Root Cultures, a Boon for the Production of Valuable Compounds: A Comparative Review

Responses of in vitro cell cultures to elicitation: regulatory role of jasmonic acid and methyl jasmonate: a review

(2021) Neelofer Nabi et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

In vitro examination of anti-parasitic, anti-Alzheimer, insecticidal and cytotoxic potential of Ajuga bracteosa Wallich leaves extracts

(2021) Muhammad Imran et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Adventitious root cultures of Decalepis salicifolia for the production of 2-hydroxy-4-methoxybenzaldehyde, a vanillin isomer flavor metabolite

(2021) Vereena Rodrigues et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhancement of Celastrol compound by silver nanoparticles and acetosyringone in Celastrus paniculatus Willd. through adventitious and hairy root culture

(2021) Anil Kumar Moola et al.   JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY

Adventitious root cultures of Clitoria ternatea L. and its potential as a memory enhancer alternative

(2021) Rui Xuan Lee et al.   Plant Biotechnology Reports

Methyl jasmonate enhances ursolic, oleanolic and rosmarinic acid production and sucrose induced biomass accumulation, in hairy roots of Lepechinia caulescens

(2021) Victor M. Vergara-Martínez et al.   PeerJ

Harnessing Bacterial Endophytes for Promotion of Plant Growth and Biotechnological Applications: An Overview

(2021) Ahmed M. Eid et al.   Plants-Basel

Production of eurycomanone and polysaccharides through adventitious root culture of Eurycoma longifolia in a bioreactor

(2021) M.Z. Fan et al.   BIOCHEMICAL ENGINEERING JOURNAL

Establishment of adventitious root cultures and assessment of secoiridoid production in the Chinese medicinal plant Gentiana scabra

(2021) Ning Hao et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Enhanced production of calycosin-7-O-β-D-glucoside and astragaloside Ⅳ from adventitious root cultures of Astragalus membranaceus var. mongholicus by green leaf volatiles

(2021) Haifeng Sun et al.   INDUSTRIAL CROPS AND PRODUCTS

Drought stress-induced methyl jasmonate accumulation promotes calycosin-7-O-β-d-glucoside production in Astragalus membranaceus adventitious roots

(2021) Yichuan Feng et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Rhizogenic agrobacteria as an innovative tool for plant breeding: current achievements and limitations

(2020) Siel Desmet et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effects of 24-epibrassinolide and l-phenylalanine on growth and caffeic acid derivative production in hairy root culture of Echinacea purpurea L. Moench.

(2020) Tunhan Demirci et al.   ACTA PHYSIOLOGIAE PLANTARUM

Conventional and Molecular Techniques from Simple Breeding to Speed Breeding in Crop Plants: Recent Advances and Future Outlook

(2020) Sunny Ahmar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biotechnological Interventions for Ginsenosides Production

(2020) Saikat Gantait et al.   Biomolecules

Effect of Gibberellic Acid on Production of Biomass, Polyphenolics and Steviol Glycosides in Adventitious Root Cultures of Stevia rebaudiana (Bert.)

(2020) Ashfaq Ahmad et al.   Plants-Basel

Physical and biochemical differences in Agrobacterium rhizogenes-mediated transgenic hairy root lines of Echinacea purpurea

(2020) Tunhan Demirci et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Ginsenoside synthesis of adventitious roots in Panax ginseng is promoted by fungal suspension homogenate of Alternaria panax and regulated by several signaling molecules

(2020) Yue-Jun Hao et al.   INDUSTRIAL CROPS AND PRODUCTS

Enhanced production of anthraquinones and phenolic compounds using chitosan from the adventitious roots of Morinda coreia Buck. and Ham.

(2020) N Kannan et al.   INDUSTRIAL CROPS AND PRODUCTS

Identification of secondary metabolites in Tripterygium wilfordii hairy roots and culture optimization for enhancing wilforgine and wilforine production

(2020) Bing Zhang et al.   INDUSTRIAL CROPS AND PRODUCTS

Enhanced production of valtrate in hairy root cultures of Valeriana jatamansi Jones by methyl jasmonate, jasmonic acid and salicylic acid elicitors

(2020) Shuang ZHAO et al.   Notulae Botanicae Horti Agrobotanici Cluj-Napoca

Iron nano modulated growth and biosynthesis of steviol glycosides in Stevia rebaudiana

(2020) Mubarak Ali Khan et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Hairy Root Culture an Alternative for Bioactive Compound Production from Medicinal Plants

(2020) Arpita Roy   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Improvement of bioactive saponin accumulation in adventitious root cultures of Panax vietnamensis via culture periods and elicitation

(2019) Nguyen Thi Nhat Linh et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Effect of explant type and genotype on the accumulation of bioactive compounds in adventitious root cultures of Polygonum multiflorum

(2019) Thanh-Tam Ho et al.   PLANT CELL TISSUE AND ORGAN CULTURE

A high production of flavonoids and anthraquinones via adventitious root culture of Oplopanax elatus and evaluating antioxidant activity

(2019) L. Han et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Enhancement of saponin accumulation in adventitious root culture of Javanese ginseng (Talinum paniculatum Gaertn.) through methyl jasmonate and salicylic acid elicitation

(2019) Faizal Ahmad et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

Elicitation of withaferin-A in hairy root culture of Withania somnifera (L.) Dunal using natural polysaccharides

(2019) Chandrasekaran Thilip et al.   BIOLOGIA

Production of biomass and medicinal metabolites through adventitious roots in Ajuga bracteosa under different spectral lights

(2019) Huma Ali et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Chitosan promoting formononetin and calycosin accumulation in Astragalus membranaceus hairy root cultures via mitogen-activated protein kinase signaling cascades

(2019) Qing-Yan Gai et al.   Scientific Reports

Sustainable production of biomass and industrially important secondary metabolites in cell cultures of selfheal (Prunella vulgaris L.) elicited by silver and gold nanoparticles

(2019) Hina Fazal et al.   Artificial Cells Nanomedicine and Biotechnology

Anticancer Plants: A Review of the Active Phytochemicals, Applications in Animal Models, and Regulatory Aspects

(2019) Tariq Khan et al.   Biomolecules

Elicitor mediated adventitious root culture for the large-scale production of anthraquinones from Oldenlandia umbellata L.

(2018) S.R. Saranya Krishnan et al.   INDUSTRIAL CROPS AND PRODUCTS

Performance of a sequencing-batch membrane bioreactor (SMBR) with an automatic control strategy treating high-strength swine wastewater

(2018) Qianwen Sui et al.   JOURNAL OF HAZARDOUS MATERIALS

Impacts of hormonal elicitors and photoperiod regimes on elicitation of bioactive secondary volatiles in cell cultures of Ajuga bracteosa

(2018) Huma Ali et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Response of Plant Secondary Metabolites to Environmental Factors

(2018) et al.   MOLECULES

Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza

(2018) Xin Zhai et al.   Frontiers in Microbiology

Elicitation Enhanced the Yield of Glycyrrhizin and Antioxidant Activities in Hairy Root Cultures of Glycyrrhiza glabra L.

(2018) Mrinalini Srivastava et al.   JOURNAL OF PLANT GROWTH REGULATION

Optimization of culture medium components and culture period for production of adventitious roots of Echinacea pallida (Nutt.) Nutt

(2018) Y. Gao et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Echinacea purpurea -derived alkylamides exhibit potent anti-inflammatory effects and alleviate clinical symptoms of atopic eczema

(2017) Attila Oláh et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Antioxidant, Antidiabetic, and Antihypertensive Properties of Echinacea purpurea Flower Extract and Caffeic Acid Derivatives Using In Vitro Models

(2017) Shiow-Ying Chiou et al.   JOURNAL OF MEDICINAL FOOD

Elicitation as a tool to improve the profiles of high-value secondary metabolites and pharmacological properties of Hypericum perforatum

(2017) Preeti Shakya et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Yeast Extract Stimulates Ginsenoside Production in Hairy Root Cultures of American Ginseng Cultivated in Shake Flasks and Nutrient Sprinkle Bioreactors

(2017) Ewa Kochan et al.   MOLECULES

Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

(2017) Tasiu Isah et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Metabolite profiling of the undifferentiated cultured cells and differentiated leaf tissues of Centella asiatica

(2017) Efficient N. Ncube et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Adventitious root culture of Polygonum multiflorum for phenolic compounds and its pilot-scale production in 500 L-tank

(2017) Thanh-Tam Ho et al.   PLANT CELL TISSUE AND ORGAN CULTURE

A MDR transporter contributes to the different extracellular production of sesquiterpene pyridine alkaloids between adventitious root and hairy root liquid cultures of Tripterygium wilfordii Hook.f.

(2017) Guo-peng Miao et al.   PLANT MOLECULAR BIOLOGY

Chitosan elicitation and sequential Diaion® HP-20 addition a powerful approach for enhanced plumbagin production in Plumbago indica root cultures

(2017) Amit Jaisi et al.   PROCESS BIOCHEMISTRY

Withania somnifera: Advances and Implementation of Molecular and Tissue Culture Techniques to Enhance Its Application

(2017) Vibha Pandey et al.   Frontiers in Plant Science

The Biphasic Root Growth Response to Abscisic Acid in Arabidopsis Involves Interaction with Ethylene and Auxin Signalling Pathways

(2017) Xiaoqing Li et al.   Frontiers in Plant Science

Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic

(2017) Ping Liu et al.   Aging and Disease

Pathogenic fungal elicitors enhance ginsenoside biosynthesis of adventitious roots in Panax quinquefolius during bioreactor culture

(2016) Yao Yu et al.   INDUSTRIAL CROPS AND PRODUCTS

Meeting the challenge of stevioside production in the hairy roots of Stevia rebaudiana by probing the underlying process

(2016) Harshita Pandey et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Conservation and sustainable use of medicinal plants: problems, progress, and prospects

(2016) Shi-Lin Chen et al.   Chinese Medicine

Establishment of in vitro fast-growing normal root culture of Vernonia amygdalina - a potent African medicinal plant

(2016) M Khalafalla M et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

Pharmacologic overview of Withania somnifera, the Indian Ginseng

(2015) Nawab John Dar et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanistic Studies on the Use ofPolygonum multiflorumfor the Treatment of Hair Graying

(2015) Ming-Nuan Han et al.   Biomed Research International

Effect of methyl jasmonate and silver nanoparticles on production of secondary metabolites by Calendula officinalis L (Asteraceae)

(2015) F Ghanati et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Ca2+signalling in plant immune response: from pattern recognition receptors to Ca2+decoding mechanisms

(2014) Heike Seybold et al.   NEW PHYTOLOGIST

Optimal inductive and cultural conditions of Polygonum multiflorum transgenic hairy roots mediated with Agrobacterium rhizogenes R1601 and an analysis of their anthraquinone constituents

(2014) Chuanyan Yan et al.   Pharmacognosy Magazine

Tools for biotechnological production of useful phytochemicals from adventitious root cultures

(2014) Hosakatte Niranjana Murthy et al.   PHYTOCHEMISTRY REVIEWS

Enhancement strategies of bioactive compound production in adventitious root cultures of Eleutherococcus koreanum Nakai subjected to methyl jasmonate and salicylic acid elicitation through airlift bioreactors

(2014) Eun Jung Lee et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Enhanced Resveratrol Production in Vitis vinifera Cell Suspension Cultures by Heavy Metals Without Loss of Cell Viability

(2013) Zhenzhen Cai et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Purification, antioxidant activity and antiglycation of polysaccharides from Polygonum multiflorum Thunb

(2013) Lishuang Lv et al.   CARBOHYDRATE POLYMERS

Stimulation of Artemisinin Production in Artemisia annua Hairy Roots by Ag-SiO2 Core-shell Nanoparticles

(2013) Ben Zhang et al.   Current Nanoscience

Increased production of withanolide A, withanone, and withaferin A in hairy root cultures of Withania somnifera (L.) Dunal elicited with methyl jasmonate and salicylic acid

(2013) Ganeshan Sivanandhan et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Enhancement of Anti-Inflammatory Activity of Aloe vera Adventitious Root Extracts through the Alteration of Primary and Secondary Metabolites via Salicylic Acid Elicitation

(2013) Yun Sun Lee et al.   PLoS One

Production of anthraquinones, phenolic compounds and biological activities from hairy root cultures of Polygonum multiflorum Thunb.

(2013) Muthu Thiruvengadam et al.   PROTOPLASMA

Optimization of Elicitation Conditions with Methyl Jasmonate and Salicylic Acid to Improve the Productivity of Withanolides in the Adventitious Root Culture of Withania somnifera (L.) Dunal

(2012) Ganeshan Sivanandhan et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Chitosan enhances withanolides production in adventitious root cultures of Withania somnifera (L.) Dunal

(2012) G. Sivanandhan et al.   INDUSTRIAL CROPS AND PRODUCTS

Carbon sources and medium pH affects the growth ofWithania somnifera(L.) Dunal adventitious roots and withanolide A production

(2012) H. N. Murthy et al.   NATURAL PRODUCT RESEARCH

Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor

(2011) Md. Abdullahil Baque et al.   BIOTECHNOLOGY ADVANCES

Synthesis of withanolide A depends on carbon source and medium pH in hairy root cultures of Withania somnifera

(2011) N. Praveen et al.   INDUSTRIAL CROPS AND PRODUCTS

Production of withanolide-A from adventitious root cultures of Withania somnifera

(2010) N. Praveen et al.   ACTA PHYSIOLOGIAE PLANTARUM

Stilbene Glucoside from Polygonum multiflorum Thunb.: A Novel Natural Inhibitor of Advanced Glycation End Product Formation by Trapping of Methylglyoxal

(2010) Lishuang Lv et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Growth, secondary metabolite production and antioxidant enzyme response of Morinda citrifolia adventitious root as affected by auxin and cytokinin

(2010) Md. Abdullahil Baque et al.   Plant Biotechnology Reports

Bioprocessing of plant cell cultures for mass production of targeted compounds

(2009) Milen I. Georgiev et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Application of an airlift bioreactor system for the production of adventitious root biomass and caffeic acid derivatives of Echinacea purpurea

(2009) Jin-A Jeong et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Supplemental ultraviolet-B induced changes in essential oil composition and total phenolics of Acorus calamus L. (sweet flag)

(2009) Rima Kumari et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Effect of exogenous salicylic acid under changing environment: A review

(2009) Qaiser Hayat et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

(2009) Mohammad Mirjalili et al.   MOLECULES

Establishment of adventitious root co-culture of Ginseng and Echinacea for the production of secondary metabolites

(2008) Chun-Hua Wu et al.   ACTA PHYSIOLOGIAE PLANTARUM

Inoculum size and auxin concentration influence the growth of adventitious roots and accumulation of ginsenosides in suspension cultures of ginseng (Panax ginseng C.A. Meyer)

(2008) C. S. Jeong et al.   ACTA PHYSIOLOGIAE PLANTARUM

Elicitor-induced transcription factors for metabolic reprogramming of secondary metabolism in Medicago truncatula

(2008) Marina A Naoumkina et al.   BMC PLANT BIOLOGY

Establishment ofWithania somniferaHairy Root Cultures for the Production of Withanolide A

(2008) Hosakatte N. Murthy et al.   Journal of Integrative Plant Biology

Transcriptional response of the terpenoid indole alkaloid pathway to the overexpression of ORCA3 along with jasmonic acid elicitation of Catharanthus roseus hairy roots over time

(2008) Christie A.M. Peebles et al.   METABOLIC ENGINEERING

Withania somnifera: An Indian ginseng

(2007) S.K. Kulkarni et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY