Photodynamic-based combinatorial cancer therapy strategies: Tuning the properties of nanoplatform according to oncotherapy needs

Recent Progress in Boosted PDT Induced Immunogenic Cell Death for Tumor Immunotherapy

(2021) Jun Li et al.   CHEMICAL RESEARCH IN CHINESE UNIVERSITIES

Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy

(2021) Shibo Lv et al.   MOLECULAR PHARMACEUTICS

Biophysical and Biological Features of Third Generation Photosensitizers Used in Anticancer Photodynamic Therapy: Review

(2021) Ivan S. Mfouo-Tynga et al.   Photodiagnosis and Photodynamic Therapy

Site-Specific Dual-Labeling of a VHH with a Chelator and a Photosensitizer for Nuclear Imaging and Targeted Photodynamic Therapy of EGFR-Positive Tumors

(2021) Emma Renard et al.   Cancers

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Attritional evaluation of lipophilic and hydrophilic metallated phthalocyanines for oncological photodynamic therapy

(2021) Lionel Mendes Dias et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Red-Light-Responsive Ru Complex Photosensitizer for Lysosome Localization Photodynamic Therapy

(2021) Guangli He et al.   ACS Applied Materials & Interfaces

Biomimetic Nanotheranostics Camouflaged with Cancer Cell Membranes Integrating Persistent Oxygen Supply and Homotypic Targeting for Hypoxic Tumor Elimination

(2021) Hongliang Chen et al.   ACS Applied Materials & Interfaces

Controlled aggregation of methylene blue in silica–methylene blue nanocomposite for enhanced 1O2 generation

(2021) Satoshi Saita et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Carbon quantum dots/Bi4O5Br2 photocatalyst with enhanced photodynamic therapy: killing of lung cancer (A549) cells in vitro

(2021) Bing He et al.   RARE METALS

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

(2021) Chi Zhang et al.   Nature Communications

Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy

(2021) Zonglang Zhou et al.   ACS Omega

Ruthenium(II) complexes coordinated to graphitic carbon nitride: Oxygen self-sufficient photosensitizers which produce multiple ROS for photodynamic therapy in hypoxia

(2021) Fangmian Wei et al.   BIOMATERIALS

Plasma membrane targeted photodynamic O2 economizer for hypoxic tumor therapy

(2021) Gui-Ling Fan et al.   BIOMATERIALS

Photodynamic creation of artificial tumor microenvironments to collectively facilitate hypoxia-activated chemotherapy delivered by coagulation-targeting liposomes

(2021) Chunjie Wang et al.   CHEMICAL ENGINEERING JOURNAL

Anticancer Activity, DNA Binding, and Photodynamic Properties of a N∧C∧N-Coordinated Pt(II) Complex

(2021) Stefano Scoditti et al.   INORGANIC CHEMISTRY

Coordination Complexes as a New Generation Photosensitizer for Photodynamic Anticancer Therapy

(2021) Kacper Pobłocki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanostructured Phthalocyanine Assemblies with Efficient Synergistic Effect of Type I Photoreaction and Photothermal Action to Overcome Tumor Hypoxia in Photodynamic Therapy

(2021) Yuan-Yuan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bright Bacterium for Hypoxia‐Tolerant Photodynamic Therapy Against Orthotopic Colon Tumors by an Interventional Method

(2021) Daoming Zhu et al.   Advanced Science

A carrier-free metal-coordinated dual-photosensitizers nanotheranostic with glutathione-depletion for fluorescence/photoacoustic imaging-guided tumor phototherapy

(2021) Luping Chen et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Mn(II)-directed dual-photosensitizers co-assemblies for multimodal imaging-guided self-enhanced phototherapy

(2021) Jinxue Liu et al.   Materials Science & Engineering C-Materials for Biological Applications

Isocyanide Substitution in Acridine Orange Shifts DNA Damage-Mediated Phototoxicity to Permeabilization of the Lysosomal Membrane in Cancer Cells

(2021) Csaba Bankó et al.   Cancers

Self-Delivered and Self-Monitored Chemo-Photodynamic Nanoparticles with Light-Triggered Synergistic Antitumor Therapies by Downregulation of HIF-1α and Depletion of GSH

(2020) Zhongtao Zhang et al.   ACS Applied Materials & Interfaces

Conjugation of a Scintillator Complex and Gold Nanorods for Dual-Modal Image-Guided Photothermal and X-Ray-Induced Photodynamic Therapy of Tumors

(2020) Li Luo et al.   ACS Applied Materials & Interfaces

Environmentally Friendly Synthesis of Au–Te-Clustered Nanoworms via Galvanic Replacement for Wavelength-Selective Combination Cancer Therapy

(2020) Seounghun Kang et al.   ACS Applied Materials & Interfaces

Sequential-targeting nanocarriers with pH-controlled charge reversal for enhanced mitochondria-located photodynamic-immunotherapy of cancer

