Multidisciplinary approaches for elucidating genetics and molecular pathogenesis of urinary tract malformations

Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux

(2021) Miguel Verbitsky et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeted Single-Cell RNA-seq Identifies Minority Cell Types of Kidney Distal Nephron

(2021) Lihe Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulatory genomic circuitry of human disease loci by integrative epigenomics

(2021) Carles A. Boix et al.   NATURE

Chromatin Regulation in Development: Current Understanding and Approaches

(2021) Zi Hao Zheng et al.   Stem Cells International

Genetic Testing in Pediatric Kidney Disease

(2020) Veronica Arora et al.   INDIAN JOURNAL OF PEDIATRICS

Mouse Embryonic Stem Cell-Derived Ureteric Bud Progenitors Induce Nephrogenesis

(2020) Zenglai Tan et al.   Cells

Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits

(2020) Lindsey K. Stolze et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Clinical Integration of Genome Diagnostics for Congenital Anomalies of the Kidney and Urinary Tract

(2020) Rik Westland et al.   Clinical Journal of the American Society of Nephrology

Human and mouse studies establish TBX6 in Mendelian CAKUT and as a potential driver of kidney defects associated with the 16p11.2 microdeletion syndrome

(2020) Nan Yang et al.   KIDNEY INTERNATIONAL

Transcript expression-aware annotation improves rare variant interpretation

(2020) Beryl B. Cummings et al.   NATURE

Using Genetic and Species Diversity to Tackle Kidney Disease

(2020) Michael R. Garrett et al.   TRENDS IN GENETICS

Copy number variations associated with fetal congenital kidney malformations

(2020) Meiying Cai et al.   Molecular Cytogenetics

Molecular diagnostic in fetuses with isolated congenital anomalies of the kidney and urinary tract by whole‐exome sequencing

(2020) Xiaoyan Zhou et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids

(2020) Shohei Kuraoka et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Long-read human genome sequencing and its applications

(2020) Glennis A. Logsdon et al.   NATURE REVIEWS GENETICS

In vitro induction and in vivo engraftment of kidney organoids derived from human pluripotent stem cells

(2020) Denglu Zhang et al.   Experimental and Therapeutic Medicine

Differentiating Induced Pluripotent Stem Cells into Renal Cells: A New Approach to Treat Kidney Diseases

(2020) Patrícia de Carvalho Ribeiro et al.   Stem Cells International

A novel ADPKD model using kidney organoids derived from disease-specific human iPSCs

(2020) Tatsuya Shimizu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differentiation of a Contractile, Ureter-Like Tissue, from Embryonic Stem Cell–Derived Ureteric Bud and Ex Fetu Mesenchyme

(2020) May Sallam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

(2020) Sara E. Howden et al.   Cell Stem Cell

New gene discoveries highlight functional convergence in autism and related neurodevelopmental disorders

(2020) Mariana Moyses-Oliveira et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies

(2019) Tahir N. Khan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

(2019) Mazène Hochane et al.   PLOS BIOLOGY

Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction

(2019) Caroline M. Kolvenbach et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Iceberg under Water: Unexplored Complexity of Chromoanagenesis in Congenital Disorders

(2019) Cinthya J. Zepeda-Mendoza et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion

(2019) Marie Alice Dupont et al.   HUMAN MOLECULAR GENETICS

Missing heritability of complex diseases: case solved?

(2019) Emmanuelle Génin   HUMAN GENETICS

Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases

(2019) M Adela Mansilla et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids

(2019) Jaap Mulder et al.   PEDIATRIC RESEARCH

Genetic regulatory variation in populations informs transcriptome analysis in rare disease

(2019) Pejman Mohammadi et al.   SCIENCE

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

(2019) Ayshwarya Subramanian et al.   Nature Communications

Regulatory variants: from detection to predicting impact

(2018) Elena Rojano et al.   BRIEFINGS IN BIOINFORMATICS

Genetic basis of human congenital anomalies of the kidney and urinary tract

(2018) Simone Sanna-Cherchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Zebrafish as a model for kidney function and disease

(2018) Priya Outtandy et al.   PEDIATRIC NEPHROLOGY

Impact of next generation sequencing on our understanding of CAKUT

(2018) Anukrati Nigam et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Genetic Renal Diseases: The Emerging Role of Zebrafish Models

(2018) Mohamed Elmonem et al.   Cells

Current epidemiology and antenatal presentation of posterior urethral valves: Outcome of BAPS CASS National Audit

(2018) Ewan Brownlee et al.   JOURNAL OF PEDIATRIC SURGERY

The copy number variation landscape of congenital anomalies of the kidney and urinary tract

(2018) Miguel Verbitsky et al.   NATURE GENETICS

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

(2017) María Santos et al.   GENETICS IN MEDICINE

Long-read genome sequencing identifies causal structural variation in a Mendelian disease

(2017) Jason D Merker et al.   GENETICS IN MEDICINE

Recent Advances in Experimental Whole Genome Haplotyping Methods

(2017) Mengting Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetics of Congenital Anomalies of the Kidney and Urinary Tract: The Current State of Play

(2017) Valentina Capone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeted Exome Sequencing IdentifiesPBX1as Involved in Monogenic Congenital Anomalies of the Kidney and Urinary Tract

(2017) Laurence Heidet et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Novel Insights into the Pathogenesis of Monogenic Congenital Anomalies of the Kidney and Urinary Tract

(2017) Amelie T. van der Ven et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling

(2017) Asaf Vivante et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The promise of single-cell RNA sequencing for kidney disease investigation

(2017) Haojia Wu et al.   KIDNEY INTERNATIONAL

Mortality risk disparities in children receiving chronic renal replacement therapy for the treatment of end-stage renal disease across Europe: an ESPN-ERA/EDTA registry analysis

(2017) Nicholas C Chesnaye et al.   LANCET

Copy-number variation analysis in familial nonsyndromic congenital anomalies of the kidney and urinary tract: Evidence for the causative role of a transposable element-associated genomic rearrangement

(2017) Ekaterini Siomou et al.   Molecular Medicine Reports

Genetic Drivers of Kidney Defects in the DiGeorge Syndrome

(2017) Esther Lopez-Rivera et al.   NEW ENGLAND JOURNAL OF MEDICINE

A brief review of kidney development, maturation, developmental abnormalities, and drug toxicity: juvenile animal relevancy

(2017) John Curtis Seely   Journal of Toxicologic Pathology

Mapping and phasing of structural variation in patient genomes using nanopore sequencing

(2017) Mircea Cretu Stancu et al.   Nature Communications

Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia

(2016) Nikhita Ajit Bolar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Growing Kidney Tissue from Stem Cells: How Far from “Party Trick” to Medical Application?

(2016) Melissa H. Little   Cell Stem Cell

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

(2016) Zhongwei Li et al.   Cell Stem Cell

Sex and gender differences in chronic kidney disease: progression to end-stage renal disease and haemodialysis

(2016) G. Cobo et al.   CLINICAL SCIENCE

Pluripotent stem cell-derived kidney organoids: An in vivo-like in vitro technology

(2016) Frans Schutgens et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene

(2016) Mir Reza Bekheirnia et al.   GENETICS IN MEDICINE

Mutations inC8ORF37cause Bardet Biedl syndrome (BBS21)

(2016) Elise Heon et al.   HUMAN MOLECULAR GENETICS

Exome Sequencing Discerns Syndromes in Patients from Consanguineous Families with Congenital Anomalies of the Kidneys and Urinary Tract

(2016) Asaf Vivante et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Genetic Landscape of Renal Complications in Type 1 Diabetes

(2016) Niina Sandholm et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Prioritization and burden analysis of rare variants in 208 candidate genes suggest they do not play a major role in CAKUT

(2016) Nayia Nicolaou et al.   KIDNEY INTERNATIONAL

Incidence and Risks of Congenital Anomalies of Kidney and Urinary Tract in Newborns

(2016) You-Lin Tain et al.   MEDICINE

Maternal obesity is associated with congenital anomalies of the kidney and urinary tract in offspring

(2016) Ian Macumber et al.   PEDIATRIC NEPHROLOGY

Genetic link between renal birth defects and congenital heart disease

(2016) Jovenal T. San Agustin et al.   Nature Communications

DNA copy number variants: A potentially useful predictor of early onset renal failure in boys with posterior urethral valves

(2016) A. Faure et al.   Journal of Pediatric Urology

The Evolving Diagnostic and Genetic Landscapes of Autism Spectrum Disorder

(2016) Mark N. Ziats et al.   Frontiers in Genetics

Generation of kidney tubular organoids from human pluripotent stem cells

(2016) Shintaro Yamaguchi et al.   Scientific Reports

HapCol: accurate and memory-efficient haplotype assembly from long reads

(2015) Yuri Pirola et al.   BIOINFORMATICS

Genetic Basis of Ureterocele

(2015) Karin Schultz et al.   CURRENT GENOMICS

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish

(2015) Izabella Baranowska Körberg et al.   HUMAN MOLECULAR GENETICS

Non-coding genetic variants in human disease: Figure 1.

(2015) Feng Zhang et al.   HUMAN MOLECULAR GENETICS

Genomic imbalances in pediatric patients with chronic kidney disease

(2015) Miguel Verbitsky et al.   JOURNAL OF CLINICAL INVESTIGATION

Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney

(2015) Rik Westland et al.   KIDNEY INTERNATIONAL

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

(2015) Ryuji Morizane et al.   NATURE BIOTECHNOLOGY

Genetic dissection of kidney disorders

(2015) Friedhelm Hildebrandt   Nature Reviews Nephrology

Genetic, environmental and epigenetic factors involved in CAKUT

(2015) Nayia Nicolaou et al.   Nature Reviews Nephrology

Congenital anomalies of the kidney and urinary tract genetics in mice and men

(2015) Georgina Caruana et al.   NEPHROLOGY

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

(2015) Benjamin S. Freedman et al.   Nature Communications

Genome-wide Association Study and Meta-Analysis Identify ISL1 as Genome-wide Significant Susceptibility Gene for Bladder Exstrophy

(2015) Markus Draaken et al.   PLoS Genetics

OrganIn VitroCulture: What Have We Learned about Early Kidney Development?

(2015) Aleksandra Rak-Raszewska et al.   Stem Cells International

Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome

(2014) Anna Lindstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Enhancer Polymorphism at the Cardiomyocyte Intercalated Disc Protein NOS1AP Locus Is a Major Regulator of the QT Interval

(2014) Ashish Kapoor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Integrin Alpha 8 Recessive Mutations Are Responsible for Bilateral Renal Agenesis in Humans

(2014) Camille Humbert et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic and Epigenomic Analyses of Monozygotic Twins Discordant for Congenital Renal Agenesis

(2014) Meiling Jin et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Interpreting human genetic variation with in vivo zebrafish assays

(2014) Erica E. Davis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Congenital anomalies of the kidney and urinary tract: An embryogenetic review

(2014) Augusto Cesar Soares dos Santos Junior et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Exploring the function of genetic variants in the non-coding genomic regions: approaches for identifying human regulatory variants affecting gene expression

(2014) M. J. Li et al.   BRIEFINGS IN BIOINFORMATICS

Congenital Anomalies of the Kidney and the Urinary Tract (CAKUT)

(2014) Maria M. Rodriguez   Fetal and Pediatric Pathology

Missing heritability of common diseases and treatments outside the protein-coding exome

(2014) Wolfgang Sadee et al.   HUMAN GENETICS

Recessive mutations in CAKUT and VACTERL association

(2014) Rik Westland et al.   KIDNEY INTERNATIONAL

Rare inherited kidney diseases: challenges, opportunities, and perspectives

(2014) Olivier Devuyst et al.   LANCET

Genome-wide association analyses identify variants in developmental genes associated with hypospadias

(2014) Frank Geller et al.   NATURE GENETICS

Copy-number variation associated with congenital anomalies of the kidney and urinary tract

(2014) Georgina Caruana et al.   PEDIATRIC NEPHROLOGY

Ambulatory blood pressure monitoring is recommended in the clinical management of children with a solitary functioning kidney

(2014) Rik Westland et al.   PEDIATRIC NEPHROLOGY

Single-gene causes of congenital anomalies of the kidney and urinary tract (CAKUT) in humans

(2014) Asaf Vivante et al.   PEDIATRIC NEPHROLOGY

RNAi-Mediated Gene silencing in Zebrafish Triggered by Convergent Transcription

(2014) Omozusi E. Andrews et al.   Scientific Reports

Epigenetics of discordant monozygotic twins: implications for disease

(2014) Juan E Castillo-Fernandez et al.   Genome Medicine

Severe Prenatal Renal Anomalies Associated with Mutations in HNF1B or PAX2 Genes

(2013) L. Madariaga et al.   Clinical Journal of the American Society of Nephrology

Clinical Implications of the Solitary Functioning Kidney

(2013) R. Westland et al.   Clinical Journal of the American Society of Nephrology

Precision of Estimating Equations for GFR in Children with a Solitary Functioning Kidney: The KIMONO Study

(2013) R. Westland et al.   Clinical Journal of the American Society of Nephrology

Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association

(2013) Pawaree Saisawat et al.   KIDNEY INTERNATIONAL

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

(2013) Matteo Trudu et al.   NATURE MEDICINE

Unilateral renal agenesis: a systematic review on associated anomalies and renal injury

(2013) Rik Westland et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Mutations in DSTYK and Dominant Urinary Tract Malformations

(2013) S. Sanna-Cherchi et al.   NEW ENGLAND JOURNAL OF MEDICINE

The emerging role of genomics in the diagnosis and workup of congenital urinary tract defects: a novel deletion syndrome on chromosome 3q13.31-22.1

(2013) Anna Materna-Kiryluk et al.   PEDIATRIC NEPHROLOGY

Renin–angiotensin system in ureteric bud branching morphogenesis: implications for kidney disease

(2013) Ihor V. Yosypiv   PEDIATRIC NEPHROLOGY

Gender differences in solitary functioning kidney: do they affect renal outcome?

(2013) Rik Westland et al.   PEDIATRIC NEPHROLOGY

High frequency of kidney and urinary tract anomalies in asymptomatic first-degree relatives of patients with CAKUT

(2013) Burcu Bulum et al.   PEDIATRIC NEPHROLOGY

Risk Factors for Renal Injury in Children With a Solitary Functioning Kidney

(2013) R. Westland et al.   PEDIATRICS

U.S. Centers for Disease Control and Prevention launches new chronic kidney disease surveillance system website

(2013) Tanya Johns et al.   BMC Nephrology

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

(2013) Shin-Ichi Mae et al.   Nature Communications

A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

(2013) J. M. Darlow et al.   Molecular Genetics & Genomic Medicine

Copy-Number Disorders Are a Common Cause of Congenital Kidney Malformations

(2012) Simone Sanna-Cherchi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel genetic aspects of congenital anomalies of kidney and urinary tract

(2012) Stefanie Weber   CURRENT OPINION IN PEDIATRICS

Incidence of renal failure and nephroprotection by RAAS inhibition in heterozygous carriers of X-chromosomal and autosomal recessive Alport mutations

(2012) Johanna Temme et al.   KIDNEY INTERNATIONAL

Interpreting noncoding genetic variation in complex traits and human disease

(2012) Lucas D Ward et al.   NATURE BIOTECHNOLOGY

Genes in the Ureteric Budding Pathway: Association Study on Vesico-Ureteral Reflux Patients

(2012) Albertien M. van Eerde et al.   PLoS One

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

Bladder exstrophy: An epidemiologic study from the International Clearinghouse for Birth Defects Surveillance and Research, and an overview of the literature

(2011) Csaba Siffel et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Company Profile: Complete Genomics Inc.

(2011) Clifford Reid   Future Oncology

Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish

(2011) Krasimir Slanchev et al.   HUMAN MOLECULAR GENETICS

Mutations in Multiple PKD Genes May Explain Early and Severe Polycystic Kidney Disease

(2011) C. Bergmann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The reason why mother nature provided us with two kidneys: the risks of a congenital solitary functioning kidney

(2011) R. Westland et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Renal injury in children with a solitary functioning kidney--the KIMONO study

(2011) R. Westland et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Renin–angiotensin system in ureteric bud branching morphogenesis: insights into the mechanisms

(2011) Ihor V. Yosypiv   PEDIATRIC NEPHROLOGY

Epidemiology of chronic kidney disease in children

(2011) Jérôme Harambat et al.   PEDIATRIC NEPHROLOGY

Mechanisms for Nonrecurrent Genomic Rearrangements Associated with CMT1A or HNPP: Rare CNVs as a Cause for Missing Heritability

(2010) Feng Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Structural variation analysis with strobe reads

(2010) A. Ritz et al.   BIOINFORMATICS

SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation

(2010) X. Nie et al.   DEVELOPMENT

Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice

(2010) Sanjay Jain et al.   JOURNAL OF CLINICAL INVESTIGATION

The burden of kidney disease in Indigenous children of Australia and New Zealand, epidemiology, antecedent factors and progression to chronic kidney disease

(2010) Andrew White et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Gender Differences in Chronic Kidney Disease: Underpinnings and Therapeutic Implications

(2010) Juan Jesús Carrero   KIDNEY & BLOOD PRESSURE RESEARCH

Genetic kidney diseases

(2010) Friedhelm Hildebrandt   LANCET

Genetics of congenital anomalies of the kidney and urinary tract

(2010) Renfang Song et al.   PEDIATRIC NEPHROLOGY

HNF1B alterations associated with congenital anomalies of the kidney and urinary tract

(2010) Makiko Nakayama et al.   PEDIATRIC NEPHROLOGY

Diversity of Human Copy Number Variation and Multicopy Genes

(2010) Peter H. Sudmant et al.   SCIENCE

ADME pharmacogenetics: current practices and future outlook

(2009) Iris Grossman   Expert Opinion on Drug Metabolism & Toxicology

A Recessive Gene for Primary Vesicoureteral Reflux Maps to Chromosome 12p11-q13

(2009) P. L. Weng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal outcome in patients with congenital anomalies of the kidney and urinary tract

(2009) Simone Sanna-Cherchi et al.   KIDNEY INTERNATIONAL

Personalized copy number and segmental duplication maps using next-generation sequencing

(2009) Can Alkan et al.   NATURE GENETICS

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development

(2008) S. Weber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Gender differences in chronic kidney disease

(2008) Kunitoshi Iseki   KIDNEY INTERNATIONAL