Construction of homo and heteronuclear Ru(II), Ir(III) and Re(I) complexes for target specific cancer therapy
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Construction of homo and heteronuclear Ru(II), Ir(III) and Re(I) complexes for target specific cancer therapy
Authors
Keywords
Homonuclear, Heteronuclear, Ru(II)/Ir(III)/Re(I), Target specificity, Cancer therapy
Journal
COORDINATION CHEMISTRY REVIEWS
Volume 460, Issue -, Pages 214462
Publisher
Elsevier BV
Online
2022-02-21
DOI
10.1016/j.ccr.2022.214462
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Recent advances in biological activities of rhodium complexes: Their applications in drug discovery research
- (2021) Marzieh Sohrabi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Monodentately-coordinated bioactive moieties in multimodal half-sandwich organoruthenium anticancer agents
- (2021) Tasha R. Steel et al. COORDINATION CHEMISTRY REVIEWS
- Induction and Monitoring of DNA Phase Separation in Living Cells by a Light-Switching Ruthenium Complex
- (2021) Wen-Jin Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Bivalent chromatin as a therapeutic target in cancer: An in silico predictive approach for combining epigenetic drugs
- (2021) Tomás Alarcón et al. PLoS Computational Biology
- Photodynamic therapy with mitochondria-targeted biscyclometallated Ir(iii) complexes. Multi-action mechanism and strong influence of the cyclometallating ligand
- (2021) Elisenda Zafon et al. DALTON TRANSACTIONS
- pH-Responsive N^C-Cyclometalated Iridium(III) Complexes: Synthesis, Photophysical Properties, Computational Results, and Bioimaging Application
- (2021) Anastasia I. Solomatina et al. MOLECULES
- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Ruthenium(II)/Benzonitrile Complex Induces Cytotoxic Effect in Sarcoma-180 Cells by Caspase-Mediated and Tp53/p21-Mediated Apoptosis, with Moderate Brine Shrimp Toxicity
- (2020) Raquel Santos Faria et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Rhenium-Based Complexes and in Vivo Testing: A Brief History
- (2020) Miles S. Capper et al. CHEMBIOCHEM
- Synthesis, Characterization, Cytotoxic Activity, and Metabolic Studies of Ruthenium(II) Polypyridyl Complexes Containing Flavonoid Ligands
- (2020) Alexandra-Cristina Munteanu et al. INORGANIC CHEMISTRY
- Effect of N,N Coordination and RuII Halide Bond in Enhancing Selective Toxicity of a Tyramine-Based RuII (p-Cymene) Complex
- (2020) Arpan Mukherjee et al. INORGANIC CHEMISTRY
- Structurally Strained Half-Sandwich Iridium(III) Complexes As Highly Potent Anticancer Agents
- (2020) Ana C. Carrasco et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Structure of Arene Ru(II) N∧O-Chelating Complexes: In Vitro Cytotoxicity and Cancer Cell Death Mechanism
- (2020) Sundarraman Balaji et al. ORGANOMETALLICS
- Recoding the Cancer Epigenome by Intervening in Metabolism and Iron Homeostasis with Mitochondria‐Targeted Rhenium(I) Complexes
- (2020) Zheng‐Yin Pan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Recent advances of iridium(III) metallophosphors for health-related applications
- (2020) Po-Yu Ho et al. COORDINATION CHEMISTRY REVIEWS
- Advances in Novel Iridium (III) Based Complexes for Anticancer Applications: A Review
- (2020) S Ajay Sharma et al. INORGANICA CHIMICA ACTA
- Tetrazole functional copolymers: Facile access to well-defined Rhenium(I)-Polymeric luminescent materials
- (2020) Elena Dallerba et al. POLYMER
- Identification of novel potent and non-toxic anticancer, anti-angiogenic and antimetastatic rhenium complexes against colorectal carcinoma
- (2020) Joachim Delasoie et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent advances in cytotoxicity, cellular uptake and mechanism of action of ruthenium metallodrugs: A review
- (2020) P Sudhindra et al. POLYHEDRON
- A review on homo multinuclear anticancer Metallotherapuetics
- (2020) Sudhindra Pete et al. INORGANICA CHIMICA ACTA
- Enhancement of photodynamic cancer therapy by physical and chemical factors
- (2019) Mingying Yang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The rhenium(I)-diselenoether anticancer drug targets ROS, TGF-β1, VEGF-A, and IGF-1 in an in vitro experimental model of triple-negative breast cancers
- (2019) Philippe Collery et al. INVESTIGATIONAL NEW DRUGS
- Anticancer Cyclometalated Iridium(III) Complexes with Planar Ligands: Mitochondrial DNA Damage and Metabolism Disturbance
- (2019) Jian-Jun Cao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Combinatorial Synthesis to Identify a Potent, Necrosis-Inducing Rhenium Anticancer Agent
- (2019) Chilaluck C. Konkankit et al. INORGANIC CHEMISTRY
- Mitochondria-Accumulating Rhenium(I) Tricarbonyl Complexes Induce Cell Death via Irreversible Oxidative Stress and Glutathione Metabolism Disturbance
- (2019) Fang-Xin Wang et al. ACS Applied Materials & Interfaces
- Serendipitous Synthesis of Five-Coordinated Half-Sandwich Aminoimine Iridium(III) and Ruthenium(II) Complexes and Their Application as Potent Anticancer Agents
- (2019) Qing Du et al. INORGANIC CHEMISTRY
- Organometallic rhenium tricarbonyl–enrofloxacin and –levofloxacin complexes: synthesis, albumin-binding, DNA-interaction and cell viability studies
- (2019) Chaido-Christina Pagoni et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Synthesis, spectral studies, DNA binding, photocleavage, antimicrobial and anticancer activities of isoindol Ru(II) polypyridyl complexes
- (2019) Ch. Ravi et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Synthesis, Structure, Stability, and Inhibition of Tubulin Polymerization by RuII–p-Cymene Complexes of Trimethoxyaniline-Based Schiff Bases
- (2019) Sourav Acharya et al. INORGANIC CHEMISTRY
- Triphenylamine-appended cycloiridium(III) complexes: Preparation, photophysical properties and application in biology/luminescence imaging
- (2019) Xicheng Liu et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Half‐sandwich Ruthenium (II) complexes with triphenylamine modified dipyridine skeleton and application in biology/luminescence imaging
- (2019) Xingxing Ge et al. APPLIED ORGANOMETALLIC CHEMISTRY
- Design of Rhenium Compounds in Targeted Anticancer Therapeutics
- (2019) Philippe Collery et al. CURRENT PHARMACEUTICAL DESIGN
- Studies of anticancer activity in vitro and in vivo of iridium(III) polypyridyl complexes-loaded liposomes as drug delivery system
- (2019) Wen-Yao Zhang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Anticancer Effect Studies of Iridium(III) Polypyridyl Complexes against SGC-7901 Cells
- (2019) Li-Xia Zhang et al. MOLECULES
- Guanidine-modified cyclometalated iridium(III) complexes for mitochondria-targeted imaging and photodynamic therapy
- (2019) Xing-Dong Song et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, Characterization, and Biological Properties of Steroidal Ruthenium(II) and Iridium(III) Complexes Based on the Androst-16-en-3-ol Framework
- (2019) Vanessa Koch et al. INORGANIC CHEMISTRY
- Synthesis and investigation of a tris-cyclometalated iridium complex bearing a single quarternary ammonium group
- (2019) Sureemas Meksawangwong et al. INORGANICA CHIMICA ACTA
- Ruthenium arene complex induces cell cycle arrest and apoptosis through activation of P53-mediated signaling pathways
- (2019) Jianfu Zhao et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Rhenium(I) polypyridine complexes coordinated to an ethyl-isonicotinate ligand: Luminescence and in vitro anti-cancer studies
- (2019) Luiz D. Ramos et al. INORGANICA CHIMICA ACTA
- Synthesis, characterization, and biological properties of rhenium(I) tricarbonyl complexes bearing nitrogen-donor ligands
- (2019) Brendan L. Murphy et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Making the Right Link to Theranostics: The Photophysical and Biological Properties of Dinuclear RuII–ReI dppz Complexes Depend on Their Tether
- (2019) Hiwa K. Saeed et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ruthenium (II) complexes with N, O-chelating proline and threonine ligands cause selective cytotoxicity by the induction of genomic instability, cell cycle arrest and apoptosis in breast and prostate tumor cells
- (2019) Israel Higino de Sousa et al. TOXICOLOGY IN VITRO
- Cell-based studies of the first-in-class half-sandwich Ir(III) complex containing histone deacetylase inhibitor 4-phenylbutyrate
- (2018) Pavel Štarha et al. APPLIED ORGANOMETALLIC CHEMISTRY
- Triphenylamine-Appended Half-Sandwich Iridium(III) Complexes and Their Biological Applications
- (2018) Xiangdong He et al. Chemistry-An Asian Journal
- N- and S-donor leaving groups in triazole-based ruthena(ii)cycles: potent anticancer activity, selective activation, and mode of action studies
- (2018) Christoph A. Riedl et al. DALTON TRANSACTIONS
- New organometallic imines of rhenium(i) as potential ligands of GSK-3β: synthesis, characterization and biological studies
- (2018) Michelle Muñoz-Osses et al. DALTON TRANSACTIONS
- Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium
- (2018) Chilaluck C. Konkankit et al. DALTON TRANSACTIONS
- Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential
- (2018) Leonor Côrte-Real et al. INORGANIC CHEMISTRY
- Half-Sandwich Iridium(III) and Ruthenium(II) Complexes Containing P^P-Chelating Ligands: A New Class of Potent Anticancer Agents with Unusual Redox Features
- (2018) JuanJuan Li et al. INORGANIC CHEMISTRY
- Photolabile ruthenium complexes to cage and release a highly cytotoxic anticancer agent
- (2018) Jianhua Wei et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?
