS
- ACE2 and SCARF expression in human dorsal root ganglion nociceptors: implications for SARS-CoV-2 virus neurological effects
- (2020) Stephanie Shiers et al. PAIN
- ACE2: from protection of liver disease to propagation of COVID-19
- (2020) Fiona J. Warner et al. CLINICAL SCIENCE
- ACE2, a multifunctional protein – from cardiovascular regulation to COVID-19
- (2020) Michael Bader et al. CLINICAL SCIENCE
- The Role of Angiotensin Converting Enzyme 2 in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection
- (2020) Josef M. Penninger et al. GASTROENTEROLOGY
- The Rationale for Angiotensin Receptor Neprilysin Inhibitors in a Multi-Targeted Therapeutic Approach to COVID-19
- (2020) Alessandro Bellis et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neprilysin expression and functions in development, ageing and disease
- (2020) NN Nalivaeva et al. MECHANISMS OF AGEING AND DEVELOPMENT
- SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
- (2020) Lizhou Zhang et al. Nature Communications
- ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors
- (2020) Zofia Wicik et al. Journal of Clinical Medicine
- Targeting amyloid clearance in Alzheimer's disease as a therapeutic strategy
- (2019) Natalia N. Nalivaeva et al. BRITISH JOURNAL OF PHARMACOLOGY
- Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration
- (2018) Chhinder P. Sodhi et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response
- (2018) Friederike Klempin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
- (2018) Robson Augusto Souza Santos et al. PHYSIOLOGICAL REVIEWS
- miRNA-200c-3p is crucial in acute respiratory distress syndrome
- (2017) Qiang Liu et al. Cell Discovery
- Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors
- (2016) Lei Wang et al. NEUROPHARMACOLOGY
- Angiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology
- (2016) Patrick Gavin Kehoe et al. Alzheimers Research & Therapy
- Angiotensin‐Converting Enzyme 3 (ACE3) Protects Against Pressure Overload‐Induced Cardiac Hypertrophy
- (2016) Chang‐Jiang Yu et al. Journal of the American Heart Association
- Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis
- (2015) Jean Kaoru Millet et al. VIRUS RESEARCH
- Production of soluble Neprilysin by endothelial cells
- (2014) Sanjaya Kuruppu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Angiotensin-converting enzyme 2 is subject to post-transcriptional regulation bymiR-421
- (2014) Daniel W. Lambert et al. CLINICAL SCIENCE
- Angiotensin-Converting Enzyme 2–Independent Action of Presumed Angiotensin-Converting Enzyme 2 Activators
- (2014) Philipp K. Haber et al. HYPERTENSION
- Conversion of Aβ43 to Aβ40 by the successive action of angiotensin-converting enzyme 2 and angiotensin-converting enzyme
- (2014) Shuyu Liu et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Epigenetic regulation of angiotensin-converting enzyme 2 (ACE2) by SIRT1 under conditions of cell energy stress
- (2013) Nicola E. Clarke et al. CLINICAL SCIENCE
- Apelin is a positive regulator of ACE2 in failing hearts
- (2013) Teruki Sato et al. JOURNAL OF CLINICAL INVESTIGATION
- Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS
- (2013) Vaibhav B. Patel et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein
- (2013) A. Heurich et al. JOURNAL OF VIROLOGY
- ACE2 – From the renin–angiotensin system to gut microbiota and malnutrition
- (2013) Thomas Perlot et al. MICROBES AND INFECTION
- ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
- (2012) Tatsuo Hashimoto et al. NATURE
- Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling
- (2012) Nicola E. Clarke et al. PLoS One
- Nuclear signalling by membrane protein intracellular domains: The AICD enigma
- (2011) Caroline Beckett et al. CELLULAR SIGNALLING
- Collectrin and ACE2 in renal and intestinal amino acid transport
- (2011) Dustin Singer et al. Channels
- The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway
- (2010) Nikolai D. Belyaev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and Disruption of Sperm-Specific Angiotensin Converting Enzyme-3 (ACE3) in Mouse
- (2010) Naokazu Inoue et al. PLoS One
- Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships
- (2009) Nicholas D Bland et al. BMC EVOLUTIONARY BIOLOGY
- Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor
- (2009) K. Wu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insight into the substrate length restriction of M32 carboxypeptidases: Characterization of two distinct subfamilies
- (2009) Marianne M. Lee et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease
- (2008) Nikolai D Belyaev et al. EMBO REPORTS
- Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents
- (2008) José A. Hernández Prada et al. HYPERTENSION
- Angiotensin-converting enzyme 2 in the brain: properties and future directions
- (2008) Huijing Xia et al. JOURNAL OF NEUROCHEMISTRY
- Endocytosis of the receptor-binding domain of SARS-CoV spike protein together with virus receptor ACE2
- (2008) Shunxin Wang et al. VIRUS RESEARCH
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