A new genome scan for primary nonsyndromic vesicoureteric reflux emphasizes high genetic heterogeneity and shows linkage and association with various genes already implicated in urinary tract development

TNXB Mutations Can Cause Vesicoureteral Reflux

(2013) R. A. Gbadegesin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Heterozygous non-synonymous ROBO2 variants are unlikely to be sufficient to cause familial vesicoureteric reflux

(2013) Mark G. Dobson et al.   KIDNEY INTERNATIONAL

Copy-Number Disorders Are a Common Cause of Congenital Kidney Malformations

(2012) Simone Sanna-Cherchi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Slit–Roundabout Signaling Regulates the Development of the Cardiac Systemic Venous Return and Pericardium

(2012) Mathilda T.M. Mommersteeg et al.   CIRCULATION RESEARCH

Robo2-Slit and Dcc-Netrin1 Coordinate Neuron Axonal Pathfinding within the Embryonic Axon Tracts

(2012) C. Zhang et al.   JOURNAL OF NEUROSCIENCE

Familial Vesicoureteral Reflux and Reflux Related Morbidity in Relatives of Index Patients with High Grade Vesicoureteral Reflux

(2012) Manuela Hunziker et al.   JOURNAL OF UROLOGY

ENCODE: The human encyclopaedia

(2012) Brendan Maher   NATURE

Genes in the Ureteric Budding Pathway: Association Study on Vesico-Ureteral Reflux Patients

(2012) Albertien M. van Eerde et al.   PLoS One

Genome gender diversity in affected sib-pairs with familial vesico-ureteric reflux identified by single nucleotide polymorphism linkage analysis

(2011) Giovanni S. Marchini et al.   BJU INTERNATIONAL

The GUDMAP database - an online resource for genitourinary research

(2011) S. D. Harding et al.   DEVELOPMENT

Hereditary medullary thyroid carcinoma: the management dilemma

(2011) Ping Zhou et al.   Familial Cancer

A complex regulatory network of transcription factors critical for ocular development and disease

(2011) Moulinath Acharya et al.   HUMAN MOLECULAR GENETICS

SOX9 controls epithelial branching by activating RET effector genes during kidney development

(2011) Antoine Reginensi et al.   HUMAN MOLECULAR GENETICS

Update of PAX2 mutations in renal coloboma syndrome and establishment of a locus-specific database

(2011) Matthew Bower et al.   HUMAN MUTATION

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

(2011) Jason D. Berndt et al.   JOURNAL OF CELL BIOLOGY

Diagnosis, management, and prognosis of HNF1B nephropathy in adulthood

(2011) Stanislas Faguer et al.   KIDNEY INTERNATIONAL

Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis

(2011) Pawaree Saisawat et al.   KIDNEY INTERNATIONAL

Eye development genes and known syndromes

(2011) Anne M. Slavotinek   MOLECULAR GENETICS AND METABOLISM

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

Genetics of vesicoureteral reflux

(2011) Prem Puri et al.   Nature Reviews Urology

Nephron progenitors in the metanephric mesenchyme

(2011) Ryuichi Nishinakamura et al.   PEDIATRIC NEPHROLOGY

Defining the genetic blueprint of kidney development

(2011) S. Steven Potter et al.   PEDIATRIC NEPHROLOGY

Vesicoureteral Reflux and Other Urinary Tract Malformations in Mice Compound Heterozygous for Pax2 and Emx2

(2011) Sami K. Boualia et al.   PLoS One

Defining the Molecular Character of the Developing and Adult Kidney Podocyte

(2011) Eric W. Brunskill et al.   PLoS One

Genetic interactions and modifier genes in Hirschsprung's disease

(2011) Adam S Wallace   WORLD JOURNAL OF GASTROENTEROLOGY

High Expression of Pitx-2 in the ICAT-deficient Metanephros Leads to Developmental Arrest

(2010) Yoshimi Hasegawa et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

ROADTRIPS: Case-Control Association Testing with Partially or Completely Unknown Population and Pedigree Structure

(2010) Timothy Thornton et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Isoform- and dose-sensitive feedback interactions between paired box 6 gene and δ-catenin in cell differentiation and death

(2010) Jiao Zhang et al.   EXPERIMENTAL CELL RESEARCH

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart

(2010) Sandra Puskaric et al.   HUMAN MOLECULAR GENETICS

Mutations in SOX17 are associated with congenital anomalies of the kidney and the urinary tract

(2010) Stefania Gimelli et al.   HUMAN MUTATION

High Incidence of Vesicoureteral Reflux in Mice With Fgfr2 Deletion in Kidney Mesenchyma

(2010) David S. Hains et al.   JOURNAL OF UROLOGY

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Mapping candidate regions and genes for congenital anomalies of the kidneys and urinary tract (CAKUT) by array-based comparative genomic hybridization

(2010) Stefanie Weber et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Genetics of congenital anomalies of the kidney and urinary tract

(2010) Renfang Song et al.   PEDIATRIC NEPHROLOGY

GDNF/Ret signaling and renal branching morphogenesis

(2010) Frank Costantini   Organogenesis

Gene Conversion between the X Chromosome and the Male-Specific Region of the Y Chromosome at a Translocation Hotspot

(2009) Zoë H. Rosser et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Plumbing in the embryo: developmental defects of the urinary tracts

(2009) N Uetani et al.   CLINICAL GENETICS

Kidney development: from ureteric bud formation to branching morphogenesis

(2009) Odyssé Michos   CURRENT OPINION IN GENETICS & DEVELOPMENT

A genome scan in affected sib-pairs with familial vesicoureteral reflux identifies a locus on chromosome 5

(2009) Christine E Briggs et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The increased incidence of the RET p.Gly691Ser variant in French-Canadian vesicoureteric reflux patients is not replicated by a larger study in Ireland

(2009) John M. Darlow et al.   HUMAN MUTATION

Whole-Genome Linkage and Association Scan in Primary, Nonsyndromic Vesicoureteric Reflux

(2009) H. J. Cordell et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Recessive Gene for Primary Vesicoureteral Reflux Maps to Chromosome 12p11-q13

(2009) P. L. Weng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Familial Vesicoureteral Reflux—Is Screening Beneficial?

(2009) Maria Menezes et al.   JOURNAL OF UROLOGY

Mapping of a new locus for congenital anomalies of the kidney and urinary tract on chromosome 8q24

(2009) S. Ashraf et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

dup(19)(q12q13.2): Array-based Genotype–Phenotype Correlation of a New Possibly Obesity-related Syndrome

(2009) Josef Davidsson et al.   Obesity

Five cases of severe vesico-ureteric reflux in a family with an X-linked compatible trait

(2009) Mitra Naseri et al.   PEDIATRIC NEPHROLOGY

Likelihood-Based Association Analysis for Nuclear Families and Unrelated Subjects with Missing Genotype Data

(2008) Frank Dudbridge   HUMAN HEREDITY

RET Gly691Ser mutation is associated with primary vesicoureteral reflux in the French-Canadian population from Quebec

(2008) Yaoming Yang et al.   HUMAN MUTATION

Vesicoureteral Reflux

(2008) G. Williams et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

ROBO2 Gene Variants Are Associated with Familial Vesicoureteral Reflux

(2008) A. M. Bertoli-Avella et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SIX2 and BMP4 Mutations Associate With Anomalous Kidney Development

(2008) S. Weber et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

GUDMAP: The Genitourinary Developmental Molecular Anatomy Project

(2008) A. P. McMahon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genetic and developmental basis for urinary tract obstruction

(2008) Feng Chen   PEDIATRIC NEPHROLOGY

A genome search for primary vesicoureteral reflux shows further evidence for genetic heterogeneity

(2008) Maria Luisa Conte et al.   PEDIATRIC NEPHROLOGY