Molecular Engineering to Boost AIE-Active Free Radical Photogenerators and Enable High-Performance Photodynamic Therapy under Hypoxia

Superoxide Radical Photogenerator with Amplification Effect: Surmounting the Achilles’ heels of Photodynamic Oncotherapy

(2019) Mingle Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intriguing “chameleon” fluorescent bioprobes for the visualization of lipid droplet-lysosome interplay

(2019) Rong Hu et al.   BIOMATERIALS

The effectiveness and safety of X-PDT for cutaneous squamous cell carcinoma and melanoma

(2019) Lei Shi et al.   Nanomedicine

X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors

(2019) Samana Shrestha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuning Organelle Specificity and Photodynamic Therapy Efficiency by Molecular Function Design

(2019) Zhiyang Liu et al.   ACS Nano

Drug delivery micelles with efficient near-infrared photosensitizer for combined image-guided photodynamic therapy and chemotherapy of drug-resistant cancer

(2019) Shijie Zhen et al.   BIOMATERIALS

Aggregation-Induced Emission (AIE) Dots: Emerging Theranostic Nanolights

(2018) Guangxue Feng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Activatable Semiconducting Theranostics: Simultaneous Generation and Ratiometric Photoacoustic Imaging of Reactive Oxygen Species In Vivo

(2018) Zhen Yang et al.   ADVANCED MATERIALS

Corannulene-Incorporated AIE Nanodots with Highly Suppressed Nonradiative Decay for Boosted Cancer Phototheranostics In Vivo

(2018) Xinggui Gu et al.   ADVANCED MATERIALS

Metal-Organic-Framework-Assisted In Vivo Bacterial Metabolic Labeling and Precise Antibacterial Therapy

(2018) Duo Mao et al.   ADVANCED MATERIALS

Innovative Strategies for Hypoxic-Tumor Photodynamic Therapy

(2018) Xingshu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intermolecular Charge-Transfer Transition Emitter Showing Thermally Activated Delayed Fluorescence for Efficient Non-Doped OLEDs

(2018) Yi-Zhong Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Light-Up Probe with Aggregation-Induced Emission for Real-Time Bio-orthogonal Tumor Labeling and Image-Guided Photodynamic Therapy

(2018) Fang Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly photostable, lysosome-targeted BODIPYs with green to near-infrared emission for lysosome imaging in living cells

(2018) Zhuo Ye et al.   DYES AND PIGMENTS

Organic solar cells based on non-fullerene acceptors

(2018) Jianhui Hou et al.   NATURE MATERIALS

Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

(2018) Ji Qi et al.   Nature Communications

Highly Efficient Photosensitizers with Far-Red/Near-Infrared Aggregation-Induced Emission for In Vitro and In Vivo Cancer Theranostics

(2018) Dong Wang et al.   ADVANCED MATERIALS

Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy

(2018) Ying Zhou et al.   JOURNAL OF CONTROLLED RELEASE

Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors

(2018) Mingle Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer

(2017) Jonghoon Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke

(2017) Yanlan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ionization and Anion−π+ Interaction: A New Strategy for Structural Design of Aggregation-Induced Emission Luminogens

(2017) Jianguo Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acid-induced chemoselective arylthiolations of electron-rich arenes in ionic liquids from sodium arylsulfinates: the reducibility of halide anions in [Hmim]Br

(2017) Zhu-bing Xu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Self-Supplying O2 through the Catalase-Like Activity of Gold Nanoclusters for Photodynamic Therapy against Hypoxic Cancer Cells

(2017) Ching-Ping Liu et al.   Small

Simulated Sunlight-Mediated Photodynamic Therapy for Melanoma Skin Cancer by Titanium-Dioxide-Nanoparticle-Gold-Nanocluster-Graphene Heterogeneous Nanocomposites

(2017) Yan Cheng et al.   Small

Tumor-selective catalytic nanomedicine by nanocatalyst delivery

(2017) Minfeng Huo et al.   Nature Communications

Naphtho[2,3-c][1,2,5]thiadiazole and 2H-Naphtho[2,3-d][1,2,3]triazole-Containing D–A−π–A Conjugated Organic Dyes for Dye-Sensitized Solar Cells

(2016) Yung-Sheng Yen et al.   ACS Applied Materials & Interfaces

Efficient Charge Transfer and Fine-Tuned Energy Level Alignment in a THF-Processed Fullerene-Free Organic Solar Cell with 11.3% Efficiency

(2016) Zhong Zheng et al.   ADVANCED MATERIALS

A Mitochondrion-Specific Photoactivatable Fluorescence Turn-On AIE-Based Bioprobe for Localization Super-Resolution Microscope

(2016) Xinggui Gu et al.   ADVANCED MATERIALS

Intelligent Albumin-MnO2Nanoparticles as pH-/H2O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy

(2016) Qian Chen et al.   ADVANCED MATERIALS

Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging

(2016) Yongsheng Li et al.   ADVANCED MATERIALS

Perfluorocarbon-Loaded Hollow Bi2Se3Nanoparticles for Timely Supply of Oxygen under Near-Infrared Light to Enhance the Radiotherapy of Cancer

(2016) Guosheng Song et al.   ADVANCED MATERIALS

A New Modality for Cancer Treatment—Nanoparticle Mediated Microwave Induced Photodynamic Therapy

(2016) Mengyu Yao et al.   Journal of Biomedical Nanotechnology

Highly Effective Dual-Function Near-Infrared (NIR) Photosensitizer for Fluorescence Imaging and Photodynamic Therapy (PDT) of Cancer

(2016) Nayan Patel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Use of fluorescent probes for ROS to tease apart Type I and Type II photochemical pathways in photodynamic therapy

(2016) Maria Garcia-Diaz et al.   METHODS

Enabling singlet fission by controlling intramolecular charge transfer in π-stacked covalent terrylenediimide dimers

(2016) Eric A. Margulies et al.   Nature Chemistry

Recent advances in twisted intramolecular charge transfer (TICT) fluorescence and related phenomena in materials chemistry

(2016) Shunsuke Sasaki et al.   Journal of Materials Chemistry C

Rational Molecular Design for Achieving Persistent and Efficient Pure Organic Room-Temperature Phosphorescence

(2016) Weijun Zhao et al.   Chem

Titania Coated Upconversion Nanoparticles for Near-Infrared Light Triggered Photodynamic Therapy

(2015) Sasidharan Swarnalatha Lucky et al.   ACS Nano

Achieving a Significantly Increased Efficiency in Nondoped Pure Blue Fluorescent OLED: A Quasi-Equivalent Hybridized Excited State

(2015) Shitong Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy

(2015) Huaiyi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aggregation-Induced Emission: Together We Shine, United We Soar!

(2015) Ju Mei et al.   CHEMICAL REVIEWS

Thermally Activated Delayed Fluorescence from Azasiline Based Intramolecular Charge-Transfer Emitter (DTPDDA) and a Highly Efficient Blue Light Emitting Diode

(2015) Jin Won Sun et al.   CHEMISTRY OF MATERIALS

H2O2-Activatable and O2-Evolving Nanoparticles for Highly Efficient and Selective Photodynamic Therapy against Hypoxic Tumor Cells

(2015) Huachao Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics

(2015) Shidang Xu et al.   Chemical Science

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

(2015) Yuhao Cheng et al.   Nature Communications

Marriage of Scintillator and Semiconductor for Synchronous Radiotherapy and Deep Photodynamic Therapy with Diminished Oxygen Dependence

(2014) Chen Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

(2014) Yongqiang Chen et al.   Autophagy

A dual functional AEE fluorogen as a mitochondrial-specific bioprobe and an effective photosensitizer for photodynamic therapy

(2014) Engui Zhao et al.   CHEMICAL COMMUNICATIONS

Quantum-Chemical Predictions of pKa’s of Thiols in DMSO

(2014) Hai-Zhu Yu et al.   JOURNAL OF PHYSICAL CHEMISTRY A

X-ray-induced nanoparticle-based photodynamic therapy of cancer

(2014) Xiaoju Zou et al.   Nanomedicine

Investigating the optimal size of anticancer nanomedicine

(2014) L. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced proportion of radiative excitons in non-doped electro-fluorescence generated from an imidazole derivative with an orthogonal donor–acceptor structure

(2013) Shitong Zhang et al.   CHEMICAL COMMUNICATIONS

Twisted Intramolecular Charge Transfer State for Long-Wavelength Thermally Activated Delayed Fluorescence

(2013) Hiroyuki Tanaka et al.   CHEMISTRY OF MATERIALS

Mechanism of Photogenerated Reactive Oxygen Species and Correlation with the Antibacterial Properties of Engineered Metal-Oxide Nanoparticles

(2012) Yang Li et al.   ACS Nano

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

(2012) Niagara Muhammad Idris et al.   NATURE MEDICINE

Use of Size and a Copolymer Design Feature To Improve the Biodistribution and the Enhanced Permeability and Retention Effect of Doxorubicin-Loaded Mesoporous Silica Nanoparticles in a Murine Xenograft Tumor Model

(2011) Huan Meng et al.   ACS Nano

Aggregation-induced emission

(2011) Yuning Hong et al.   CHEMICAL SOCIETY REVIEWS

Activating efficient phosphorescence from purely organic materials by crystal design

(2011) Onas Bolton et al.   Nature Chemistry

Mechanisms of Singlet-Oxygen and Superoxide-Ion Generation by Porphyrins and Bacteriochlorins and their Implications in Photodynamic Therapy

(2010) Elsa F. F. Silva et al.   CHEMISTRY-A EUROPEAN JOURNAL