Deciphering albumin-directed drug delivery by imaging

Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets

(2021) Michael P. Vincent et al.   Nature Communications

Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates

(2021) Jacob T. Martin et al.   BIOMATERIALS

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

(2021) Kevin O. Saunders et al.   NATURE

Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells

(2021) Kavya Rakhra et al.   Science Immunology

Serial intravital imaging captures dynamic and functional endothelial remodeling with single-cell resolution

(2021) Dorinne Desposito et al.   JCI Insight

Immunohistochemistry in postmortem diagnosis of acute cerebral hypoxia and ischemia

(2021) Rosario Barranco et al.   MEDICINE

Exploring the Influence of Different Albumin Binders on Molecular Imaging Probe Distribution

(2021) Carsten Höltke et al.   MOLECULAR PHARMACEUTICS

Rapid generation of potent antibodies by autonomous hypermutation in yeast

(2021) Alon Wellner et al.   Nature Chemical Biology

How Different Albumin-Binders Drive Probe Distribution of Fluorescent RGD Mimetics

(2021) Carsten Höltke et al.   Frontiers in Chemistry

nab-Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors

(2021) Andrew J. Wagner et al.   JOURNAL OF CLINICAL ONCOLOGY

Albumin Binder–Conjugated Fibroblast Activation Protein Inhibitor Radiopharmaceuticals for Cancer Therapy

(2021) Mengxin Xu et al.   JOURNAL OF NUCLEAR MEDICINE

Dynamics of intracellular neonatal Fc receptor–ligand interactions in primary macrophages using biophysical fluorescence techniques

(2021) Andreas Pannek et al.   MOLECULAR BIOLOGY OF THE CELL

X-rays-optimized delivery of radiolabeled albumin for cancer theranostics

(2020) Xuan Yi et al.   BIOMATERIALS

FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs

(2020) Maja Thim Larsen et al.   JOURNAL OF CONTROLLED RELEASE

Radiotheranostics: a roadmap for future development

(2020) Ken Herrmann et al.   LANCET ONCOLOGY

Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-Length Antibodies

(2020) Lidia Nazarova et al.   MOLECULAR CANCER THERAPEUTICS

Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy

(2020) Andreane Cartier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macropinocytosis drives T cell growth by sustaining the activation of mTORC1

(2020) John C. Charpentier et al.   Nature Communications

Vitamin D Binding Protein: A Historic Overview

(2020) Roger Bouillon et al.   Frontiers in Endocrinology

Albumin-Based Nanotheranostic Probe with Hypoxia Alleviating Potentiates Synchronous Multimodal Imaging and Phototherapy for Glioma

(2020) Zhenzhen Yang et al.   ACS Nano

Understanding the In Vivo Fate of Advanced Materials by Imaging

(2020) Ran Li et al.   ADVANCED FUNCTIONAL MATERIALS

Mechanisms of palmitic acid-conjugated antisense oligonucleotide distribution in mice

(2020) Alfred E Chappell et al.   NUCLEIC ACIDS RESEARCH

Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver

(2020) Lei Miao et al.   Nature Communications

Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines

(2020) Naveen K. Mehta et al.   Nature Biomedical Engineering

Quantitative Systems Pharmacology approaches for Immuno‐oncology: adding virtual patients to the development paradigm

(2020) Vijayalakshmi Chelliah et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Controlled loading of albumin-drug conjugates ex vivo for enhanced drug delivery and antitumor efficacy

(2020) Xinquan Liu et al.   JOURNAL OF CONTROLLED RELEASE

Physiological blood–brain transport is impaired with age by a shift in transcytosis

(2020) Andrew C. Yang et al.   NATURE

Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis

(2020) Sara Lovisa et al.   Science Signaling

3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope–specific plasma cells and humoral immunity in nonhuman primates

(2020) Sudhir Pai Kasturi et al.   Science Immunology

An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

(2020) Malin Bern et al.   Science Translational Medicine

[68Ga]ABY-028: an albumin-binding domain (ABD) protein-based imaging tracer for positron emission tomography (PET) studies of altered vascular permeability and predictions of albumin-drug conjugate transport

(2020) Emma Jussing et al.   EJNMMI Research

Analysis of SPARC and TUBB3 as predictors for prognosis in esophageal squamous cell carcinoma receiving nab-paclitaxel plus cisplatin neoadjuvant chemotherapy: a prospective study

