Bacterial vaginosis and health-associated bacteria modulate the immunometabolic landscape in 3D model of human cervix

Biogenic Amines Increase the Odds of Bacterial Vaginosis and Affect the Growth and Lactic Acid Production by Vaginal Lactobacillus spp.

(2021) Joanna-Lynn C. Borgogna et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Atopobium vaginae and Prevotella bivia Are Able to Incorporate and Influence Gene Expression in a Pre-Formed Gardnerella vaginalis Biofilm

(2021) Joana Castro et al.   Pathogens

Veillonellaceae family members uniquely alter the cervical metabolic microenvironment in a human three-dimensional epithelial model

(2021) Mary E. Salliss et al.   npj Biofilms and Microbiomes

The microbiome and gynaecological cancer development, prevention and therapy

(2020) Paweł Łaniewski et al.   Nature Reviews Urology

Neisseria gonorrhoeae Blocks Epithelial Exfoliation by Nitric-Oxide-Mediated Metabolic Cross Talk to Promote Colonization in Mice

(2020) Petra Muenzner et al.   Cell Host & Microbe

Identification of a cytopathogenic toxin from Sneathia amnii

(2020) Gabriella L. Gentile et al.   JOURNAL OF BACTERIOLOGY

A Narrative Review of Current Challenges in the Diagnosis and Management of Bacterial Vaginosis

(2020) Christina A. Muzny et al.   SEXUALLY TRANSMITTED DISEASES

Prevalence of Mycoplasma genitalium infection in women with bacterial vaginosis

(2020) Melinda B. Nye et al.   BMC Womens Health

Members of Prevotella Genus Distinctively Modulate Innate Immune and Barrier Functions in a Human Three-Dimensional Endometrial Epithelial Cell Model

(2020) Zehra Esra Ilhan et al.   JOURNAL OF INFECTIOUS DISEASES

Glycan cross-feeding supports mutualism between Fusobacterium and the vaginal microbiota

(2020) Kavita Agarwal et al.   PLOS BIOLOGY

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

(2020) Valerie P. O'Brien et al.   Jove-Journal of Visualized Experiments

Amylases in the Human Vagina

(2020) Kenetta L. Nunn et al.   mSphere

Unveiling the role of Gardnerella vaginalis in polymicrobial Bacterial Vaginosis biofilms: the impact of other vaginal pathogens living as neighbors

(2019) Joana Castro et al.   ISME Journal

High Global Burden and Costs of Bacterial Vaginosis

(2019) Kathryn Peebles et al.   SEXUALLY TRANSMITTED DISEASES

Comparative genomics of human Lactobacillus crispatus isolates reveals genes for glycosylation and glycogen degradation: implications for in vivo dominance of the vaginal microbiota

(2019) Charlotte van der Veer et al.   Microbiome

Antimicrobial and inflammatory properties of South African clinical Lactobacillus isolates and vaginal probiotics

(2019) Emily Chetwin et al.   Scientific Reports

Cervicovaginal microbiota and local immune response modulate the risk of spontaneous preterm delivery

(2019) Michal A. Elovitz et al.   Nature Communications

Gardnerella vaginalis and Prevotella bivia Trigger Distinct and Overlapping Phenotypes in a Mouse Model of Bacterial Vaginosis

(2019) Nicole M Gilbert et al.   JOURNAL OF INFECTIOUS DISEASES

Interaction of Gardnerella vaginalis and Vaginolysin with the Apical versus Basolateral Face of a Three-Dimensional Model of Vaginal Epithelium

(2019) Erin M. Garcia et al.   INFECTION AND IMMUNITY

The vaginal microbiome and preterm birth

(2019) Jennifer M. Fettweis et al.   NATURE MEDICINE

Deciphering the complex interplay between microbiota, HPV, inflammation and cancer through cervicovaginal metabolic profiling

(2019) Zehra Esra Ilhan et al.   EBioMedicine

Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection

(2019) Smritee Dabee et al.   PLoS One

Interleukin-36γ Is Elevated in Cervicovaginal Epithelial Cells in Women With Bacterial Vaginosis and In Vitro After Infection With Microbes Associated With Bacterial Vaginosis

(2019) Jameson K Gardner et al.   JOURNAL OF INFECTIOUS DISEASES

Alterations in Blood Chemistry Levels Associated With Nipah Virus Disease in the Syrian Hamster Model

(2019) Sarah C Genzer et al.   JOURNAL OF INFECTIOUS DISEASES

Host–vaginal microbiota interactions in the pathogenesis of bacterial vaginosis

(2019) Christina A. Muzny et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Novel bacterial vaginosis-associated organisms mediate the relationship between vaginal douching and pelvic inflammatory disease

(2019) Tamala Gondwe et al.   SEXUALLY TRANSMITTED INFECTIONS

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

(2018) Richard G. Brown et al.   BMC Medicine

Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term

(2018) Sophia M. R. Lannon et al.   Journal of Maternal-Fetal & Neonatal Medicine

Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer

(2018) Jie Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory cytokine biomarkers of asymptomatic sexually transmitted infections and vaginal dysbiosis: a multicentre validation study

(2018) Lindi Masson et al.   SEXUALLY TRANSMITTED INFECTIONS

Women and Their Microbes: The Unexpected Friendship

(2018) Jessica A. Younes et al.   TRENDS IN MICROBIOLOGY

Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women

(2018) Paweł Łaniewski et al.   Scientific Reports

Treatment of bacterial vaginosis to prevent preterm birth

(2018) Mark A Klebanoff et al.   LANCET

Distinct Effects of the Cervicovaginal Microbiota and Herpes Simplex Type 2 Infection on Female Genital Tract Immunology

(2017) B. Shannon et al.   JOURNAL OF INFECTIOUS DISEASES

Comparative transcriptomic analysis of Gardnerella vaginalis biofilms vs. planktonic cultures using RNA-seq

(2017) Joana Castro et al.   npj Biofilms and Microbiomes

Bacterial communities found in placental tissues are associated with severe chorioamnionitis and adverse birth outcomes

(2017) Ronan M. Doyle et al.   PLoS One

The Human Microbiome during Bacterial Vaginosis

(2016) Andrew B. Onderdonk et al.   CLINICAL MICROBIOLOGY REVIEWS

New Systems for Studying Intercellular Interactions in Bacterial Vaginosis

(2016) Melissa M. Herbst-Kralovetz et al.   JOURNAL OF INFECTIOUS DISEASES

The Vaginal Microbiome: Current Understanding and Future Directions

(2016) David H. Martin et al.   JOURNAL OF INFECTIOUS DISEASES

Desialylation ofNeisseria gonorrhoeaeLipooligosaccharide by Cervicovaginal Microbiome Sialidases: The Potential for Enhancing Infectivity in Men

(2016) Margaret R. Ketterer et al.   JOURNAL OF INFECTIOUS DISEASES

Comparison of Lactobacillus crispatus isolates from Lactobacillus-dominated vaginal microbiomes with isolates from microbiomes containing bacterial vaginosis-associated bacteria

(2016) Abdallah A. Abdelmaksoud et al.   MICROBIOLOGY-SGM

Genital inflammation, immune activation and risk of sexual HIV acquisition

(2016) Jo-Ann S. Passmore et al.   Current Opinion in HIV and AIDS

Potential contribution of the uterine microbiome in the development of endometrial cancer

(2016) Marina R. S. Walther-António et al.   Genome Medicine

Arginine- and Polyamine-Induced Lactic Acid Resistance in Neisseria gonorrhoeae

(2016) Zheng Gong et al.   PLoS One

Glycogen Levels in Undiluted Genital Fluid and Their Relationship to Vaginal pH, Estrogen, and Progesterone

(2016) Paria Mirmonsef et al.   PLoS One

Colonization of the upper genital tract by vaginal bacterial species in nonpregnant women

(2015) Caroline M. Mitchell et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Vaginal microbiome and metabolome highlight specific signatures of bacterial vaginosis

(2015) B. Vitali et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract

(2015) Melis N. Anahtar et al.   IMMUNITY

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Metabolic Signatures of Bacterial Vaginosis

(2015) Sujatha Srinivasan et al.   mBio

Vaginal biogenic amines: biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis?

(2015) Tiffanie M. Nelson et al.   Frontiers in Physiology

Persistent microbial dysbiosis in preterm premature rupture of membranes from onset until delivery

(2015) Elizabeth A. Baldwin et al.   PeerJ

Bacterial Vaginosis and the Cervicovaginal Immune Response

(2014) Caroline Mitchell et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis

(2014) Teija Ojala et al.   BMC GENOMICS

MMP-9 expression increases according to the grade of squamous intraepithelial lesion in cervical smears

(2014) Erika R. Matheus et al.   DIAGNOSTIC CYTOPATHOLOGY

Human α-amylase Present in Lower-Genital-Tract Mucosal Fluid Processes Glycogen to Support Vaginal Colonization by Lactobacillus

(2014) Gregory T. Spear et al.   JOURNAL OF INFECTIOUS DISEASES

Bacteria in the Vaginal Microbiome Alter the Innate Immune Response and Barrier Properties of the Human Vaginal Epithelia in a Species-Specific Manner

(2014) Sylvie Y. Doerflinger et al.   JOURNAL OF INFECTIOUS DISEASES

Early Pregnancy Changes in Bacterial Vaginosis-Associated Bacteria and Preterm Delivery

(2014) Deborah B. Nelson et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Bacterial Vaginosis and the Risk of Trichomonas vaginalis Acquisition Among HIV-1–Negative Women

(2014) Jennifer E. Balkus et al.   SEXUALLY TRANSMITTED DISEASES

Risks associated with bacterial vaginosis in infertility patients: a systematic review and meta-analysis

(2013) N. van Oostrum et al.   HUMAN REPRODUCTION

Degradation, Foraging, and Depletion of Mucus Sialoglycans by the Vagina-adaptedActinobacterium Gardnerella vaginalis

(2013) Warren G. Lewis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycoplasma genitalium Infection Activates Cellular Host Defense and Inflammation Pathways in a 3-Dimensional Human Endocervical Epithelial Cell Model

(2013) Chris L. McGowin et al.   JOURNAL OF INFECTIOUS DISEASES

'Leptotrichia amnionii', a newly reported cause of early onset neonatal meningitis

(2013) V. Decroix et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clinical Features of Bacterial Vaginosis in a Murine Model of Vaginal Infection with Gardnerella vaginalis

(2013) Nicole M. Gilbert et al.   PLoS One

Association of the Vaginal Microbiota with Human Papillomavirus Infection in a Korean Twin Cohort

(2013) Jung Eun Lee et al.   PLoS One

Bacterial Vaginosis–Associated Bacteria in Men

(2013) Lisa E. Manhart et al.   SEXUALLY TRANSMITTED DISEASES

Does Bacterial Vaginosis Cause Pelvic Inflammatory Disease?

(2013) Brandie DePaoli Taylor et al.   SEXUALLY TRANSMITTED DISEASES

Influence of Vaginal Bacteria and D- and L-Lactic Acid Isomers on Vaginal Extracellular Matrix Metalloproteinase Inducer: Implications for Protection against Upper Genital Tract Infections

(2013) S. S. Witkin et al.   mBio

Daily temporal dynamics of vaginal microbiota before, during and after episodes of bacterial vaginosis

(2013) Jacques Ravel et al.   Microbiome

Recent research on 3-phenyllactic acid, a broad-spectrum antimicrobial compound

(2012) Wanmeng Mu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Microbial Products Alter the Expression of Membrane-Associated Mucin and Antimicrobial Peptides in a Three-Dimensional Human Endocervical Epithelial Cell Model1

(2012) Andrea L. Radtke et al.   BIOLOGY OF REPRODUCTION

First Report of Spontaneous Intrapartum Atopobium vaginae Bacteremia

(2012) J. F. W. Chan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Commensal Bacteria Modulate Innate Immune Responses of Vaginal Epithelial Cell Multilayer Cultures

(2012) William A. Rose et al.   PLoS One

Bacterial Communities in Women with Bacterial Vaginosis: High Resolution Phylogenetic Analyses Reveal Relationships of Microbiota to Clinical Criteria

(2012) Sujatha Srinivasan et al.   PLoS One

Identification and Characterization of Bacterial Vaginosis-Associated Pathogens Using a Comprehensive Cervical-Vaginal Epithelial Coculture Assay

(2012) Colleen R. Eade et al.   PLoS One

Bacterial Vaginosis Associated with Increased Risk of Female-to-Male HIV-1 Transmission: A Prospective Cohort Analysis among African Couples

(2012) Craig R. Cohen et al.   PLOS MEDICINE

Bacterial Vaginosis, Gonorrhea, and Chlamydial Infection Among Women Attending a Sexually Transmitted Disease Clinic: A Longitudinal Analysis of Possible Causal Links

(2011) Maria F. Gallo et al.   ANNALS OF EPIDEMIOLOGY

Bacterial vaginosis is associated with uterine cervical human papillomavirus infection: a meta-analysis

(2011) Evy Gillet et al.   BMC INFECTIOUS DISEASES

Cellular expression of monocarboxylate transporters in the female reproductive organ of mice: implications for the genital lactate shuttle

(2011) Takuya Kuchiiwa et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Bacterial Vaginosis and Risk for Trichomonas vaginalis Infection: A Longitudinal Analysis

(2011) Sujit D. Rathod et al.   SEXUALLY TRANSMITTED DISEASES

Polyamines Can Increase Resistance of Neisseria gonorrhoeae to Mediators of the Innate Human Host Defense

(2010) M. Goytia et al.   INFECTION AND IMMUNITY

Neisseria gonorrhoeae Survival during Primary Human Cervical Epithelial Cell Infection Requires Nitric Oxide and Is Augmented by Progesterone

(2010) J. L. Edwards   INFECTION AND IMMUNITY

Bacterial Vaginosis Assessed by Gram Stain and Diminished Colonization Resistance to Incident Gonococcal, Chlamydial, and Trichomonal Genital Infection

(2010) Rebecca M. Brotman et al.   JOURNAL OF INFECTIOUS DISEASES

Organotypic 3D cell culture models: using the rotating wall vessel to study host–pathogen interactions

(2010) Jennifer Barrila et al.   NATURE REVIEWS MICROBIOLOGY

Keratins in health and cancer: more than mere epithelial cell markers

(2010) V Karantza   ONCOGENE

Vaginal microbiome of reproductive-age women

(2010) J. Ravel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix metalloproteinases in the cervical mucus plug in relation to gestational age, plug compartment, and preterm labor

(2010) Naja Becher et al.   Reproductive Biology and Endocrinology

In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosis

(2009) E. De Backer et al.   CLINICAL MICROBIOLOGY AND INFECTION

High Vaginal Concentrations of Atopobium vaginae and Gardnerella vaginalis in Women Undergoing Preterm Labor

(2009) Jean Pierre Menard et al.   OBSTETRICS AND GYNECOLOGY

A prospective study of risk factors for herpes simplex virus type 2 acquisition among high-risk HIV-1 seronegative women in Kenya

(2009) V Chohan et al.   SEXUALLY TRANSMITTED INFECTIONS

ORIGINAL ARTICLE: Quantification and Comparison of Toll-Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract Epithelia

(2008) Melissa M. Herbst-Kralovetz et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Uncultivated Bacteria as Etiologic Agents of Intra-Amniotic Inflammation Leading to Preterm Birth

(2008) Y. W. Han et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Mucins in the mucosal barrier to infection

(2008) S K Linden et al.   Mucosal Immunology

An adherent Gardnerella vaginalis biofilm persists on the vaginal epithelium after standard therapy with oral metronidazole

(2007) Alexander Swidsinski et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY