Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

(2017) Michael F. Cuccarese et al.   Nature Communications

Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors

(2016) D. D. Von Hoff et al.   CLINICAL CANCER RESEARCH

Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery

(2016) Yu Matsumoto et al.   Nature Nanotechnology

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Abstract CT234: A phase I study of MM-302, a HER2-targeted PEGylated liposomal doxorubicin, in patients with HER2+ metastatic breast cancer

(2015) Patricia LoRusso et al.   CANCER RESEARCH

Clinical Translation of Nanomedicine

(2015) Yuanzeng Min et al.   CHEMICAL REVIEWS

The intra-tumoral relationship between microcirculation, interstitial fluid pressure and liposome accumulation

(2015) Shawn Stapleton et al.   JOURNAL OF CONTROLLED RELEASE

Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)

(2015) E. Geretti et al.   MOLECULAR CANCER THERAPEUTICS

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target

(2015) Janet K. Horton et al.   RADIATION RESEARCH

Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle

(2015) Miles A. Miller et al.   Science Translational Medicine

Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug

(2015) Miles A. Miller et al.   Nature Communications

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

(2015) A. S. Harney et al.   Cancer Discovery

T H 2-Polarized CD4 + T Cells and Macrophages Limit Efficacy of Radiotherapy

(2015) Stephen L. Shiao et al.   Cancer Immunology Research

Preclinical Activity of Nanoliposomal Irinotecan Is Governed by Tumor Deposition and Intratumor Prodrug Conversion

(2014) A. V. Kalra et al.   CANCER RESEARCH

Platinum Compounds for High-Resolution In Vivo Cancer Imaging

(2014) Miles A. Miller et al.   ChemMedChem

Extensible visualization and analysis for multidimensional images using Vaa3D

(2014) Hanchuan Peng et al.   Nature Protocols

Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy

(2013) Felix Klug et al.   CANCER CELL

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

Radiation-induced galectin-1 by endothelial cells: a promising molecular target for preferential drug delivery to the tumor vasculature

(2012) Meenakshi Upreti et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature

(2012) Qiong-wen Zhang et al.   PLoS One

Gadolinium Chloride Augments Tumor-Specific Imaging of Targeted Quantum Dots In Vivo

(2010) Parmeswaran Diagaradjane et al.   ACS Nano

Blockade of Tumor Necrosis Factor   Signaling in Tumor-Associated Macrophages as a Radiosensitizing Strategy

(2010) Y. Meng et al.   CANCER RESEARCH

Recruitment of Myeloid but not Endothelial Precursor Cells Facilitates Tumor Regrowth after Local Irradiation

(2010) S. V. Kozin et al.   CANCER RESEARCH

Phase II Study of Neoadjuvant Bevacizumab and Radiotherapy for Resectable Soft Tissue Sarcomas

(2010) Sam S. Yoon et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

[186Re]Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model

(2009) Anuradha Soundararajan et al.   NUCLEAR MEDICINE AND BIOLOGY

Tumor Recovery by Angiogenic Switch from Sprouting to Intussusceptive Angiogenesis after Treatment with PTK787/ZK222584 or Ionizing Radiation

(2008) Ruslan Hlushchuk et al.   AMERICAN JOURNAL OF PATHOLOGY