(2019) Lei Gong et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology

(2019) Jessie L.-S. Au et al.   PHARMACOLOGICAL REVIEWS

KRAS-enhanced macropinocytosis and reduced FcRn-mediated recycling sensitize pancreatic cancer to albumin-conjugated drugs

(2019) Huiqin Liu et al.   JOURNAL OF CONTROLLED RELEASE

CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells - role in fatty acid delivery

(2019) Hira Raheel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy

(2019) Gulsah Erel-Akbaba et al.   ACS Nano

Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

(2019) Dilip K. Challa et al.   mAbs

Radiolabeled IgG Antibodies - Impact of Various Labels on Neonatal Fc Receptor Binding

(2019) Martin R. Edelmann et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

(2019) Thazha P Prakash et al.   NUCLEIC ACIDS RESEARCH

Late Gadolinium Hyperintensity of Suspected Colorectal Liver Metastases on Gadofosveset-Enhanced Magnetic Resonance Imaging: A Predictor of Benignity and a Potential Problem-Solving Tool

(2019) Helen M.C. Cheung et al.   CANADIAN ASSOCIATION OF RADIOLOGISTS JOURNAL-JOURNAL DE L ASSOCIATION CANADIENNE DES RADIOLOGISTES

FcRn mediates fast recycling of endocytosed albumin and IgG from early macropinosomes in primary macrophages

(2019) Wei Hong Toh et al.   JOURNAL OF CELL SCIENCE

Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

(2019) Stefanie R. Mullins et al.   Journal for ImmunoTherapy of Cancer

A Comparative Study on Albumin-Binding Molecules for Targeted Tumor Delivery through Covalent and Noncovalent Approach

(2019) Wooram Um et al.   BIOCONJUGATE CHEMISTRY

PET imaging of the EPR effect in tumor xenografts using small 15 nm diameter polyethylene glycols labeled with zirconium-89

(2019) Denis R Beckford Vera et al.   MOLECULAR CANCER THERAPEUTICS

Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis

(2019) Mette Mathiesen Janiurek et al.   eLife

Development of new in vitro models of lung protease activity for investigating stability of inhaled biological therapies and drug delivery systems

(2019) Arcadia Woods et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance

(2019) Spencer A. Freeman et al.   SCIENCE

Tumor targeting via EPR: Strategies to enhance patient responses

(2018) Susanne K. Golombek et al.   ADVANCED DRUG DELIVERY REVIEWS

Estimation of clinical trial success rates and related parameters

(2018) Chi Heem Wong et al.   BIOSTATISTICS

Supramolecular photosensitizers rejuvenate photodynamic therapy

(2018) Xingshu Li et al.   CHEMICAL SOCIETY REVIEWS

Evans Blue Dye: A Revisit of Its Applications in Biomedicine

(2018) Linpeng Yao et al.   Contrast Media & Molecular Imaging

The Phenomenon of Albumin-Mediated Hepatic Uptake of Organic Anion Transport Polypeptide Substrates: Prediction of the In Vivo Uptake Clearance from the In Vitro Uptake by Isolated Hepatocytes Using a Facilitated-Dissociation Model

(2018) Seiji Miyauchi et al.   DRUG METABOLISM AND DISPOSITION

Additional Clinical Value for PET/MRI in Oncology: Moving Beyond Simple Diagnosis

(2018) Kenneth A. Miles et al.   JOURNAL OF NUCLEAR MEDICINE

Safety, Pharmacokinetics and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analogue177Lu-DOTA-EB-TATE in Patients with Advanced Metastatic Neuroendocrine Tumors

(2018) Jingjing Zhang et al.   JOURNAL OF NUCLEAR MEDICINE

Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity

(2018) Junxia Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN Deficiency and AMPK Activation Promote Nutrient Scavenging and Anabolism in Prostate Cancer Cells

(2018) Seong M. Kim et al.   Cancer Discovery

Aldoxorubicin: a tumor-targeted doxorubicin conjugate for relapsed or refractory soft tissue sarcomas

(2018) Jun Gong et al.   Drug Design Development and Therapy

Evans Blue Attachment Enhances Somatostatin Receptor Subtype-2 Imaging and Radiotherapy

(2018) Rui Tian et al.   Theranostics

Response to Single Low-dose 177Lu-DOTA-EB-TATE Treatment in Patients with Advanced Neuroendocrine Neoplasm: A Prospective Pilot Study

(2018) Hao Wang et al.   Theranostics

Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines

(2018) Helen Lee et al.   Theranostics

Enhancement of peptide vaccine immunogenicity by increasing lymphatic drainage and boosting serum stability

(2018) Kelly D Moynihan et al.   Cancer Immunology Research

Gadofosveset-enhanced magnetic resonance imaging as a problem-solving tool for diagnosing colorectal liver metastases: a case report

(2018) Helen Cheung et al.   QUANTITATIVE IMAGING IN MEDICINE AND SURGERY

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Harnessing albumin as a carrier for cancer therapies

(2018) Ella N. Hoogenboezem et al.   ADVANCED DRUG DELIVERY REVIEWS

Through Scalp and Skull NIR-II Photothermal Therapy of Deep Orthotopic Brain Tumors with Precise Photoacoustic Imaging Guidance

(2018) Bing Guo et al.   ADVANCED MATERIALS

Neuropathology as a consequence of neonatal ventilation in premature growth restricted lambs

(2018) Atul Malhotra et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Single Low-Dose Injection of Evans Blue Modified PSMA-617 Radioligand Therapy Eliminates Prostate-Specific Membrane Antigen Positive Tumors

(2018) Zhantong Wang et al.   BIOCONJUGATE CHEMISTRY

Quantitative Profiling of the Lymph Node Clearance Capacity

(2018) Cristina C. Clement et al.   Scientific Reports

Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation

(2018) Miles A. Miller et al.   ACS Nano

Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin

(2018) Hye-Yeong Kim et al.   ACS Nano

Investigation on the Interaction of Dabrafenib with Human Serum Albumin Using Combined Experiment and Molecular Dynamics Simulation: Exploring the Binding Mechanism, Esterase-like Activity, and Antioxidant Activity

(2018) Zili Suo et al.   MOLECULAR PHARMACEUTICS

Design and characterization of MP0250, a tri-specific anti-HGF/anti-VEGF DARPin® drug candidate

(2017) H. Kaspar Binz et al.   mAbs

Age-associated changes in the blood-brain barrier: comparative studies in human and mouse

(2017) E. F. Goodall et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Critical role for PI3-kinase in regulating the use of proteins as an amino acid source

(2017) Wilhelm Palm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing

(2017) Samantha M. Sarett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts

(2017) Miles A. Miller et al.   Science Translational Medicine

Acylated heptapeptide binds albumin with high affinity and application as tag furnishes long-acting peptides

(2017) Alessandro Zorzi et al.   Nature Communications

Nano-palladium is a cellular catalyst for in vivo chemistry

(2017) Miles A. Miller et al.   Nature Communications

Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

(2017) Guizhi Zhu et al.   Nature Communications

Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer

(2017) Jane Cullis et al.   Cancer Immunology Research

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

Albumin Carriers for Cancer Theranostics: A Conventional Platform with New Promise

(2016) Qian Chen et al.   ADVANCED MATERIALS

Albumin-binding caspase-cleavable prodrug that is selectively activated in radiation exposed local tumor

(2016) Seung Woo Chung et al.   BIOMATERIALS

Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy

(2016) Zhibo Liu et al.   CHEMICAL SOCIETY REVIEWS

Combined gadoxetic acid and gadofosveset enhanced liver MRI for detection and characterization of liver metastases

(2016) Peter Bannas et al.   EUROPEAN RADIOLOGY

Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs

(2016) Dorthe Viuff et al.   JOURNAL OF CONTROLLED RELEASE

Prussian blue/serum albumin/indocyanine green as a multifunctional nanotheranostic agent for bimodal imaging guided laser mediated combinatorial phototherapy

(2016) Abhishek Sahu et al.   JOURNAL OF CONTROLLED RELEASE

Novel “Add-On” Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents

(2016) Haojun Chen et al.   JOURNAL OF NUCLEAR MEDICINE

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors

(2016) Shawn M Davidson et al.   NATURE MEDICINE

Multiple binding modes of ibuprofen in human serum albumin identified by absolute binding free energy calculations

(2016) Stefania Evoli et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

(2016) P. L. Stahl et al.   SCIENCE

Loss of expression of the recycling receptor, FcRn, promotes tumor cell growth by increasing albumin consumption

(2016) Rafal Swiercz et al.   Oncotarget

Current Approaches of Photothermal Therapy in Treating Cancer Metastasis with Nanotherapeutics

(2016) Lili Zou et al.   Theranostics

Advances in Therapeutic Fc Engineering – Modulation of IgG-Associated Effector Functions and Serum Half-life

(2016) Abhishek Saxena et al.   Frontiers in Immunology

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo

(2015) Anil V. Nair et al.   ACS Nano

Hydrophobic IR780 encapsulated in biodegradable human serum albumin nanoparticles for photothermal and photodynamic therapy

(2015) Chenxiao Jiang et al.   Acta Biomaterialia

Simulating the influence of plasma protein on measured receptor affinity in biochemical assays reveals the utility of Schild analysis for estimating compound affinity for plasma proteins

(2015) D Blakeley et al.   BRITISH JOURNAL OF PHARMACOLOGY

Afamin — A pleiotropic glycoprotein involved in various disease states

(2015) Hans Dieplinger et al.   CLINICA CHIMICA ACTA

SPARC Expression Did Not Predict Efficacy of nab-Paclitaxel plus Gemcitabine or Gemcitabine Alone for Metastatic Pancreatic Cancer in an Exploratory Analysis of the Phase III MPACT Trial

(2015) M. Hidalgo et al.   CLINICAL CANCER RESEARCH

Collecting Lymphatic Vessel Permeability Facilitates Adipose Tissue Inflammation and Distribution of Antigen to Lymph Node–Homing Adipose Tissue Dendritic Cells

(2015) Emma L. Kuan et al.   JOURNAL OF IMMUNOLOGY

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide

(2015) Jesper Lau et al.   JOURNAL OF MEDICINAL CHEMISTRY

Clinical Translation of an Albumin-Binding PET Radiotracer 68Ga-NEB

(2015) J. Zhang et al.   JOURNAL OF NUCLEAR MEDICINE

Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs

(2015) Derry C Roopenian et al.   mAbs

High-resolution blood-pool-contrast-enhanced MR angiography in glioblastoma: tumor-associated neovascularization as a biomarker for patient survival. A preliminary study

(2015) Josep Puig et al.   NEURORADIOLOGY

Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle

(2015) Miles A. Miller et al.   Science Translational Medicine

Vascular permeability—the essentials

(2015) Lena Claesson-Welsh   UPSALA JOURNAL OF MEDICAL SCIENCES

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

(2015) A. S. Harney et al.   Cancer Discovery

Markers for blood-brain barrier integrity: how appropriate is Evans blue in the twenty-first century and what are the alternatives?

(2015) Norman R. Saunders et al.   Frontiers in Neuroscience

Enhanced Gene Silencing through Human Serum Albumin-Mediated Delivery of Polyethylenimine-siRNA Polyplexes

(2015) Elena Nicolì et al.   PLoS One

Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy

(2014) Zonghai Sheng et al.   ACS Nano

An albumin-based theranostic nano-agent for dual-modal imaging guided photothermal therapy to inhibit lymphatic metastasis of cancer post surgery

(2014) Qian Chen et al.   BIOMATERIALS

The Proximal Tubule and Albuminuria: Really!

(2014) L. E. Dickson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Gadofosveset-based biomarker of tissue albumin concentration: Technical validation in vitro and feasibility in vivo

(2014) Owen C. Richardson et al.   MAGNETIC RESONANCE IN MEDICINE

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

A Structure-Based Model for Predicting Serum Albumin Binding

(2014) Katrina W. Lexa et al.   PLoS One

Highly Multiplexed Subcellular RNA Sequencing in Situ

(2014) J. H. Lee et al.   SCIENCE

SPARC Expression Correlates with Tumor Response to Albumin-Bound Paclitaxel in Head and Neck Cancer Patients

(2014) Neil Desai et al.   Translational Oncology

Efflux of monoclonal antibodies from rat brain by neonatal Fc receptor, FcRn

(2013) Philip R. Cooper et al.   BRAIN RESEARCH

SPARC independent drug delivery and antitumour effects ofnab-paclitaxel in genetically engineered mice

(2013) Albrecht Neesse et al.   GUT

A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity

(2013) Hong-Bo Pang et al.   JOURNAL OF CONTROLLED RELEASE

Albumin Is Recycled from the Primary Urine by Tubular Transcytosis

(2013) V. Tenten et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies

(2013) Gabriele Proetzel et al.   METHODS

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Carbamylation of Serum Albumin as a Risk Factor for Mortality in Patients with Kidney Failure

(2013) A. H. Berg et al.   Science Translational Medicine

Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface

(2013) Michael M. Schmidt et al.   STRUCTURE

Multifunctional Albumin Nanoparticles As Combination Drug Carriers for Intra-Tumoral Chemotherapy

(2013) Mingjie Cui et al.   Advanced Healthcare Materials

Albumin-binding MR blood pool contrast agent improves diagnostic performance in human brain tumour: comparison of two contrast agents for glioblastoma

(2012) Josep Puig et al.   EUROPEAN RADIOLOGY

Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson’s disease

(2012) Valerio Pisani et al.   Journal of Neuroinflammation

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

(2012) Jan Terje Andersen et al.   Nature Communications

Leukocyte rolling and adhesion both contribute to regulation of microvascular permeability to albumin via ligation of ICAM-1

(2011) Ronen Sumagin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Rational Approach To Select Small Peptide Molecular Probes Labeled with Fluorescent Cyanine Dyes for in Vivo Optical Imaging

(2011) Mikhail Y. Berezin et al.   BIOCHEMISTRY

Evaluation of drug–human serum albumin binding interactions with support vector machine aided online automated docking

(2011) Ferenc Zsila et al.   BIOINFORMATICS

Predicting human plasma protein binding of drugs using plasma protein interaction QSAR analysis (PPI-QSAR)

(2011) Haiyan Li et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Compilation of 222 drugs’ plasma protein binding data and guidance for study designs

(2011) Fengling Zhang et al.   DRUG DISCOVERY TODAY

Impact of albumin on drug delivery — New applications on the horizon

(2011) Bakheet Elsadek et al.   JOURNAL OF CONTROLLED RELEASE

Human serum albumin: From bench to bedside

(2011) Gabriella Fanali et al.   MOLECULAR ASPECTS OF MEDICINE

Vaccine adjuvant activity of 3M-052: An imidazoquinoline designed for local activity without systemic cytokine induction

(2011) Dmitri Smirnov et al.   VACCINE

Longitudinal Investigation of Permeability and Distribution of Macromolecules in Mouse Malignant Transformation Using PET

(2010) C. B. Rygh et al.   CLINICAL CANCER RESEARCH

Nanoparticles with dextran/chitosan shell and BSA/chitosan core—Doxorubicin loading and delivery

(2010) Jianing Qi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nano spray drying: A novel method for preparing protein nanoparticles for protein therapy

(2010) Sie Huey Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

(2010) Dennis A. Smith et al.   NATURE REVIEWS DRUG DISCOVERY

Investigation of the Influence of FcRn on the Distribution of IgG to the Brain

(2009) Amit Garg et al.   AAPS Journal

Expression of caveolin-1 in hepatic cells increases oxidized LDL uptake and preserves the expression of lipoprotein receptors

(2009) To Quyen Truong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Biodistribution of gadolinium-based contrast agents, including gadolinium deposition

(2009) Silvio Aime et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

In vivodetermination of collecting lymphatic vessel permeability to albumin: a role for lymphatics in exchange

(2009) Joshua P. Scallan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Renal FcRn Reclaims Albumin but Facilitates Elimination of IgG

(2009) M. Sarav et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Filamin A Regulates Caveolae Internalization and Trafficking in Endothelial Cells

(2009) Maria Sverdlov et al.   MOLECULAR BIOLOGY OF THE CELL

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

(2009) Héctor Pérez Montoyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Portable Albumin Binder from a DNA-Encoded Chemical Library

(2008) Christoph E. Dumelin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Randomized Crossover Pharmacokinetic Study of Solvent-Based Paclitaxel and nab-Paclitaxel

(2008) E. R. Gardner et al.   CLINICAL CANCER RESEARCH

Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)

(2008) Karsten Ulbrich et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Engineering of a femtomolar affinity binding protein to human serum albumin

(2008) A. Jonsson et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology

(2008) Dennis Brown et al.   TRAFFIC