Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration

Design of nanocarriers based on complex biological barriers in vivo for tumor therapy

(2017) Junjie Liu et al.   Nano Today

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

(2017) Alexander C. Huang et al.   NATURE

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

(2017) Enfu Hui et al.   SCIENCE

Recent progress in development of siRNA delivery vehicles for cancer therapy

(2016) Hyun Jin Kim et al.   ADVANCED DRUG DELIVERY REVIEWS

An O2Self-Sufficient Biomimetic Nanoplatform for Highly Specific and Efficient Photodynamic Therapy

(2016) Hong Cheng et al.   ADVANCED FUNCTIONAL MATERIALS

Photosensitizer enhanced disassembly of amphiphilic micelle for ROS-response targeted tumor therapy in vivo

(2016) Liangliang Dai et al.   BIOMATERIALS

Photodynamic Therapy Mediated by Nontoxic Core–Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer

(2016) Xiaopin Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Integrated Nano-Platform for Breaking the Barrier between Chemotherapy and Immunotherapy

(2016) Di-Wei Zheng et al.   NANO LETTERS

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

(2016) Dangge Wang et al.   NANO LETTERS

Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System

(2016) Xiuwen Guan et al.   NANO LETTERS

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

(2016) Chunbai He et al.   Nature Communications

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Dendrimerlike Mesoporous Silica Nanoparticles as pH-Responsive Nanocontainers for Targeted Drug Delivery and Bioimaging

(2015) Liangliang Dai et al.   ACS Applied Materials & Interfaces

Charge-Controlled Nanoprecipitation as a Modular Approach to Ultrasmall Polymer Nanocarriers: Making Bright and Stable Nanoparticles

(2015) Andreas Reisch et al.   ACS Nano

The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment

(2015) Jinqiang Wang et al.   ACS Nano

Surface Functionalization of Nanoparticles with Polyethylene Glycol: Effects on Protein Adsorption and Cellular Uptake

(2015) Beatriz Pelaz et al.   ACS Nano

A Peptide-Network Weaved Nanoplatform with Tumor Microenvironment Responsiveness and Deep Tissue Penetration Capability for Cancer Therapy

(2015) Ya Liu et al.   ADVANCED MATERIALS

Facile Generation of Tumor-pH-Labile Linkage-Bridged Block Copolymers for Chemotherapeutic Delivery

(2015) Chun-Yang Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

(2015) Sonja Kleffel et al.   CELL

Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance

(2015) Tuo Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Coinhibitory molecule PD-1 as a potential target for the immunotherapy of multiple myeloma

(2013) D Atanackovic et al.   LEUKEMIA

Cancer Immunotherapy

(2013) M. McNutt   SCIENCE

A Targeted and FRET-Based Ratiometric Fluorescent Nanoprobe for Imaging Mitochondrial Hydrogen Peroxide in Living Cells

(2013) Fangkai Du et al.   Small

The Challenge To Relate the Physicochemical Properties of Colloidal Nanoparticles to Their Cytotoxicity

(2012) Pilar Rivera-Gil et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nucleic Acid Delivery: The Missing Pieces of the Puzzle?

(2012) Juliane Nguyen et al.   ACCOUNTS OF CHEMICAL RESEARCH

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

(2012) Niagara Muhammad Idris et al.   NATURE MEDICINE

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

(2012) S. Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin

(2011) Xiao-Bing Xiong et al.   ACS Nano

Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design

(2011) Kevin Buyens et al.   JOURNAL OF CONTROLLED RELEASE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma

(2010) Ryosuke Hino et al.   CANCER

The Therapeutic Effect of Anti-HER2/neu Antibody Depends on Both Innate and Adaptive Immunity

(2010) SaeGwang Park et al.   CANCER CELL

T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

(2009) Natalia Martin-Orozco et al.   IMMUNITY

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Immune Therapy for Cancer

(2008) Michael Dougan et al.   Annual Review of Immunology

Cancer Immunotherapy by Dendritic Cells

(2008) Cornelis J.M. Melief   IMMUNITY

Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model

(2008) A. P. Castano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA