Zebrafish as a model for kidney function and disease

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction

(2017) Mohamed A. Elmonem et al.   Scientific Reports

From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?

(2016) Opeyemi Olabisi et al.   CLINICAL NEPHROLOGY

SOS2andACP1Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

(2016) Man Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

c-myb hyperactivity leads to myeloid and lymphoid malignancies in zebrafish

(2016) W Liu et al.   LEUKEMIA

MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury

(2016) Dana Thomasova et al.   Cell Death & Disease

FAT1 mutations cause a glomerulotubular nephropathy

(2016) Heon Yung Gee et al.   Nature Communications

ELMO1 protects renal structure and ultrafiltration in kidney development and under diabetic conditions

(2016) Krishna Rakesh Sharma et al.   Scientific Reports

Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin

(2016) Ahmed M. Kotb et al.   PLoS One

Morpholinos: Antisense and Sensibility

(2015) Martin Blum et al.   DEVELOPMENTAL CELL

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

(2015) Fatma O. Kok et al.   DEVELOPMENTAL CELL

A fresh look at zebrafish from the perspective of cancer research

(2015) Shuai Zhao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Genetic compensation induced by deleterious mutations but not gene knockdowns

(2015) Andrea Rossi et al.   NATURE

Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology

(2015) Barbara Solchenberger et al.   PLoS One

The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule

(2015) Francesca Oltrabella et al.   PLoS Genetics

Recurrent CNVs and SNVs at the NPHP1 Locus Contribute Pathogenic Alleles to Bardet-Biedl Syndrome

(2014) Anna Lindstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9

(2014) Rajat M. Gupta et al.   JOURNAL OF CLINICAL INVESTIGATION

CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity

(2014) Rodolphe Barrangou et al.   MOLECULAR CELL

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

(2014) Shengdar Q Tsai et al.   NATURE BIOTECHNOLOGY

Using next-generation sequencing to isolate mutant genes from forward genetic screens

(2014) Korbinian Schneeberger   NATURE REVIEWS GENETICS

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

(2014) Tessa G. Montague et al.   NUCLEIC ACIDS RESEARCH

Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome

(2013) F. Mahmood et al.   Disease Models & Mechanisms

Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair

(2013) T. O. Auer et al.   GENOME RESEARCH

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease

(2013) Afshin Parsa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

crRNA and tracrRNA guide Cas9-mediated DNA interference inStreptococcus thermophilus

(2013) Tautvydas Karvelis et al.   RNA Biology

New tides: using zebrafish to study renal regeneration

(2013) Kristen K. McCampbell et al.   Translational Research

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

The CRISPR System—Keeping Zebrafish Gene Targeting Fresh

(2013) Patrick R. Blackburn et al.   Zebrafish

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage

(2012) Katherine R. Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Lowe syndrome protein OCRL1 is involved in primary cilia assembly

(2012) Brian G. Coon et al.   HUMAN MOLECULAR GENETICS

Inducible Podocyte Injury and Proteinuria in Transgenic Zebrafish

(2012) W. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TALENs: a widely applicable technology for targeted genome editing

(2012) J. Keith Joung et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kidney organogenesis in the zebrafish: insights into vertebrate nephrogenesis and regeneration

(2012) Gary F. Gerlach et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Lessons from morpholino-based screening in zebrafish

(2011) V. M. Bedell et al.   Briefings in Functional Genomics

Forward and Reverse Genetic Approaches for the Analysis of Vertebrate Development in the Zebrafish

(2011) Nathan D. Lawson et al.   DEVELOPMENTAL CELL

Zebrafish nephrogenesis involves dynamic spatiotemporal expression changes in renal progenitors and essential signals from retinoic acid and irx3b

(2011) Rebecca A. Wingert et al.   DEVELOPMENTAL DYNAMICS

A meckelin–filamin A interaction mediates ciliogenesis

(2011) Matthew Adams et al.   HUMAN MOLECULAR GENETICS

Impaired neural development in a zebrafish model for Lowe syndrome

(2011) Irene Barinaga-Rementeria Ramirez et al.   HUMAN MOLECULAR GENETICS

Identification of adult nephron progenitors capable of kidney regeneration in zebrafish

(2011) Cuong Q. Diep et al.   NATURE

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5

(2010) Yung-Hao Ching et al.   BMC GENETICS

In-vivo characterization of human dilated cardiomyopathy genes in zebrafish

(2009) Britta Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GSK3: a multifaceted kinase in Wnt signaling

(2009) Dianqing Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Primer for Morpholino Use in Zebrafish

(2009) Brent R. Bill et al.   Zebrafish

Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

(2008) Richard Mark White et al.   Cell Stem Cell

Controlling morpholino experiments: don't stop making antisense

(2008) J. S. Eisen et al.   DEVELOPMENT

The zebrafish stress axis: Molecular fallout from the teleost-specific genome duplication event

(2008) Derek Alsop et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Nephrin Mutations Can Cause Childhood-Onset Steroid-Resistant Nephrotic Syndrome

(2008) A. Philippe et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Restoration of renal function in zebrafish models of ciliopathies

(2008) Jonathan L. Tobin et al.   PEDIATRIC NEPHROLOGY