Inhibition of cancer cell growth by ruthenium complexes

Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential

(2015) P.-S. Kuhn et al.   DALTON TRANSACTIONS

Lipid Nanocarriers of a Lipid-Conjugated Estrogenic Derivative Inhibit Tumor Growth and Enhance Cisplatin Activity against Triple-Negative Breast Cancer: Pharmacokinetic and Efficacy Evaluation

(2015) Terrick Andey et al.   MOLECULAR PHARMACEUTICS

Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy

(2015) Andrea Weiss et al.   Scientific Reports

Preclinical combination therapy of the investigational drug NAMI-A+ with doxorubicin for mammary cancer

(2014) Alberta Bergamo et al.   INVESTIGATIONAL NEW DRUGS

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

(2014) Suzanne Leijen et al.   INVESTIGATIONAL NEW DRUGS

Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity

(2014) Zenita Adhireksan et al.   Nature Communications

Critical role for reactive oxygen species in apoptosis induction and cell migration inhibition by diallyl trisulfide, a cancer chemopreventive component of garlic

(2013) Kumar Chandra-Kuntal et al.   BREAST CANCER RESEARCH AND TREATMENT

Exploration of the medical periodic table: towards new targets

(2013) Nicolas P. E. Barry et al.   CHEMICAL COMMUNICATIONS

A Tripodal Ruthenium–Gadolinium Metallostar as a Potential αvβ3 Integrin Specific Bimodal Imaging Contrast Agent

(2012) Peter Verwilst et al.   INORGANIC CHEMISTRY

Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity

(2012) Soledad Betanzos-Lara et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Cyclophosphamide Promotes Chronic Inflammation–Dependent Immunosuppression and Prevents Antitumor Response in Melanoma

(2012) Alexandra Sevko et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes

(2012) Soledad Betanzos-Lara et al.   ORGANOMETALLICS

Organometallic ruthenium-based antitumor compounds with novel modes of action

(2010) Wee Han Ang et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Guidelines for accurate EC50/IC50 estimation

(2010) J. L. Sebaugh   PHARMACEUTICAL STATISTICS

Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study

(2009) Frederike Lentz et al.   ANTI-CANCER DRUGS

Ruthenium(II) Arene Anticancer Complexes with Redox-Active Diamine Ligands

(2009) Tijana Bugarcic et al.   INORGANIC CHEMISTRY

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

(2009) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Caspase Mediated Enhanced Apoptotic Action of Cyclophosphamide- and Resveratrol-Treated MCF-7 Cells

(2009) Neetu Singh et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Shorter survival-times following adjuvant endocrine therapy in oestrogen- and progesterone-receptor positive breast cancer overexpressing HER2 and/or with an increased expression of vascular endothelial growth factor

(2009) B. Linderholm et al.   MEDICAL ONCOLOGY

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy

(2008) Scott J. Dylla et al.   PLoS One