A Highly‐Efficient Type I Photosensitizer with Robust Vascular‐Disruption Activity for Hypoxic‐and‐Metastatic Tumor Specific Photodynamic Therapy

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

(2019) Sofia Gkountela et al.   CELL

Superoxide Radical Photogenerator with Amplification Effect: Surmounting the Achilles’ heels of Photodynamic Oncotherapy

(2019) Mingle Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness

(2019) Fei Peng et al.   Nature Nanotechnology

Poly(amidoamine) Dendrimer-Coordinated Copper(II) Complexes as a Theranostic Nanoplatform for the Radiotherapy-Enhanced Magnetic Resonance Imaging and Chemotherapy of Tumors and Tumor Metastasis

(2019) Yu Fan et al.   NANO LETTERS

Titanium-Based Nanoscale Metal–Organic Framework for Type I Photodynamic Therapy

(2019) Guangxu Lan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional nanoparticles based on a polymeric copper chelator for combination treatment of metastatic breast cancer

(2019) Ping Zhou et al.   BIOMATERIALS

Towards novel photodynamic anticancer agents generating superoxide anion radicals: A cyclometalated Ir(III) complex conjugated to a far-red emitting coumarin

(2019) Vojtech Novohradsky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selectively Potentiating Hypoxia Levels by Combretastatin A4 Nanomedicine: Toward Highly Enhanced Hypoxia-Activated Prodrug Tirapazamine Therapy for Metastatic Tumors

(2019) Shengcai Yang et al.   ADVANCED MATERIALS

A Bacteriochlorin‐Based Metal–Organic Framework Nanosheet Superoxide Radical Generator for Photoacoustic Imaging‐Guided Highly Efficient Photodynamic Therapy

(2019) Kai Zhang et al.   Advanced Science

Photo-triggered gadofullerene: enhanced cancer therapy by combining tumor vascular disruption and stimulation of anti-tumor immune responses

(2019) Mirong Guan et al.   BIOMATERIALS

Photothermal-pH-hypoxia responsive multifunctional nanoplatform for cancer photo-chemo therapy with negligible skin phototoxicity

(2019) Dapeng Chen et al.   BIOMATERIALS

Three-year lifetime and regeneration of superoxide radicals on the surface of hybrid TiO2 materials exposed to air

(2019) Domenico Pirozzi et al.   JOURNAL OF HAZARDOUS MATERIALS

Anti-angiogenic treatment (Bevacizumab) improves the responsiveness of photodynamic therapy in colorectal cancer

(2018) Cheng-Liang Peng et al.   Photodiagnosis and Photodynamic Therapy

Achieving efficient photodynamic therapy under both normoxia and hypoxia using cyclometalated Ru(ii) photosensitizer through type I photochemical process

(2018) Zhuang Lv et al.   Chemical Science

Sandwich-Like Fibers/Sponge Composite Combining Chemotherapy and Hemostasis for Efficient Postoperative Prevention of Tumor Recurrence and Metastasis

(2018) Zhiyun Zhang et al.   ADVANCED MATERIALS

Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors

(2018) Mingle Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis, spectroscopic properties and photodynamic activity of two cationic BODIPY derivatives with application in the photoinactivation of microorganisms

(2017) Maximiliano L. Agazzi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

pH-responsive polymeric micelles based on poly(ethyleneglycol)- b -poly(2-(diisopropylamino) ethyl methacrylate) block copolymer for enhanced intracellular release of anticancer drugs

(2017) Zhigang Xu et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer

(2017) Jonghoon Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxygenic Hybrid Semiconducting Nanoparticles for Enhanced Photodynamic Therapy

(2017) Houjuan Zhu et al.   NANO LETTERS

Use of Systemic Therapy Concurrent With Cranial Radiotherapy for Cerebral Metastases of Solid Tumors

(2017) Maikel Verduin et al.   ONCOLOGIST

Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

(2017) Guangbao Yang et al.   Nature Communications

Enhanced Photodynamic Cancer Treatment by Mitochondria-Targeting and Brominated Near-Infrared Fluorophores

(2017) Ilkoo Noh et al.   Advanced Science

Black Phosphorus Nanosheet-Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer

(2016) Wansong Chen et al.   ADVANCED MATERIALS

A Mitochondria-Targeted Photosensitizer Showing Improved Photodynamic Therapy Effects Under Hypoxia

(2016) Wen Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

(2016) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Overcoming the Achilles' heel of photodynamic therapy

(2016) Wenpei Fan et al.   CHEMICAL SOCIETY REVIEWS

Linking the future of anticancer metal-complexes to the therapy of tumour metastases

(2015) Alberta Bergamo et al.   CHEMICAL SOCIETY REVIEWS

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

(2015) Yuhao Cheng et al.   Nature Communications

Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models

(2015) Haibo Shao et al.   Oncotarget

Tumor Metastasis Inhibition by Imaging-Guided Photothermal Therapy with Single-Walled Carbon Nanotubes

(2014) Chao Liang et al.   ADVANCED MATERIALS

Nanoparticle Delivered Vascular Disrupting Agents (VDAs): Use of TNF-Alpha Conjugated Gold Nanoparticles for Multimodal Cancer Therapy

(2013) Mithun M. Shenoi et al.   MOLECULAR PHARMACEUTICS

DNA Photocleavage by a Cationic BODIPY Dye through Both Singlet Oxygen and Hydroxyl Radical: New Insight into the Photodynamic Mechanism of BODIPYs

(2012) Jianguang Wang  et al.   CHEMPHYSCHEM

Vascular targeted therapies in oncology

(2008) Dietmar W. Siemann et al.   CELL AND TISSUE RESEARCH

Modulation of in Vivo Tumor Radiation Response via Gold Nanoshell-Mediated Vascular-Focused Hyperthermia: Characterizing an Integrated Antihypoxic and Localized Vascular Disrupting Targeting Strategy

(2008) Parmeswaran Diagaradjane et al.   NANO LETTERS

Tumor Angiogenesis

(2008) Robert S. Kerbel   NEW ENGLAND JOURNAL OF MEDICINE