- (2018) Sreekanth Thota et al. JOURNAL OF MEDICINAL CHEMISTRY
- Induction of the Endoplasmic Reticulum Stress Pathway by Highly Cytotoxic Organoruthenium Schiff-Base Complexes
- (2018) Mun Juinn Chow et al. MOLECULAR PHARMACEUTICS
- Studies on the DNA binding and anticancer activity of Ru(ii) polypyridyl complexes by using a (2-(4-(diethoxymethyl)-1H-imidazo[4,5-f][1,10] phenanthroline)) intercalative ligand
- (2018) Ravi Kumar Vuradi et al. NEW JOURNAL OF CHEMISTRY
- One-pot reaction of amide functionalized Re(I) based dinuclear metallacycles: Synthesis, characterization and evaluation for anticancer potential
- (2018) R. Govindarajan et al. POLYHEDRON
- Phosphine/diimine ruthenium complexes with Cl − , CO, NO + , NO 2 − , NO 3 − and pyridine ligands: Pro-apoptotic activity on triple-negative breast cancer cells and DNA/HSA interactions
- (2018) Henrique Vieira Reis Silva et al. POLYHEDRON
- A cyclometalated iridium(III) complex induces apoptosis and autophagy through inhibition of the PI3K/AKT/mTOR pathway
- (2018) Zhen-Hua Liang et al. TRANSITION METAL CHEMISTRY
- A comparative study on in vitro cytotoxicity, cellular uptake, localization and apoptosis-inducing mechanism of two ruthenium(II) complexes
- (2018) Jincan Chen et al. TRANSITION METAL CHEMISTRY
- Mitochondria-targeted half-sandwich rutheniumII diimine complexes: anticancer and antimetastasis via ROS-mediated signalling
- (2018) Zhishan Xu et al. Inorganic Chemistry Frontiers
- Rhenium-Carbonyl-Based Supramolecular Coordination Complexes: Synthesis, Structure and Properties
- (2018) Deepak Gupta et al. ChemistrySelect
- Influence of the substituent on the phosphine ligand in novel rhenium(i) aldehydes. Synthesis, computational studies and first insights into the antiproliferative activity
- (2018) Michelle Muñoz-Osses et al. DALTON TRANSACTIONS
- Synthesis and antitumour evaluation of mono- and multinuclear [2+1] tricarbonylrhenium(I) complexes
- (2018) Dylan Giffard et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Lysosome-Targeted Chemotherapeutics: Half-Sandwich Ruthenium(II) Complexes That Are Selectively Toxic to Cancer Cells
- (2018) Zhenzhen Tian et al. INORGANIC CHEMISTRY
- Polynuclear ruthenium organometallic complexes containing a 1,3,5-triazine ligand: synthesis, DNA interaction, and biological activity
- (2018) Floyd A. Beckford et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Potent Half-Sandwich Iridium(III) and Ruthenium(II) Anticancer Complexes Containing a P^O-Chelated Ligand
- (2018) Qing Du et al. ORGANOMETALLICS
- Half-Sandwich Iridium and Ruthenium Complexes: Effective Tracking in Cells and Anticancer Studies
- (2018) JuanJuan Li et al. INORGANIC CHEMISTRY
- Strong Influence of Ancillary Ligands Containing Benzothiazole or Benzimidazole Rings on Cytotoxicity and Photoactivation of Ru(II) Arene Complexes
- (2018) Matteo Lari et al. INORGANIC CHEMISTRY
- Study of the cytotoxic and genotoxic potential of the carbonyl ruthenium(II) compound, ct- [RuCl(CO)(dppb)(bipy)]PF6 [dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2′-bipyridine], by in vitro and in vivo assays
- (2018) Andréa P. Carnizello et al. JOURNAL OF APPLIED TOXICOLOGY
- Half-sandwich iridium(III) complexes with α-picolinic acid frameworks and antitumor applications
- (2018) Hailong Hao et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Design, synthesis, and evaluation of fluorine and Naphthyridine–Based half-sandwich organoiridium/ruthenium complexes with bioimaging and anticancer activity
- (2018) JuanJuan Li et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Anticancer, Azonafide-Inspired Fluorescent Ligands and Their Rhenium(I) Complexes for Cellular Imaging
- (2017) Emily E. Langdon-Jones et al. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- Ruthenium(II)-Arene Metallacycles: Crystal Structures, Interaction with DNA, and Cytotoxicity
- (2017) Hong-Yan Wang et al. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- “Half-sandwich” Schiff-base Ir(III) complexes as anticancer agents
- (2017) Ze-dong Mou et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Ruthenium(II) complexes of saccharin with dipyridoquinoxaline and dipyridophenazine: Structures, biological interactions and photoinduced DNA damage activity
- (2017) Priyaranjan Kumar et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, characterization, cellular uptake and apoptosis-inducing properties of two highly cytotoxic cyclometalated ruthenium(II) β-carboline complexes
- (2017) Jincan Chen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and anticancer properties of ruthenium (II) complexes as potent apoptosis inducers through mitochondrial disruption
- (2017) Dan Wan et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Photobiological Activity of Ru(II) Dyads Derived from Pyrrole-2-carboxylate Thionoesters
- (2017) Deborah A. Smithen et al. INORGANIC CHEMISTRY
- New Class of Half-Sandwich Ruthenium(II) Arene Complexes Bearing the Water-Soluble CAP Ligand as an in Vitro Anticancer Agent
- (2017) Antonella Guerriero et al. INORGANIC CHEMISTRY
- Synthesis, characterization, DNA binding and cytotoxicity of fluoro-dipyrrin based arene ruthenium(II) complexes
- (2017) Rajendra Prasad Paitandi et al. INORGANICA CHIMICA ACTA
- Ruthenium(II)-arene complexes with dibenzoylmethane induce apoptotic cell death in multiple myeloma cell lines
- (2017) Riccardo Pettinari et al. INORGANICA CHIMICA ACTA
- The Differential Distribution of RAPTA-T in Non-Invasive and Invasive Breast Cancer Cells Correlates with Its Anti-Invasive and Anti-Metastatic Effects
- (2017) Ronald Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- New 4′-(4-chlorophenyl)-2,2′:6′,2″-terpyridine ruthenium(II) complexes: Synthesis, characterization, interaction with DNA/BSA and cytotoxicity studies
- (2017) Milan M. Milutinović et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- New ruthenium compounds bearing semicarbazone 2-formylopyridine moiety: Playing with auxiliary ligands for tuning the mechanism of biological activity
- (2017) Michał Łomzik et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Self-assembly of manganese(I) and rhenium(I) based semi-rigid ester functionalized M 2 L 2 -type metallacyclophanes: Synthesis, characterization and cytotoxicity evaluation
- (2017) Chowan Ashok Kumar et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- Mitochondria Targeted Protein-Ruthenium Photosensitizer for Efficient Photodynamic Applications
- (2017) Sabyasachi Chakrabortty et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In Vitro Anticancer Activity and in Vivo Biodistribution of Rhenium(I) Tricarbonyl Aqua Complexes
- (2017) Kevin M. Knopf et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Unprecedented anticancer activities of organorhenium sulfonato and carboxylato complexes against hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells
- (2017) Paul T. Wilder et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Mitochondria Targeting with Luminescent Rhenium(I) Complexes
- (2017) Joanna Skiba et al. MOLECULES
- Organometallic tosyl hydrazones: Synthesis, characterization, crystal structures and in vitro evaluation for anti- Mycobacterium tuberculosis and antiproliferative activities
- (2017) Camila Concha et al. POLYHEDRON
- The cancer epigenome: Concepts, challenges, and therapeutic opportunities
- (2017) Mark A. Dawson SCIENCE
- Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium(iii) complexes
- (2017) Jian-Jun Cao et al. Chemical Science
- Synthesis, Structural Characterization and Biological Evaluation of Rhenium(I) Tricarbonyl Complexes with β-Carboline Ligands.
- (2017) Iván Maisuls et al. ChemistrySelect
- Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity
- (2017) Robert H. Berndsen et al. Scientific Reports
- Ruthenium(II) complexes containing 4-methoxybenzhydrazone ligands: synthesis, characterization, DNA binding, DNA cleavage, radical scavenging andin vitrocytotoxic activity
- (2016) Maruthachalam Mohanraj et al. APPLIED ORGANOMETALLIC CHEMISTRY
- Cyclometalated iridium(III) complexes as mitochondria-targeted anticancer agents
- (2016) Kai Xiong et al. BIOCHIMIE
- Cationic Amphiphilic Tris-Cyclometalated Iridium(III) Complexes Induce Cancer Cell Death via Interaction with Ca2+-Calmodulin Complex
- (2016) Yosuke Hisamatsu et al. BIOCONJUGATE CHEMISTRY
- Synthesis, Characterization, and Biological Studies of a Piperidinyl Appended Dipicolylamine Ligand and Its Rhenium Tricarbonyl Complex as Potential Therapeutic Agents for Human Breast Cancer
- (2016) Amali Subasinghe et al. BIOINORGANIC CHEMISTRY AND APPLICATIONS
- Heterodinuclear Pt(iv)–Ru(ii) anticancer prodrugs to combat both drug resistance and tumor metastasis
- (2016) Lili Ma et al. CHEMICAL COMMUNICATIONS
- Overcoming the Achilles' heel of photodynamic therapy
- (2016) Wenpei Fan et al. CHEMICAL SOCIETY REVIEWS
- Synthesis and characterization of novel rhenium(I) complexes towards potential biological imaging applications
- (2016) Kokila Ranasinghe et al. Chemistry Central Journal
- Honeycomb-like Ordered Assembly of DNA Induced by Flexible Binuclear Ruthenium(II)-Polypyridyl Complexes
- (2016) Sushma B. Singh et al. CHEMISTRY-A EUROPEAN JOURNAL
- Mono- and Dinuclear Phosphorescent Rhenium(I) Complexes: Impact of Subcellular Localization on Anticancer Mechanisms
- (2016) Rui-Rong Ye et al. CHEMISTRY-A EUROPEAN JOURNAL
- Substituent effect and wavelength dependence of the photoinduced Ru–O homolysis in the [Ru(bpy)2(py-SO3)]+-type complexes
- (2016) Yue Zheng et al. DALTON TRANSACTIONS
- Dinuclear ruthenium(ii) complexes containing one inert metal centre and one coordinatively-labile metal centre: syntheses and biological activities
- (2016) Xin Li et al. DALTON TRANSACTIONS
- Coumarin-appended phosphorescent cyclometalated iridium(iii) complexes as mitochondria-targeted theranostic anticancer agents
- (2016) Rui-Rong Ye et al. DALTON TRANSACTIONS
- The induction of apoptosis in HepG-2 cells by ruthenium(II) complexes through an intrinsic ROS-mediated mitochondrial dysfunction pathway
- (2016) Chuan-Chuan Zeng et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Introducing the 4-Phenyl-1,2,3-Triazole Moiety as a Versatile Scaffold for the Development of Cytotoxic Ruthenium(II) and Osmium(II) Arene Cyclometalates
- (2016) Christoph A. Riedl et al. INORGANIC CHEMISTRY
- Synthesis, Characterization, and in Vitro Antitumor Activity of Ruthenium(II) Polypyridyl Complexes Tethering EGFR-Inhibiting 4-Anilinoquinazolines
- (2016) Jun Du et al. INORGANIC CHEMISTRY
- DNA Binding and Photocleavage Properties, Cellular Uptake and Localization, and in-Vitro Cytotoxicity of Dinuclear Ruthenium(II) Complexes with Varying Lengths in Bridging Alkyl Linkers
- (2016) Ping Liu et al. INORGANIC CHEMISTRY
- Synthesis, characterisation and cytotoxicity studies of Manganese(I) and Rhenium(I) based metallacrown ethers
- (2016) Chowan Ashok Kumar et al. INORGANIC CHEMISTRY COMMUNICATIONS
- Synthesis, characterization, and antitumor properties of ruthenium(II) anthraquinone complexes
- (2016) Jin-Quan Wang et al. JOURNAL OF COORDINATION CHEMISTRY
- Synthesis, characterization and biological evaluation of novel Ru(II)–arene complexes containing intercalating ligands
- (2016) Stefan Nikolić et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Biodistribution of the novel anticancer drug sodium trans -[tetrachloridobis(1 H -indazole)ruthenate(III)] KP-1339/IT139 in nude BALB/c mice and implications on its mode of action
- (2016) Anna K. Bytzek et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Synthesis, characterization, antiproliferative and molecular docking study of new half sandwich Ir(III), Rh(III) and Ru(II) complexes
- (2016) Saravanan Thangavel et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ruthenium(II) polypyridyl complexes with 1,8-naphthalimide group as DNA binder, photonuclease, and dual inhibitors of topoisomerases I and IIα
- (2016) Yanmei Sun et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex
- (2016) Viktor Brabec et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ru(II)/clotrimazole/diphenylphosphine/bipyridine complexes: Interaction with DNA, BSA and biological potential against tumor cell lines and Mycobacterium tuberculosis
- (2016) Legna Colina-Vegas et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- The studies on the cytotoxicity in vitro, cellular uptake, cell cycle arrest and apoptosis-inducing properties of ruthenium methylimidazole complex [Ru(MeIm)4(p-cpip)]2+
- (2016) Lan-mei Chen et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Synthesis, characterization and biological activities of some Ru(II) complexes with substituted chalcones and their applications as chemotherapeutics against breast cancer
- (2016) Ashok K. Singh et al. JOURNAL OF MOLECULAR STRUCTURE
- Inhibition of cancer cell growth by ruthenium complexes
- (2016) Joji Iida et al. Journal of Translational Medicine
- Recent Advances on Dark and Light-Activated Cytotoxity of Imidazole- Containing Ruthenium Complexes
- (2016) Ping Liu et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Tricarbonylrhenium(i) complexes with 2-acetylpyridine-derived hydrazones are cytotoxic to NCI-H460 human large cell lung cancer
- (2016) Camila Vargas Garcia et al. NEW JOURNAL OF CHEMISTRY
- The water soluble ruthenium(II) organometallic compound [Ru( p -cymene)(bis(3,5 dimethylpyrazol-1-yl)methane)Cl]Cl suppresses triple negative breast cancer growth by inhibiting tumor infiltration of regulatory T cells
- (2016) Maura Montani et al. PHARMACOLOGICAL RESEARCH
- Synthesis, cytotoxicity in vitro, apoptosis, cell cycle arrest and comet assay of asymmetry ruthenium(II) complexes
- (2016) Cheng Zhang et al. POLYHEDRON
- Use of 1,2,4-triazolo[1,5-a]pyrimidines to design new “piano-stool” ruthenium(II) compounds
- (2016) Iwona Łakomska et al. POLYHEDRON
- Synthesis, structures, and DNA and protein binding of ruthenium(ii)-p-cymene complexes of substituted pyridylimidazo[1,5-a]pyridine: enhanced cytotoxicity of complexes of ligands appended with a carbazole moiety
- (2016) Themmila Khamrang et al. RSC Advances
- Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer
- (2016) Matthew Dickerson et al. Journal of Materials Chemistry B
- Antimetastatic activity of novel ruthenium (III) pyridine complexes
- (2016) Liwei Gu et al. Cancer Medicine
- Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy
- (2015) Huaiyi Huang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis, characterization and catalytic, cytotoxic and antimicrobial activities of two novel cyclotriphosphazene-based multisite ligands and their Ru(II) complexes
- (2015) Diğdem Erdener Çıralı et al. APPLIED ORGANOMETALLIC CHEMISTRY
- Ruthenium(II) polypyridyl complexes as mitochondria-targeted two-photon photodynamic anticancer agents
- (2015) Jiangping Liu et al. BIOMATERIALS
- Cyclometalated Ruthenium(II) Anthraquinone Complexes Exhibit Strong Anticancer Activity in Hypoxic Tumor Cells
- (2015) Leli Zeng et al. CHEMISTRY-A EUROPEAN JOURNAL
- A Cytostatic Ruthenium(II)-Platinum(II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up-regulating p27KIP1
- (2015) Vadde Ramu et al. CHEMISTRY-A EUROPEAN JOURNAL
- Two novel BODIPY–Ru(ii) arene dyads enabling effective photo-inactivation against cancer cells
- (2015) Tianji Wang et al. DALTON TRANSACTIONS
- Synthesis, characterization and biological evaluation of mixed-ligand ruthenium(ii) complexes for photodynamic therapy
- (2015) Huaiyi Huang et al. DALTON TRANSACTIONS
- Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(ii)-polypyridyl conjugates
- (2015) Gary J. Ryan et al. DALTON TRANSACTIONS
- Lipophilicity-dependent ruthenium N-heterocyclic carbene complexes as potential anticancer agents
- (2015) Gaochao Lv et al. DALTON TRANSACTIONS
- Ruthenium(II)-arene complexes with naphthalimide-tagged N,O- and N,N-chelating ligands: Synthesis and biological evaluation
- (2015) Kesete Ghebreyessus et al. INORGANICA CHIMICA ACTA
- Interaction of rhenium(I) complex carrying long alkyl chain with Calf Thymus DNA: Cytotoxic and cell imaging studies
- (2015) Gopalakrishnan Balakrishnan et al. INORGANICA CHIMICA ACTA
- Antitumor activity of a rhenium (I)-diselenoether complex in experimental models of human breast cancer
- (2015) Philippe Collery et al. INVESTIGATIONAL NEW DRUGS
- Synthesis, characterization and DNA-binding properties of Ru(II) complexes coordinated by ofloxacin as potential antitumor agents
- (2015) Chengxi Wang et al. JOURNAL OF COORDINATION CHEMISTRY
- The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds
- (2015) Leonor Côrte-Real et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Selective nuclei accumulation of ruthenium(II) complex enantiomers that target G-quadruplex DNA
- (2015) Dongdong Sun et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- The 1,3-diaryltriazenido( p -cymene)ruthenium(II) complexes with a high in vitro anticancer activity
- (2015) Jure Vajs et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Ruthenium(II) p -cymene complex bearing 2,2′-dipyridylamine targets caspase 3 deficient MCF-7 breast cancer cells without disruption of antitumor immune response
- (2015) Goran N. Kaluđerović et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Modulating the Anticancer Activity of Ruthenium(II)–Arene Complexes
- (2015) Catherine M. Clavel et al. JOURNAL OF MEDICINAL CHEMISTRY
- Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure–Activity Relationship Study
- (2015) Jyoti Yellol et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, DNA binding and photocleavage, and cellular uptake of an alkyl chain-linked dinuclear ruthenium(II) complex
- (2015) Ping Liu et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Synthesis, characterization and anticancer activity of dinuclear ruthenium(ii) complexes linked by an alkyl chain
- (2015) Yan Zhang et al. NEW JOURNAL OF CHEMISTRY
- Isostructural Re(i)/99mTc(i) tricarbonyl complexes for cancer theranostics
- (2015) Patrique Nunes et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- A novel class of ruthenium-based photosensitizers effectively kills in vitro cancer cells and in vivo tumors
- (2015) Jamie Fong et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- A Family of Potent Ru(II) Photosensitizers with Enhanced DNA Intercalation: Bimodal Photokillers
- (2015) Eleftherios K. Pefkianakis et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Synthesis, characterization, crystal structure, cytotoxicity, apoptosis and cell cycle arrest of ruthenium(ii) complex [Ru(bpy)2(adpa)](PF6)2 (bpy = 2,2′-bipyridine, adpa = 4-(4-aminophenyl)diazenyl-N-(pyridin-2-ylmethylene)aniline)
- (2015) Yan Zhang et al. RSC Advances
- Organoiridium Complexes: Anticancer Agents and Catalysts
- (2014) Zhe Liu et al. ACCOUNTS OF CHEMICAL RESEARCH
- Recent Advances in Multinuclear Complexes as Potential Anticancer and DNA Binding Agents
- (2014) Kehua Wang et al. Anti-Cancer Agents in Medicinal Chemistry
- Targeting DNA damage response in cancer therapy
- (2014) Noriko Hosoya et al. CANCER SCIENCE
- Dinuclear [{(p-cym)RuCl}2(μ-phpy)](PF6)2 and heterodinuclear [(ppy)2Ir(μ-phpy)Ru(p-cym)Cl](PF6)2 complexes: synthesis, structure and anticancer activity
- (2014) Suman Kumar Tripathy et al. DALTON TRANSACTIONS
- Cisplatin in cancer therapy: Molecular mechanisms of action
- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Rhodium, Iridium, and Ruthenium Half-Sandwich Picolinamide Complexes as Anticancer Agents
- (2014) Zahra Almodares et al. INORGANIC CHEMISTRY
- Reactivity of hexanuclear ruthenium metallaprisms towards nucleotides and a DNA decamer
- (2014) Lydia E. H. Paul et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Thermodynamic Investigations of [(phen)2Ru(tatpp)Ru(phen)2]4+ Interactions with B-DNA
- (2014) Vu H. Le et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Metallomics insights into the programmed cell death induced by metal-based anticancer compounds
- (2014) Cai-Ping Tan et al. Metallomics
- Multinuclear ruthenium(ii) complexes as anticancer agents
- (2014) Anil K. Gorle et al. NEW JOURNAL OF CHEMISTRY
- Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C∧N-Chelated and Pyridine Ligands
- (2014) Zhe Liu et al. ORGANOMETALLICS
- NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application
- (2014) Robert Trondl et al. Chemical Science
- Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis
- (2013) Jessica M. Hearn et al. ACS Chemical Biology
- Predicting small molecule fluorescent probe localization in living cells using QSAR modeling. 2. Specifying probe, protocol and cell factors; selecting QSAR models; predicting entry and localization
- (2013) RW Horobin et al. BIOTECHNIC & HISTOCHEMISTRY
- Predicting small molecule fluorescent probe localization in living cells using QSAR modeling. 1. Overview and models for probes of structure, properties and function in single cells
- (2013) RW Horobin et al. BIOTECHNIC & HISTOCHEMISTRY
- A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria
- (2013) Na Jiang et al. CHEMICAL COMMUNICATIONS
- Targeting Mitochondrial DNA with a Platinum-Based Anticancer Agent
- (2013) Simon P. Wisnovsky et al. CHEMISTRY & BIOLOGY
- Bioactive iridium and rhodium complexes as therapeutic agents
- (2013) Chung-Hang Leung et al. COORDINATION CHEMISTRY REVIEWS
- Chiral ruthenium(ii) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα
- (2013) Pingyu Zhang et al. DALTON TRANSACTIONS
- Synthesis, characterization and in vitro anticancer activity of highly cytotoxic trithiolato diruthenium complexes of the type [(η6-p-MeC6H4iPr)2Ru2(μ2-SR1)2(μ2-SR2)]+ containing different thiolato bridges
- (2013) Federico Giannini et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(ii) asymmetric complexes
- (2013) Chen Qian et al. Metallomics
- Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(ii) polypyridyl complex
- (2013) Martin R. Gill et al. Chemical Science
- Ruthenium(ii) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics
- (2012) Martin R. Gill et al. CHEMICAL SOCIETY REVIEWS
- Cytotoxicity and cellular impact of dinuclear organoiridium DNA intercalators and nucleases with long rigid bridging ligands
- (2012) Mhd. Ali Nazif et al. DALTON TRANSACTIONS
- Rhodium(III) and iridium(III) complexes as anticancer agents
- (2012) Yvonne Geldmacher et al. INORGANICA CHIMICA ACTA
- Chemistry of DNA minor groove binding agents
- (2012) Gul Shahzada Khan et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid
- (2012) Vanessa Pierroz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Minimizing the damage: repair pathways keep mitochondrial DNA intact
- (2012) Lawrence Kazak et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Naphthalimide-Tagged Ruthenium–Arene Anticancer Complexes: Combining Coordination with Intercalation
- (2012) Kelly J. Kilpin et al. ORGANOMETALLICS
- Correlation Between Cellular Localization and Binding Preference to RNA, DNA, and Phospholipid Membrane for Luminescent Ruthenium(II) Complexes
- (2011) Maria Matson et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Natural product DNA major groove binders
- (2011) Paris L. Hamilton et al. NATURAL PRODUCT REPORTS
- Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
- (2011) Shankar Balasubramanian et al. NATURE REVIEWS DRUG DISCOVERY
- Coordination-Driven Self-Assembly and Anticancer Activity of Molecular Rectangles Containing Octahedral Ruthenium Metal Centers
- (2011) Vaishali Vajpayee et al. ORGANOMETALLICS
- Synthesis, Characterization and Anticancer Activity of Porphyrin-Containing Organometallic Cubes
- (2010) Nicolas P. E. Barry et al. AUSTRALIAN JOURNAL OF CHEMISTRY
- Ruthenium-based chemotherapeutics: are they ready for prime time?
- (2010) Emmanuel S. Antonarakis et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Anticancer activity of opened arene ruthenium metalla-assemblies
- (2010) Nicolas P. E. Barry et al. DALTON TRANSACTIONS
- The status of platinum anticancer drugs in the clinic and in clinical trials
- (2010) Nial J. Wheate et al. DALTON TRANSACTIONS
- Redox, Spectroscopic, and Photophysical Properties of Ru−Pt Mixed-Metal Complexes Incorporating 4,7-Diphenyl-1,10-phenanthroline as Efficient DNA Binding and Photocleaving Agents
- (2010) Samantha L. H. Higgins et al. INORGANIC CHEMISTRY
- Nuclear Permeable Ruthenium(II) β-Carboline Complexes Induce Autophagy To Antagonize Mitochondrial-Mediated Apoptosis
- (2010) Caiping Tan et al. JOURNAL OF MEDICINAL CHEMISTRY
- High-Fidelity Hydrophilic Probe for Two-Photon Fluorescence Lysosomal Imaging
- (2010) Xuhua Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP
- (2009) Xiangjun Meng et al. CANCER RESEARCH
- A Cytotoxic Ruthenium Tris(Bipyridyl) Complex that Accumulates at Plasma Membranes
- (2009) Olivier Zava et al. CHEMBIOCHEM
- Ruthenium(II)–arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity
- (2009) Sanja Grgurić-Šipka et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Anticancer activity of multinuclear arene ruthenium complexes coordinated to dendritic polypyridyl scaffolds
- (2009) Preshendren Govender et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
- A ruthenium(II) polypyridyl complex for direct imaging of DNA structure in living cells
- (2009) Martin R. Gill et al. Nature Chemistry
- Influence of the Arene Ligand, the Number and Type of Metal Centers, and the Leaving Group on thein VitroAntitumor Activity of Polynuclear Organometallic Compounds
- (2009) Maria G. Mendoza-Ferri et al. ORGANOMETALLICS
- KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients
- (2008) Christian G. Hartinger et al. CHEMISTRY & BIODIVERSITY
- Therapeutic Nanoparticles for Drug Delivery in Cancer
- (2008) K. Cho et al. CLINICAL CANCER RESEARCH
- The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways
- (2008) Soumya Chatterjee et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Luminescent Biological Probes Derived from Ruthenium(II) Estradiol Polypyridine Complexes
- (2007) Kenneth Kam-Wing Lo et al. INORGANIC CHEMISTRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started