(2020) Na Peng et al.   Acta Biomaterialia

Engineering of Upconverted Metal–Organic Frameworks for Near-Infrared Light-Triggered Combinational Photodynamic/Chemo-/Immunotherapy against Hypoxic Tumors

(2020) Yulei Shao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy

(2020) Hongzhang Deng et al.   NANO LETTERS

PCN-Fe(III)-PTX nanoparticles for MRI guided high efficiency chemo-photodynamic therapy in pancreatic cancer through alleviating tumor hypoxia

(2020) Tao Zhang et al.   Nano Research

Light Sources and Dosimetry Techniques for Photodynamic Therapy

(2020) Michele M. Kim et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Immune Responses after Vascular Photodynamic Therapy with Redaporfin

(2020) Ana Catarina S. Lobo et al.   Journal of Clinical Medicine

Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma

(2020) Natalia Trempolec et al.   Cancers

Oxygen Self-Sufficient Core–Shell Metal–Organic Framework-Based Smart Nanoplatform for Enhanced Synergistic Chemotherapy and Photodynamic Therapy

(2020) Shen-Zhen Ren et al.   ACS Applied Materials & Interfaces

Persistent Luminescence Nanoplatform with Fenton-like Catalytic Activity for Tumor Multimodal Imaging and Photoenhanced Combination Therapy

(2020) Shuqi Wu et al.   ACS Applied Materials & Interfaces

Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy

(2020) Jing Gao et al.   ACTA PHARMACOLOGICA SINICA

X‐Ray‐Induced Persistent Luminescence Promotes Ultrasensitive Imaging and Effective Inhibition of Orthotopic Hepatic Tumors

(2020) Tianhang Shi et al.   ADVANCED FUNCTIONAL MATERIALS

Gadolinium–Rose Bengal Coordination Polymer Nanodots for MR‐/Fluorescence‐Image‐Guided Radiation and Photodynamic Therapy

(2020) Wenjing Sun et al.   ADVANCED MATERIALS

Semiconducting Polycomplex Nanoparticles for Photothermal Ferrotherapy of Cancer

(2020) Shasha He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sulphur doped carbon dots enhance photodynamic therapy via PI3K/Akt signalling pathway

(2020) Yanjing Li et al.   CELL PROLIFERATION

Homologous-targeting biomimetic nanoparticles for photothermal therapy and Nrf2-siRNA amplified photodynamic therapy against oral tongue squamous cell carcinoma

(2020) Shurui Shi et al.   CHEMICAL ENGINEERING JOURNAL

Enhanced Upconversion Luminescence-Guided Synergistic Antitumor Therapy Based on Photodynamic Therapy and Immune Checkpoint Blockade

(2020) Bi Lin et al.   CHEMISTRY OF MATERIALS

All-in-One Molecular Aggregation-Induced Emission Theranostics: Fluorescence Image Guided and Mitochondria Targeted Chemo- and Photodynamic Cancer Cell Ablation

(2020) Bing Guo et al.   CHEMISTRY OF MATERIALS

Multidentate Phenanthroline Ligands Containing Additional Donor Moieties and Their Resulting Cu(I) and Ru(II) Photosensitizers: A Comparative Study

(2020) Martin Rentschler et al.   INORGANIC CHEMISTRY

Tumor-targeting and imaging micelles for pH-triggered anticancer drug release and combined photodynamic therapy

(2020) Qianqian Qi et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

A Highly‐Efficient Type I Photosensitizer with Robust Vascular‐Disruption Activity for Hypoxic‐and‐Metastatic Tumor Specific Photodynamic Therapy

(2020) Dapeng Chen et al.   Small

Application of Mitochondrially Targeted Nanoconstructs to Neoadjuvant X-ray-Induced Photodynamic Therapy for Rectal Cancer

(2020) Wei Deng et al.   ACS Central Science

NIR-Triggered Sequentially Responsive Nanocarriers Amplified Cascade Synergistic Effect of Chemo-Photodynamic Therapy with Inspired Antitumor Immunity

(2020) Feiyang Jin et al.   ACS Applied Materials & Interfaces

All-in-One Theranostic Nanomedicine with Ultrabright Second Near-Infrared Emission for Tumor-Modulated Bioimaging and Chemodynamic/Photodynamic Therapy

(2020) Jiating Xu et al.   ACS Nano

Oxygen-producing catalase-based prodrug nanoparticles overcoming resistance in hypoxia-mediated chemo-photodynamic therapy

(2020) Xu Cheng et al.   Acta Biomaterialia

Molecular Engineering to Boost AIE-Active Free Radical Photogenerators and Enable High-Performance Photodynamic Therapy under Hypoxia

(2020) Qing Wan et al.   ADVANCED FUNCTIONAL MATERIALS

Aggregation‐Induced Emission Luminogens Married to 2D Black Phosphorus Nanosheets for Highly Efficient Multimodal Theranostics

(2020) Jiachang Huang et al.   ADVANCED MATERIALS

Electromagnetic nanomedicines for combinational cancer immunotherapy

(2020) Kanyi Pu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibiting tumor oxygen metabolism and simultaneously generating oxygen by intelligent upconversion nanotherapeutics for enhanced photodynamic therapy

(2020) Dan Wang et al.   BIOMATERIALS

Stepwise-activatable hypoxia triggered nanocarrier-based photodynamic therapy for effective synergistic bioreductive chemotherapy

(2020) Khan Malik Ihsanullah et al.   BIOMATERIALS

Dendritic cell vaccine for the effective immunotherapy of breast cancer

(2020) Jiang Ni et al.   BIOMEDICINE & PHARMACOTHERAPY

Co-delivery of hydrophilic/hydrophobic drugs by multifunctional yolk-shell nanoparticles for hepatocellular carcinoma theranostics

(2020) Xiangjun Chen et al.   CHEMICAL ENGINEERING JOURNAL

Tumor-targeted upconverting nanoplatform constructed by host-guest interaction for near-infrared-light-actuated synergistic photodynamic-/chemotherapy

(2020) Xuemei Yao et al.   CHEMICAL ENGINEERING JOURNAL

Construction of microneedle-assisted co-delivery platform and its combining photodynamic/immunotherapy

(2020) Shi-Xiong Chen et al.   JOURNAL OF CONTROLLED RELEASE

Sequential PDT and PTT Using Dual‐Modal Single‐Walled Carbon Nanohorns Synergistically Promote Systemic Immune Responses against Tumor Metastasis and Relapse

(2020) Jingxing Yang et al.   Advanced Science

Engineering autologous tumor cell vaccine to locally mobilize antitumor immunity in tumor surgical bed

(2020) Lei Fang et al.   Science Advances

ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease

(2020) Dominic S. A. Simpson et al.   Antioxidants

Self-Assembled Hybrid Nanocomposites for Multimodal Imaging-Guided Photothermal Therapy of Lymph Node Metastasis

(2020) Wu Cai et al.   ACS Applied Materials & Interfaces

Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors

(2020) Kuo-Ching Mei et al.   ACS Nano

An NIR‐II‐Emissive Photosensitizer for Hypoxia‐Tolerant Photodynamic Theranostics

(2020) Lanqing Li et al.   ADVANCED MATERIALS

Cascade of reactive oxygen species generation by polyprodrug for combinational photodynamic therapy

(2020) Zujian Feng et al.   BIOMATERIALS

Fucoidan-based, tumor-activated nanoplatform for overcoming hypoxia and enhancing photodynamic therapy and antitumor immunity

(2020) Chu-Hung Chung et al.   BIOMATERIALS

Enhancing Förster Resonance Energy Transfer (FRET) Efficiency of Titania–Lanthanide Hybrid Upconversion Nanomaterials by Shortening the Donor–Acceptor Distance

(2020) Syue-Liang Lin et al.   Nanomaterials

Polymeric Nanoparticles with ROS‐Responsive Prodrug and Platinum Nanozyme for Enhanced Chemophotodynamic Therapy of Colon Cancer

(2020) Ying Hao et al.   Advanced Science

Functionalized g-C3N4 nanosheets for potential use in magnetic resonance imaging-guided sonodynamic and nitric oxide combination therapy

(2020) Yan Zheng et al.   Acta Biomaterialia

Activatable Polymer Nanoenzymes for Photodynamic Immunometabolic Cancer Therapy

(2020) Ziling Zeng et al.   ADVANCED MATERIALS

Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy

(2020) Yuanyuan Yang et al.   BIOMATERIALS

Construction of thiol-capped ultrasmall Au–Bi bimetallic nanoparticles for X-ray CT imaging and enhanced antitumor therapy efficiency

(2020) Fei He et al.   BIOMATERIALS

A glutathione-activatable nanoplatform for enhanced photodynamic therapy with simultaneous hypoxia relief and glutathione depletion

(2020) Furong Liu et al.   CHEMICAL ENGINEERING JOURNAL

Fluorine assembly nanocluster breaks the shackles of immunosuppression to turn the cold tumor hot

(2020) Zhaoting Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosome-based photoacoustic imaging guided photodynamic and immunotherapy for the treatment of pancreatic cancer

(2020) Yongho Jang et al.   JOURNAL OF CONTROLLED RELEASE

Molecular engineering to accelerate cancer cell discrimination and boost AIE-active type I photosensitizer for photodynamic therapy under hypoxia

(2020) Xinxin Zhao et al.   CHEMICAL ENGINEERING JOURNAL

NIR-Triggered Phototherapy and Immunotherapy via an Antigen-Capturing Nanoplatform for Metastatic Cancer Treatment

(2019) Meng Wang et al.   Advanced Science

Gaseous signaling molecules and their application in resistant cancer treatment: from invisible to visible

(2019) Qingbin Cui et al.   Future Medicinal Chemistry

In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy

(2019) Weijing Yang et al.   ACS Nano

Rodlike MSN@Au Nanohybrid-Modified Supermolecular Photosensitizer for NIRF/MSOT/CT/MR Quadmodal Imaging-Guided Photothermal/Photodynamic Cancer Therapy

(2019) Shan Yang et al.   ACS Applied Materials & Interfaces

Hyaluronidase with pH‐responsive Dextran Modification as an Adjuvant Nanomedicine for Enhanced Photodynamic‐Immunotherapy of Cancer

(2019) Hairong Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Specifically Generation of Singlet Oxygen via Russell Mechanism in Hypoxic Tumor and GSH Depletion by Cu-TCPP Nanosheets for Cancer Therapy

(2019) Chao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The effect of reactive oxygen species (ROS) and ROS-scavenging enzymes, superoxide dismutase and catalase, on the thermotolerant ability of Corynebacterium glutamicum

(2019) Nawarat Nantapong et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Low dose photodynamic therapy harmonizes with radiation therapy to induce beneficial effects on pancreatic heterocellular spheroids

(2019) Anne-Laure Bulin et al.   Oncotarget

Fenton reaction assisted photodynamic therapy for cancer with multifunctional magnetic nanoparticles

(2019) Huabo Hou et al.   ACS Applied Materials & Interfaces

Organic Semiconducting Pro-nanostimulants for Near-Infrared Photoactivatable Cancer Immunotherapy

(2019) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoactivated Lysosomal Escape of a Monofunctional PtII Complex Pt-BDPA for Nucleus Access

(2019) Xuling Xue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

H2O2-responsive biodegradable nanomedicine for cancer-selective dual-modal imaging guided precise photodynamic therapy

(2019) Qin Zeng et al.   BIOMATERIALS

X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors

(2019) Samana Shrestha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

“Three-Bullets” Loaded Mesoporous Silica Nanoparticles for Combined Photo/Chemotherapy

(2019) André Luiz Tessaro et al.   Nanomaterials

Improved Red Emission and Short-Wavelength Infrared Luminescence under 808 nm Laser for Tumor Theranostics

(2019) Ruichan Lv et al.   ACS Biomaterials-Science & Engineering

Artificial Cell-Mediated Photodynamic Therapy Enhanced Anticancer Efficacy through Combination of Tumor Disruption and Immune Response Stimulation

(2019) Jiang Ni et al.   ACS Omega

Near-Infrared Excited Orthogonal Emissive Upconversion Nanoparticles for Imaging-Guided On-Demand Therapy

(2019) Ming Tang et al.   ACS Nano

Gas-Mediated Cancer Bioimaging and Therapy

(2019) Lichan Chen et al.   ACS Nano

Positron Emission Tomography-Guided Photodynamic Therapy with Biodegradable Mesoporous Silica Nanoparticles for Personalized Cancer Immunotherapy

(2019) Cheng Xu et al.   ACS Nano

Near‐Infrared Photoactivatable Semiconducting Polymer Nanoblockaders for Metastasis‐Inhibited Combination Cancer Therapy

(2019) Jingchao Li et al.   ADVANCED MATERIALS

Polymer–Upconverting Nanoparticle Hybrid Micelles for Enhanced Synergistic Chemo–Photodynamic Therapy: Effects of Emission–Absorption Spectral Match

(2019) Yu Chen et al.   BIOMACROMOLECULES

Construction of lanthanide-doped upconversion nanoparticle-Uelx Europaeus Agglutinin-I bioconjugates with brightness red emission for ultrasensitive in vivo imaging of colorectal tumor

(2019) Rongrong Tian et al.   BIOMATERIALS

Type I photodynamic therapy by organic–inorganic hybrid materials: From strategies to applications

(2019) Yu-Ying Wang et al.   COORDINATION CHEMISTRY REVIEWS

Photobiomodulation combined with photodynamic therapy using ruthenium phthalocyanine complexes in A375 melanoma cells: Effects of nitric oxide generation and ATP production

(2019) Laísa Bonafim Negri et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Predictors and Limitations of the Penetration Depth of Photodynamic Effects in the Rodent Brain

(2019) Collin T. Inglut et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

A self-assembled Ru–Pt metallacage as a lysosome-targeting photosensitizer for 2-photon photodynamic therapy

(2019) Zhixuan Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MnO2-DNAzyme-photosensitizer nanocomposite with AIE characteristic for cell imaging and photodynamic-gene therapy

(2019) Xudong Wang et al.   TALANTA

Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti‐Metastatic Immunotherapy

(2019) Zheng Wang et al.   Advanced Science

Low Photosensitizer Dose and Early Radiotherapy Enhance Antitumor Immune Response of Photodynamic Therapy-Based Dendritic Cell Vaccination

(2019) Bastien Doix et al.   Frontiers in Oncology

Multifunctional Theranostic Liposomes Loaded with a Hypoxia-Activated Prodrug for Cascade-Activated Tumor Selective Combination Therapy

(2019) Yeneng Dai et al.   ACS Applied Materials & Interfaces

Enzyme-Driven Membrane-Targeted Chimeric Peptide for Enhanced Tumor Photodynamic Immunotherapy

(2019) Chi Zhang et al.   ACS Nano

NIR/ROS‐Responsive Black Phosphorus QD Vesicles as Immunoadjuvant Carrier for Specific Cancer Photodynamic Immunotherapy

(2019) Zhi Li et al.   ADVANCED FUNCTIONAL MATERIALS

Aggregation-Induced Emission Gold Clustoluminogens for Enhanced Low-Dose X-ray-Induced Photodynamic Therapy

(2019) Wenjing Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tandem activated photodynamic and chemotherapy: Using pH-Sensitive nanosystems to realize different tumour distributions of photosensitizer/prodrug for amplified combination therapy

(2019) Yu Ji et al.   BIOMATERIALS

Drug delivery micelles with efficient near-infrared photosensitizer for combined image-guided photodynamic therapy and chemotherapy of drug-resistant cancer

(2019) Shijie Zhen et al.   BIOMATERIALS

Glutathione depletion and dual-model oxygen balance disruption for photodynamic therapy enhancement

(2019) Weilan Li et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Combination of photodynamic therapy and gene silencing achieved through the hierarchical self-assembly of porphyrin-siRNA complexes

(2019) Nabila Laroui et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Investigation of combined photodynamic and radiotherapy effects of gallium phthalocyanine chloride on MCF-7 breast cancer cells

(2019) Sara Mayahi et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Photodynamic Therapy Combined with Antihypoxic Signaling and CpG Adjuvant as an In Situ Tumor Vaccine Based on Metal–Organic Framework Nanoparticles to Boost Cancer Immunotherapy

(2019) Zhixiong Cai et al.   Advanced Healthcare Materials

Photodynamic Therapy: A Brief History

(2019) David Kessel   Journal of Clinical Medicine

Mitochondria-Targeting Immunogenic Cell Death Inducer Improves the Adoptive T-Cell Therapy Against Solid Tumor

(2019) Qingzhi Jiang et al.   Frontiers in Oncology

Efficient Near-Infrared Photosensitizer with Aggregation-Induced Emission for Imaging-Guided Photodynamic Therapy in Multiple Xenograft Tumor Models

(2019) Jun Dai et al.   ACS Nano

The potentiated checkpoint blockade immunotherapy by ROS-responsive nanocarrier-mediated cascade chemo-photodynamic therapy

(2019) Liqin Hu et al.   BIOMATERIALS

Central metal-derived co-assembly of biomimetic GdTPP/ZnTPP porphyrin nanocomposites for enhanced dual-modal imaging-guided photodynamic therapy

(2019) Jiefei Wang et al.   BIOMATERIALS

Layer structured LDH_ZnPcG4-FA nanoplatform for targeted and imaging guided chemo-photodynamic therapy mediated by 650 nm light

(2019) Zhao Wang et al.   CHEMICAL ENGINEERING JOURNAL

Determination and analysis of singlet oxygen quantum yields of talaporfin sodium, protoporphyrin IX, and lipidated protoporphyrin IX using near-infrared luminescence spectroscopy

(2019) Takahiro Nishimura et al.   LASERS IN MEDICAL SCIENCE

Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer

(2019) Ang Gao et al.   NANO LETTERS

Immunogenic cell death induced by a new photodynamic therapy based on photosens and photodithazine

(2019) Victoria D. Turubanova et al.   Journal for ImmunoTherapy of Cancer

Evaluation of NIR and Raman spectroscopies for the quality analytical control of a solid pharmaceutical formulation with three active ingredients.

(2019) César Pino-Torres et al.   MICROCHEMICAL JOURNAL

meso-Tetrahydroxyphenylchlorin-Conjugated Gold Nanoparticles as a Tool To Improve Photodynamic Therapy

(2018) Elina Haimov et al.   ACS Applied Materials & Interfaces

Artemisinin and AIEgen Conjugate for Mitochondria-Targeted and Image-Guided Chemo- and Photodynamic Cancer Cell Ablation

(2018) Guangxue Feng et al.   ACS Applied Materials & Interfaces

Lanthanide-Doped Core–Shell–Shell Nanocomposite for Dual Photodynamic Therapy and Luminescence Imaging by a Single X-ray Excitation Source

(2018) Chang-Chieh Hsu et al.   ACS Applied Materials & Interfaces

Enhanced Immunotherapy Based on Photodynamic Therapy for Both Primary and Lung Metastasis Tumor Eradication

(2018) Wen Song et al.   ACS Nano

Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration

(2018) Liangliang Dai et al.   ADVANCED FUNCTIONAL MATERIALS

Oxygen-Generating MnO2 Nanodots-Anchored Versatile Nanoplatform for Combined Chemo-Photodynamic Therapy in Hypoxic Cancer

(2018) Wentao Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Enhanced Cellular Ablation by Attenuating Hypoxia Status and Reprogramming Tumor-Associated Macrophages via NIR Light-Responsive Upconversion Nanocrystals

(2018) Xiangzhao Ai et al.   BIOCONJUGATE CHEMISTRY

Cytokine induced killer cells-assisted delivery of chlorin e6 mediated self-assembled gold nanoclusters to tumors for imaging and immuno-photodynamic therapy

(2018) Fangfang Xia et al.   BIOMATERIALS

SnWO 4 -based nanohybrids with full energy transfer for largely enhanced photodynamic therapy and radiotherapy

(2018) Meng Zhang et al.   BIOMATERIALS

Photodynamic therapy – mechanisms, photosensitizers and combinations

(2018) Stanisław Kwiatkowski et al.   BIOMEDICINE & PHARMACOTHERAPY

Photo-based PDT/PTT dual model killing and imaging of cancer cells using phycocyanin-polypyrrole nanoparticles

(2018) Subramaniyan Bharathiraja et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

X-ray radiation-induced and targeted photodynamic therapy with folic acid-conjugated biodegradable nanoconstructs

(2018) Sandhya Clement et al.   International Journal of Nanomedicine

Magnetic-luminescent cerium-doped gadolinium aluminum garnet nanoparticles for simultaneous imaging and photodynamic therapy of cancer cells

(2018) Akhil Jain et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Single 808 nm Laser Treatment Comprising Photothermal and Photodynamic Therapies by Using Gold Nanorods Hybrid Upconversion Particles

(2018) Ming-Hsien Chan et al.   Journal of Physical Chemistry C

Highly Emissive Self-Assembled BODIPY-Platinum Supramolecular Triangles

(2018) Jiong Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoscale Metal–Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy

(2018) Guangxu Lan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Smart Nanoreactors for pH-Responsive Tumor Homing, Mitochondria-Targeting, and Enhanced Photodynamic-Immunotherapy of Cancer

(2018) Guangbao Yang et al.   NANO LETTERS

Resonance Energy Transfer-Promoted Photothermal and Photodynamic Performance of Gold–Copper Sulfide Yolk–Shell Nanoparticles for Chemophototherapy of Cancer

(2018) Yun Chang et al.   NANO LETTERS

Engineering of tungsten carbide nanoparticles forimaging-guided single 1,064 nm laser-activated dual-type photodynamic and photothermal therapy of cancer

(2018) Shi-Hua Li et al.   Nano Research

Heterometallic Ru–Pt metallacycle for two-photon photodynamic therapy

(2018) Zhixuan Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Achieving efficient photodynamic therapy under both normoxia and hypoxia using cyclometalated Ru(ii) photosensitizer through type I photochemical process

(2018) Zhuang Lv et al.   Chemical Science

Targeted Delivery of Functionalized Upconversion Nanoparticles for Externally Triggered Photothermal/Photodynamic Therapies of Brain Glioblastoma

(2018) Yuan-Chung Tsai et al.   Theranostics

Albumin/sulfonamide stabilized iron porphyrin metal organic framework nanocomposites: targeting tumor hypoxia by carbonic anhydrase IX inhibition and T1–T2 dual mode MRI guided photodynamic/photothermal therapy

(2018) Wei Zhu et al.   Journal of Materials Chemistry B

Near infrared light triggered reactive oxygen species responsive nanoparticles for chemo-photodynamic combined therapy

(2018) Xuefei Zhang et al.   Journal of Materials Chemistry B

Role of Mn2+ Doping in the Preparation of Core-Shell Structured Fe3O4@upconversion Nanoparticles and Their Applications in T1/T2-Weighted Magnetic Resonance Imaging, Upconversion Luminescent Imaging and Near-Infrared Activated Photodynamic Therapy

(2018) Yang Luo et al.   Nanomaterials

Gas-Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

(2018) Luodan Yu et al.   ADVANCED MATERIALS

Ultra-high FRET efficiency NaGdF4: Tb3+-Rose Bengal biocompatible nanocomposite for X-ray excited photodynamic therapy application

(2018) Wenli Zhang et al.   BIOMATERIALS

Dihydroartemisinin Increases the Sensitivity of Photodynamic Therapy Via NF-κB/HIF-1α/VEGF Pathway in Esophageal Cancer Cell in vitro and in vivo

(2018) Yanjing Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Enhancing Type I Photochemistry in Photodynamic Therapy Under Near Infrared Light by Using Antennae-Fullerene Complexes

(2018) Qian Li et al.   CYTOMETRY PART A

Quad-Model Imaging-Guided High-Efficiency Phototherapy Based on Upconversion Nanoparticles and ZnFe2O4 Integrated Graphene Oxide

(2018) Huiting Bi et al.   INORGANIC CHEMISTRY

All-inorganic perovskite nanocrystal scintillators

(2018) Qiushui Chen et al.   NATURE

Hypoxia-triggered gene therapy: a new drug delivery system to utilize photodynamic-induced hypoxia for synergistic cancer therapy

(2018) Caixia Huang et al.   Journal of Materials Chemistry B

Large-Pore Mesoporous-Silica-Coated Upconversion Nanoparticles as Multifunctional Immunoadjuvants with Ultrahigh Photosensitizer and Antigen Loading Efficiency for Improved Cancer Photodynamic Immunotherapy

(2018) Binbin Ding et al.   ADVANCED MATERIALS

CT/MRI-Guided Synergistic Radiotherapy and X-ray Inducible Photodynamic Therapy Using Tb-Doped Gd-W-Nanoscintillators

(2018) Xujiang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

O2-Loaded pH-Responsive Multifunctional Nanodrug Carrier for Overcoming Hypoxia and Highly Efficient Chemo-Photodynamic Cancer Therapy

(2018) Zhongxi Xie et al.   CHEMISTRY OF MATERIALS

Increased proliferation/aggressiveness and metastatic potential of therapy targeted surviving breast adenocarcinoma cells as well as bystander non-targeted cancer cells; role of therapy-induced iNOS/NO, and beneficial effects of iNOS inhibitors

(2018) Witold Korytowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nanoparticulate photosensitizer decorated with hyaluronic acid for photodynamic/photothermal cancer targeting therapy

(2018) Xiaoling Wang et al.   Nanomedicine

Carbon Dots @ Platinum Porphyrin Composite as Theranostic Nanoagent for Efficient Photodynamic Cancer Therapy

(2018) Fengshou Wu et al.   Nanoscale Research Letters

New insights into nanomaterials combating bacteria: ROS and beyond

(2018) Zhengwei Liu et al.   Science China-Life Sciences

Combination of CuS and g-C3N4 QDs on upconversion nanoparticles for targeted photothermal and photodynamic cancer therapy

(2018) Mengshu Xu et al.   CHEMICAL ENGINEERING JOURNAL

Autophagy inhibitor enhance ZnPc/BSA nanoparticle induced photodynamic therapy by suppressing PD-L1 expression in osteosarcoma immunotherapy

(2018) Wei Yu et al.   BIOMATERIALS

Inhibition of lymphangiogenesis impairs antitumour effects of photodynamic therapy and checkpoint inhibitors in mice

(2017) Angelika Muchowicz et al.   EUROPEAN JOURNAL OF CANCER

The antitrypanosomal and antitubercular activity of some nitro(triazole/imidazole)-based aromatic amines

(2017) Maria V. Papadopoulou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triple-functional albumin-based nanoparticles for combined chemotherapy and photodynamic therapy of pancreatic cancer with lymphatic metastases

(2017) Xinzhe Yu et al.   International Journal of Nanomedicine

pH-Sensitive PEGylated liposomes for delivery of an acidic dinitrobenzamide mustard prodrug: Pathways of internalization, cellular trafficking and cytotoxicity to cancer cells

(2017) Mimi M. Yang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Drug-induced co-assembly of albumin/catalase as smart nano-theranostics for deep intra-tumoral penetration, hypoxia relieve, and synergistic combination therapy

(2017) Qian Chen et al.   JOURNAL OF CONTROLLED RELEASE

A “win–win” nanoplatform: TiO2:Yb,Ho,F for NIR light-induced synergistic therapy and imaging

(2017) Jie Zhou et al.   Nanoscale

Integration of IR-808 Sensitized Upconversion Nanostructure and MoS2 Nanosheet for 808 nm NIR Light Triggered Phototherapy and Bioimaging

(2017) Jiating Xu et al.   Small

Combination photodynamic therapy of human breast cancer using salicylic acid and methylene blue

(2017) Reza Hosseinzadeh et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Functionality and versatility of aggregation-induced emission luminogens

(2017) Guangxue Feng et al.   Applied Physics Reviews

Photodynamic-Immune Checkpoint Therapy Eradicates Local and Distant Tumors by CD8 + T Cells

(2017) Jan Willem Kleinovink et al.   Cancer Immunology Research

LiGa5O8:Cr-based theranostic nanoparticles for imaging-guided X-ray induced photodynamic therapy of deep-seated tumors

(2017) Hongmin Chen et al.   Materials Horizons

Synthesis and Optimization of MoS2 @Fe3 O4 -ICG/Pt(IV) Nanoflowers for MR/IR/PA Bioimaging and Combined PTT/PDT/Chemotherapy Triggered by 808 nm Laser

(2017) Bei Liu et al.   Advanced Science

Soft X-ray activated NaYF4:Gd/Tb scintillating nanorods for in vivo dual-modal X-ray/X-ray-induced optical bioimaging

(2017) Xiaolong Li et al.   Nanoscale

Near-infrared photothermal/photodynamic therapy with indocyanine green induces apoptosis of hepatocellular carcinoma cells through oxidative stress

(2017) Chikara Shirata et al.   Scientific Reports

Co-Delivery of Cisplatin Prodrug and Chlorin e6 by Mesoporous Silica Nanoparticles for Chemo-Photodynamic Combination Therapy to Combat Drug Resistance

(2016) Wei Zhang et al.   ACS Applied Materials & Interfaces

Light-Responsive, Singlet-Oxygen-Triggered On-Demand Drug Release from Photosensitizer-Doped Mesoporous Silica Nanorods for Cancer Combination Therapy

(2016) Guangbao Yang et al.   ADVANCED FUNCTIONAL MATERIALS

Activatable albumin-photosensitizer nanoassemblies for triple-modal imaging and thermal-modulated photodynamic therapy of cancer

(2016) Dehong Hu et al.   BIOMATERIALS

Nanoscale metal−organic frameworks for combined photodynamic & radiation therapy in cancer treatment

(2016) Jingjing Liu et al.   BIOMATERIALS

An upconversion nanoplatform for simultaneous photodynamic therapy and Pt chemotherapy to combat cisplatin resistance

(2016) Fujin Ai et al.   DALTON TRANSACTIONS

A regional approach for CAR T-cell therapy for mesothelioma: from mouse models to clinical trial

(2016) Marissa Mayor et al.   Immunotherapy

Photodynamic Therapy Mediated by Nontoxic Core–Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer

(2016) Xiaopin Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

(2016) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

(2016) Dangge Wang et al.   NANO LETTERS

Toxicological and efficacy assessment of post-transition metal (Indium) phthalocyanine for photodynamic therapy in neuroblastoma

(2016) Monica Neagu et al.   Oncotarget

X-Ray Induced Photodynamic Therapy: A Combination of Radiotherapy and Photodynamic Therapy

(2016) Geoffrey D. Wang et al.   Theranostics

ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon Irradiation with a Single Light Source

(2016) Caixia Yue et al.   Theranostics

Near-Infrared Light Triggered ROS-activated Theranostic Platform based on Ce6-CPT-UCNPs for Simultaneous Fluorescence Imaging and Chemo-Photodynamic Combined Therapy

(2016) Caixia Yue et al.   Theranostics

Beyond the Barriers of Light Penetration: Strategies, Perspectives and Possibilities for Photodynamic Therapy

(2016) Srivalleesha Mallidi et al.   Theranostics

Enhanced Anti-Tumor Efficacy through a Combination of Integrin αvβ6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition

(2016) Liquan Gao et al.   Theranostics

Calcium phosphate-based organic–inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy

(2016) Takahiro Nomoto et al.   Biomaterials Science

Fluorene–morpholine-based organic nanoparticles: lysosome-targeted pH-triggered two-photon photodynamic therapy with fluorescence switch on–off

(2016) Moumita Gangopadhyay et al.   Journal of Materials Chemistry B

Intranuclear biophotonics by smart design of nuclear-targeting photo-/radio-sensitizers co-loaded upconversion nanoparticles

(2015) Wenpei Fan et al.   BIOMATERIALS

Combination of Photodynamic Therapy and Specific Immunotherapy Efficiently Eradicates Established Tumors

(2015) J. W. Kleinovink et al.   CLINICAL CANCER RESEARCH

ROS-dependent signal transduction

(2015) Colleen R Reczek et al.   CURRENT OPINION IN CELL BIOLOGY

Enhanced in vitro photocytotoxicity of water-soluble dendritic pheophorbide-a

(2015) Eun Ji Lee et al.   JOURNAL OF PORPHYRINS AND PHTHALOCYANINES

Improvement of DC vaccine with ALA-PDT induced immunogenic apoptotic cells for skin squamous cell carcinoma

(2015) Jie Ji et al.   Oncotarget

DC vaccine generated by ALA-PDT-induced immunogenic apoptotic cells for skin squamous cell carcinoma

(2015) Jie Ji et al.   OncoImmunology

X-ray-Induced Shortwave Infrared Biomedical Imaging Using Rare-Earth Nanoprobes

(2014) Dominik Jan Naczynski et al.   NANO LETTERS

Near-infrared light triggered photodynamic therapy in combination with gene therapy using upconversion nanoparticles for effective cancer cell killing

(2014) Xin Wang et al.   Nanoscale

Two combined photosensitizers: a goal for more effective photodynamic therapy of cancer

(2014) P Acedo et al.   Cell Death & Disease

Photodynamic therapy–generated cancer vaccine elicits acute phase and hormonal response in treated mice

(2012) Mladen Korbelik et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY