Cell-specific production, secretion, and function of apolipoprotein E

ApoE and Lipid Homeostasis in Alzheimer’s Disease: Introduction to the Thematic Review Series

(2017) Ta-Yuan Chang et al.   JOURNAL OF LIPID RESEARCH

Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III

(2017) Raimund Pechlaner et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Differential action of glucocorticoids on apolipoprotein E gene expression in macrophages and hepatocytes

(2017) Violeta Georgeta Trusca et al.   PLoS One

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders

(2016) Robert W. Mahley   JOURNAL OF MOLECULAR MEDICINE-JMM

Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease

(2015) Liv Tybjærg Nordestgaard et al.   Alzheimers & Dementia

Krüppel-like factor 4 synergizes with CREB to increase the activity of apolipoprotein E gene promoter in macrophages

(2015) Simona Stavri et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Promoting macrophage survival delays progression of pre-existing atherosclerotic lesions through macrophage-derived apoE

(2015) Laura Bouchareychas et al.   CARDIOVASCULAR RESEARCH

Apolipoprotein E Enhances MicroRNA-146a in Monocytes and Macrophages to Suppress Nuclear Factor- B-Driven Inflammation and Atherosclerosis

(2015) K. Li et al.   CIRCULATION RESEARCH

Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes

(2015) Dorothee Lasrich et al.   EXPERIMENTAL CELL RESEARCH

Stabilization of intracellular trafficking and metabolism of amyloid β-protein precursor and Alcadein β by apolipoprotein E

(2015) Ayano Kimura et al.   FEBS LETTERS

Tissue-Specific Glycosylation at the Glycopeptide Level

(2015) Katalin F. Medzihradszky et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetic variants modify the effect of age onAPOEmethylation in the Genetics of Lipid Lowering Drugs and Diet Network study

(2014) Yiyi Ma et al.   AGING CELL

Astrocyte׳s endogenous apoE generates HDL-like lipoproteins using previously synthesized cholesterol through interaction with ABCA1

(2014) Jin-ichi Ito et al.   BRAIN RESEARCH

Selective suppression of adipose tissue apoE expression impacts systemic metabolic phenotype and adipose tissue inflammation

(2014) Zhi H. Huang et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein E synthesized by adipocyte and apolipoprotein E carried on lipoproteins modulate adipocyte triglyceride content

(2014) Yan-hong Li et al.   Lipids in Health and Disease

Pharmacological Inhibition of Dynamin II Reduces Constitutive Protein Secretion from Primary Human Macrophages

(2014) Maaike Kockx et al.   PLoS One

Phenotypic Polarization of Macrophages in Atherosclerosis

(2013) Norbert Leitinger et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protein Kinase C Controls Vesicular Transport and Secretion of Apolipoprotein E from Primary Human Macrophages

(2013) Denuja Karunakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ApoE Production in Human Monocytes and Its Regulation by Inflammatory Cytokines

(2013) Sten Braesch-Andersen et al.   PLoS One

Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt

(2012) Maaike Kockx et al.   BIOCHEMICAL JOURNAL

Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis

(2012) Nora Pencheva et al.   CELL

ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice

(2012) Zhi H. Huang et al.   JOURNAL OF LIPID RESEARCH

LC–MS/MS Characterization of O-Glycosylation Sites and Glycan Structures of Human Cerebrospinal Fluid Glycoproteins

(2012) Adnan Halim et al.   JOURNAL OF PROTEOME RESEARCH

Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages

(2011) Daniel Baitsch et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ApoE Suppresses Atherosclerosis by Reducing Lipid Accumulation in Circulating Monocytes and the Expression of Inflammatory Molecules on Monocytes and Vascular Endothelium

(2011) Nathalie Gaudreault et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

(2011) Andrew J. Murphy et al.   JOURNAL OF CLINICAL INVESTIGATION

An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia

(2011) Jianjia Fan et al.   JOURNAL OF LIPID RESEARCH

Adipose tissue depot-specific differences in adipocyte apolipoprotein E expression

(2011) Zhi H. Huang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Cellular Source of Apolipoprotein E4 Determines Neuronal Susceptibility to Excitotoxic Injury in Transgenic Mice

(2010) Manuel Buttini et al.   AMERICAN JOURNAL OF PATHOLOGY

Precision Mapping of an In Vivo N-Glycoproteome Reveals Rigid Topological and Sequence Constraints

(2010) Dorota F. Zielinska et al.   CELL

A Macrophage Sterol-Responsive Network Linked to Atherogenesis

(2010) Lev Becker et al.   Cell Metabolism

Endogenous adipocyte apolipoprotein E is colocalized with caveolin at the adipocyte plasma membrane

(2010) Lili Yue et al.   JOURNAL OF LIPID RESEARCH

Altered apolipoprotein E glycosylation is associated with Aβ(42) accumulation in an animal model of Niemann-Pick Type C disease

(2010) Ching-Ching Chua et al.   JOURNAL OF NEUROCHEMISTRY

Glycosylation and Sialylation of Macrophage-derived Human Apolipoprotein E Analyzed by SDS-PAGE and Mass Spectrometry

(2010) Youra Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

Macrophage Plasticity in Experimental Atherosclerosis

(2010) Jamila Khallou-Laschet et al.   PLoS One

APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure

(2009) Lynn M. Bekris et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Role of adipocyte-derived apoE in modulating adipocyte size, lipid metabolism, and gene expression in vivo

(2009) Zhi Hua Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cyclosporin A Decreases Apolipoprotein E Secretion from Human Macrophages via a Protein Phosphatase 2B-dependent and ATP-binding Cassette Transporter A1 (ABCA1)-independent Pathway

(2009) Maaike Kockx et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enrichment of glycopeptides for glycan structure and attachment site identification

(2009) Jonas Nilsson et al.   NATURE METHODS

Differential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in mice

(2008) J M Arbones-Mainar et al.   INTERNATIONAL JOURNAL OF OBESITY

ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo

(2008) Braydon L. Burgess et al.   JOURNAL OF LIPID RESEARCH

Intron-3 Retention/Splicing Controls Neuronal Expression of Apolipoprotein E in the CNS

(2008) Q. Xu et al.   JOURNAL OF NEUROSCIENCE

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON

Macrophage-derived apolipoprotein E ameliorates dyslipidemia and atherosclerosis in obese apolipoprotein E-deficient mice

(2007) Robin D. Atkinson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM