FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity

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No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor

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High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages

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SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

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Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein

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Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

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Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

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Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures

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Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

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An inflammatory cytokine signature predicts COVID-19 severity and survival

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Succination inactivates gasdermin D and blocks pyroptosis

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COVID-19-neutralizing antibodies predict disease severity and survival

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Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages

(2020) Xiang Song et al.   CYTOMETRY PART A

Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

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Severe Acute Respiratory Syndrome Coronavirus 2–Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells

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REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19

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Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

(2020) Mads Delbo Larsen et al.   SCIENCE

Human NLRP1 is a sensor for double-stranded RNA

(2020) Stefan Bauernfried et al.   SCIENCE

Dynamic changes in anti-SARS-CoV-2 antibodies during SARS-CoV-2 infection and recovery from COVID-19

(2020) Kening Li et al.   Nature Communications

Detection of viruses by inflammasomes

(2020) Lotte Spel et al.   Current Opinion in Virology

Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation

(2019) Michael A. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

(2019) Corey Rogers et al.   Nature Communications

A Novel, Five-Marker Alternative to CD16–CD14 Gating to Identify the Three Human Monocyte Subsets

(2019) Siew-Min Ong et al.   Frontiers in Immunology

Inflammasome signaling and regulation of interleukin-1 family cytokines

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