APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes
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Title
APOE2, E3, and E4 differentially modulate cellular homeostasis, cholesterol metabolism, and inflammatory response in isogenic iPSC-derived astrocytes
Authors
Keywords
iPSCs, astrocytes, isogenic, APOE, cholesterol, proteomics, lipid metabolism, inflammation, homeostasis, Aβ, Alzheimer disease
Journal
Stem Cell Reports
Volume 17, Issue 1, Pages 110-126
Publisher
Elsevier BV
Online
2021-12-16
DOI
10.1016/j.stemcr.2021.11.007
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