Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity

Hv1 proton channels differentially regulate the pH of neutrophil and macrophage phagosomes by sustaining the production of phagosomal ROS that inhibit the delivery of vacuolar ATPases

(2014) Antoun El Chemaly et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A model of lysosomal pH regulation

(2013) Yoichi Ishida et al.   JOURNAL OF GENERAL PHYSIOLOGY

Measuring Myeloperoxidase Activity in Biological Samples

(2013) Benjamin Pulli et al.   PLoS One

Chloride in Vesicular Trafficking and Function

(2012) Tobias Stauber et al.   Annual Review of Physiology

Chronic Granulomatous Disease

(2012) Steven M. Holland   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Defective tumor necrosis factor release from Crohnʼs disease macrophages in response to toll-like receptor activation: Relationship to phenotype and genome-wide association susceptibility loci

(2012) Gavin W. Sewell et al.   INFLAMMATORY BOWEL DISEASES

Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification

(2012) Lele Jiang et al.   JOURNAL OF CELL SCIENCE

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

(2012) S. J. Klebanoff et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cathepsin G and Neutrophil Elastase Play Critical and Nonredundant Roles in Lung-Protective Immunity against Streptococcus pneumoniae in Mice

(2011) Ines Hahn et al.   INFECTION AND IMMUNITY

CO Binding and Ligand Discrimination in Human Myeloperoxidase

(2010) Emma J. Murphy et al.   BIOCHEMISTRY

CFTR-mediated halide transport in phagosomes of human neutrophils

(2010) Richard G. Painter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Voltage-gated proton channel is expressed on phagosomes

(2009) Yoshifumi Okochi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

(2009) Antoun El Chemaly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

(2009) I. S. Ramsey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

(2009) D. Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into the ClC-4 Transport Mechanism from Studies of Zn2+ Inhibition

(2008) Jeremiah D. Osteen et al.   BIOPHYSICAL JOURNAL

Central mechanisms of osmosensation and systemic osmoregulation

(2008) Charles W. Bourque   NATURE REVIEWS NEUROSCIENCE

Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

(2007) Brice Korkmaz et al.   BIOCHIMIE