Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium(iii) complexes

Luminescent Rhenium(I) and Iridium(III) Polypyridine Complexes as Biological Probes, Imaging Reagents, and Photocytotoxic Agents

(2015) Kenneth Kam-Wing Lo   ACCOUNTS OF CHEMICAL RESEARCH

Conferring Phosphorogenic Properties on Iridium(III)-Based Bioorthogonal Probes through Modification with a Nitrone Unit

(2015) Lawrence Cho-Cheung Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents

(2015) Yi Li et al.   BIOMATERIALS

Synergism through combination of chemotherapy and oxidative stress-induced autophagy in A549 lung cancer cells using redox-responsive nanohybrids: A new strategy for cancer therapy

(2015) Hsin-Yi Lu et al.   BIOMATERIALS

Small conjugate-based theranostic agents: an encouraging approach for cancer therapy

(2015) Rajesh Kumar et al.   CHEMICAL SOCIETY REVIEWS

Approaches to the design of catalytic metallodrugs

(2015) Joan J Soldevila-Barreda et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Cyclometalated iridium(iii) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents

(2015) Liang He et al.   Chemical Science

Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration

(2015) Wei Xiang et al.   Oncotarget

Organoiridium Complexes: Anticancer Agents and Catalysts

(2014) Zhe Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Theranostic Iridium(III) Complexes as One- and Two-Photon Phosphorescent Trackers to Monitor Autophagic Lysosomes

(2014) Liang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Potent Oxidant Anticancer Activity of Organoiridium Catalysts

(2014) Zhe Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cyclometalated Ir(iii) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy

(2014) Rui-Rong Ye et al.   CHEMICAL COMMUNICATIONS

Metal-based anticancer chemotherapeutic agents

(2014) Nafees Muhammad et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mitochondria-Immobilized pH-Sensitive Off–On Fluorescent Probe

(2014) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mitochondrial Induced and Self-Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment

(2014) Rajesh Kumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Histidine–Iridium(III) Coordination-Based Peptide Luminogenic Cyclization and Cyclo-RGD Peptides for Cancer-Cell Targeting

(2014) Xiaochuan Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A mitochondrion-targeting copper complex exhibits potent cytotoxicity against cisplatin-resistant tumor cells through multiple mechanisms of action

(2014) Wen Zhou et al.   Chemical Science

Targeting Mitochondrial DNA with a Platinum-Based Anticancer Agent

(2013) Simon P. Wisnovsky et al.   CHEMISTRY & BIOLOGY

Bioactive iridium and rhodium complexes as therapeutic agents

(2013) Chung-Hang Leung et al.   COORDINATION CHEMISTRY REVIEWS

Cyclometalated Iridium(III) Complexes for Phosphorescence Sensing of Biological Metal Ions

(2013) Youngmin You et al.   INORGANIC CHEMISTRY

Near-Infrared-Emitting Iridium(III) Complexes as Phosphorescent Dyes for Live Cell Imaging

(2013) Guoliang Zhang et al.   ORGANOMETALLICS

A Metal-Based Inhibitor of Tumor Necrosis Factor-α

(2012) Chung-Hang Leung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

The potential of organometallic complexes in medicinal chemistry

(2012) Gilles Gasser et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Next-Generation Anticancer Metallodrugs

(2012) Seiji Komeda et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A Photostable AIE Luminogen for Specific Mitochondrial Imaging and Tracking

(2012) Chris Wai Tung Leung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Organometallic Half-Sandwich Iridium Anticancer Complexes

(2011) Zhe Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phosphorescent Sensor for Biological Mobile Zinc

(2011) Youngmin You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphorescent Sensor for Robust Quantification of Copper(II) Ion

(2011) Youngmin You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells

(2011) Chunyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium Complex with Antiangiogenic Properties

(2010) Alexander Wilbuer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Advances in measuring cellular bioenergetics using extracellular flux

(2008) David A. Ferrick et al.   DRUG DISCOVERY TODAY

A Series of Red-Light-Emitting Ionic Iridium Complexes: Structures, Excited State Properties, and Application in Electroluminescent Devices

(2008) Shu-Juan Liu et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Luminescent Cyclometalated Iridium(III) Polypyridine Indole ComplexesSynthesis, Photophysics, Electrochemistry, Protein-Binding Properties, Cytotoxicity, and Cellular Uptake

(2008) Jason Shing-Yip Lau et al.   INORGANIC CHEMISTRY