SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation
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Title
SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-02
DOI
10.1038/s41467-021-25015-6
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Note: Only part of the references are listed.- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
- (2020) Qun Li et al. NEW ENGLAND JOURNAL OF MEDICINE
- The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
- (2020) Nature Microbiology
- Identification of a novel coronavirus causing severe pneumonia in human
- (2020) Li-Li Ren et al. CHINESE MEDICAL JOURNAL
- Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals
- (2020) Ling Ni et al. IMMUNITY
- Clinical and immunological features of severe and moderate coronavirus disease 2019
- (2020) Guang Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- The many faces of the anti-COVID immune response
- (2020) Santosha A. Vardhana et al. JOURNAL OF EXPERIMENTAL MEDICINE
- COVID-19: consider cytokine storm syndromes and immunosuppression
- (2020) Puja Mehta et al. LANCET
- SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells
- (2020) Jingfang Mu et al. Science China-Life Sciences
- Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis
- (2020) Derek K Chu et al. LANCET
- SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects
- (2020) Antoni G. Wrobel et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Overview: Systemic Inflammatory Response Derived From Lung Injury Caused by SARS-CoV-2 Infection Explains Severe Outcomes in COVID-19
- (2020) Rafael B. Polidoro et al. Frontiers in Immunology
- Structures of the SARS ‐CoV‐2 nucleocapsid and their perspectives for drug design
- (2020) Ya Peng et al. EMBO JOURNAL
- Inflammasome formation in the lungs of patients with fatal COVID-19
- (2020) Stefano Toldo et al. INFLAMMATION RESEARCH
- Tackling the cytokine storm in COVID-19, challenges and hopes
- (2020) Shifaa M. Abdin et al. LIFE SCIENCES
- Origin and cross-species transmission of bat coronaviruses in China
- (2020) Alice Latinne et al. Nature Communications
- Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients
- (2020) Tamara S. Rodrigues et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cullin1 binds and promotes NLRP3 ubiquitination to repress systematic inflammasome activation
- (2019) Pin Wan et al. FASEB JOURNAL
- Severe Acute Respiratory Syndrome Coronavirus Viroporin 3a Activates the NLRP3 Inflammasome
- (2019) I-Yin Chen et al. Frontiers in Microbiology
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
- (2019) Humayun Sharif et al. NATURE
- Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation to Induce Vascular Leakage in Mice
- (2019) Pan Pan et al. JOURNAL OF VIROLOGY
- Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle
- (2019) Yingying Cong et al. JOURNAL OF VIROLOGY
- Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage
- (2019) Pan Pan et al. Frontiers in Microbiology
- Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion
- (2018) Wenbiao Wang et al. Nature Communications
- Targeting the NLRP3 inflammasome in inflammatory diseases
- (2018) Matthew S. J. Mangan et al. NATURE REVIEWS DRUG DISCOVERY
- The caspase-1 inhibitor AC-YVAD-CMK attenuates acute gastric injury in mice: involvement of silencing NLRP3 inflammasome activities
- (2016) Fang Zhang et al. Scientific Reports
- IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections
- (2016) Jeroen Slaats et al. PLoS Pathogens
- Inflammasome activation and function in liver disease
- (2015) Gyongyi Szabo et al. Nature Reviews Gastroenterology & Hepatology
- Interleukin-1 function and role in rheumatic disease
- (2015) Georg Schett et al. Nature Reviews Rheumatology
- Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome
- (2015) Jose L. Nieto-Torres et al. VIROLOGY
- RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
- (2014) Xiaqiong Wang et al. NATURE IMMUNOLOGY
- Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4
- (2013) N. Kayagaki et al. SCIENCE
- The NLRP3 inflammasome activation in human or mouse cells, sensitivity causes puzzle
- (2013) Hongbin Wang et al. Protein & Cell
- Interleukin-1 (IL-1 ) Processing Pathway
- (2010) A. Weber et al. Science Signaling
- Interleukin-1 (IL-1) Pathway
- (2010) A. Weber et al. Science Signaling
- The Inflammasomes: Guardians of the Body
- (2009) Fabio Martinon et al. Annual Review of Immunology
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