NLRP3 inflammasome activation and interleukin-1β release in macrophages require calcium but are independent of calcium-activated NADPH oxidases

The Pseudomonas Toxin Pyocyanin Inhibits the Dual Oxidase-Based Antimicrobial System as It Imposes Oxidative Stress on Airway Epithelial Cells

(2014) B. Rada et al.   JOURNAL OF IMMUNOLOGY

Release of Cystic Fibrosis Airway Inflammatory Markers from Pseudomonas aeruginosa-Stimulated Human Neutrophils Involves NADPH Oxidase-Dependent Extracellular DNA Trap Formation

(2014) D.-g. Yoo et al.   JOURNAL OF IMMUNOLOGY

Calcium Flashes Orchestrate the Wound Inflammatory Response through DUOX Activation and Hydrogen Peroxide Release

(2013) William Razzell et al.   CURRENT BIOLOGY

ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

(2013) Derek Sham et al.   PLoS One

Pyocyanin-Enhanced Neutrophil Extracellular Trap Formation Requires the NADPH Oxidase

(2013) Balázs Rada et al.   PLoS One

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

(2012) Geun-Shik Lee et al.   NATURE

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond

(2011) Cristina Conforti-Andreoni et al.   Cellular & Molecular Immunology

Molecular mechanisms of inflammasome activation during microbial infections

(2011) Petr Broz et al.   IMMUNOLOGICAL REVIEWS

Regulation of intracellular Ca2+ by reactive oxygen species in osteoblasts treated with antimycin A

(2011) Eun Mi Choi   JOURNAL OF APPLIED TOXICOLOGY

The Rate of Interleukin-1β Secretion in Different Myeloid Cells Varies with the Extent of Redox Response to Toll-like Receptor Triggering

(2011) Sonia Carta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Interplay between redox status and inflammasome activation

(2011) Anna Rubartelli et al.   TRENDS IN IMMUNOLOGY

Innate Immune Recognition of Francisella Tularensis: Activation of Type-I Interferons and the Inflammasome

(2011) Jonathan Wiley Jones et al.   Frontiers in Microbiology

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

(2010) F. Meissner et al.   BLOOD

Human NLRP3 inflammasome activation is Nox1-4 independent

(2010) R. van Bruggen et al.   BLOOD

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Calcium-activated K+ channel (KCa3.1) activity during Ca2+ store depletion and store-operated Ca2+ entry in human macrophages

(2010) Ya-dong Gao et al.   CELL CALCIUM

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

(2010) Rinke Stienstra et al.   Cell Metabolism

Inflammasomes: current understanding and open questions

(2010) Franz Bauernfeind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

(2010) Marije Oosting et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Urothelial cells produce hydrogen peroxide through the activation of Duox1

(2010) Ágnes Donkó et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interleukin-1β activation during acute joint inflammation: A limited role for the NLRP3 inflammasome in vivo

(2010) Leo A.B. Joosten et al.   JOINT BONE SPINE

The Role of Potassium in Inflammasome Activation by Bacteria

(2010) Cecilia S. Lindestam Arlehamn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanism of NLRP3 Inflammasome Activation

(2010) Chengcheng Jin et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells

(2010) Cristina Conforti-Andreoni et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Reactive oxygen species-independent activation of the IL-1  inflammasome in cells from patients with chronic granulomatous disease

(2010) F. L. van de Veerdonk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1  secretion

(2010) S. Tassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

(2010) J. Kwon et al.   Science Signaling

ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli

(2009) Agnes W. Boots et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

The need to identify myeloid dendritic cell progenitors in human blood

(2009) Alessandra Mortellaro et al.   TRENDS IN IMMUNOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE