Caffeic Acid Supplement Alleviates Colonic Inflammation and Oxidative Stress Potentially Through Improved Gut Microbiota Community in Mice

Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats

(2021) M. Gui Xie et al.   Oxidative Medicine and Cellular Longevity

Glycine Attenuates Citrobacter rodentium ‐Induced Colitis by Regulating ATF6‐Mediated Endoplasmic Reticulum Stress in Mice

(2021) Yunchang Zhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Main active components of Jiawei Gegen Qinlian decoction protects against ulcerative colitis under different dietary environments in a gut microbiota-dependent manner

(2021) Qinmei Li et al.   PHARMACOLOGICAL RESEARCH

Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1

(2021) Ameng Shi et al.   Frontiers in Pharmacology

Aging Increases the Severity of Colitis and the Related Changes to the Gut Barrier and Gut Microbiota in Humans and Mice

(2020) Ailing Liu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Camellia sinensis and Litsea coreana Ameliorate Intestinal Inflammation and Modulate Gut Microbiota in Dextran Sulfate Sodium‐Induced Colitis Mice

(2020) Yan Liu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8+ T cells in mice

(2020) Lijuan Wang et al.   GUT

Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin

(2020) Ruth X. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review article: bugs, inflammation and mood-a microbiota-based approach to psychiatric symptoms in inflammatory bowel diseases

(2020) Anne K. Thomann et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Dietary Quercetin Alleviated DSS-induced Colitis in Mice through Several Possible Pathways by Transcriptome Analysis

(2020) Yuanyang Dong et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

High-Throughput Screen Identifies Host and Microbiota Regulators of Intestinal Barrier Function

(2020) Inna Grosheva et al.   GASTROENTEROLOGY

Oxidative Stress and Redox-Modulating Therapeutics in Inflammatory Bowel Disease

(2020) Arno R. Bourgonje et al.   TRENDS IN MOLECULAR MEDICINE

Geniposide attenuates dextran sulfate sodium-induced colitis in mice via Nrf-2/HO-1/NF-κB pathway

(2020) Huiju Yang et al.   Annals of Palliative Medicine

Review article: how the intestinal microbiota may reflect disease activity and influence therapeutic outcome in inflammatory bowel disease

(2020) Clara Caenepeel et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Exploring the effects of phenolic compounds to reduce intestinal damage and improve the intestinal barrier integrity: Systematic review of in vivo animal studies

(2020) Berner Andrée Sandoval-Ramírez et al.   CLINICAL NUTRITION

Sesamol Supplementation Attenuates DSS-Induced Colitis via Mediating Gut Barrier Integrity, Inflammatory Responses, and Reshaping Gut Microbiome

(2020) Beita Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Canna x generalis L.H. Bailey rhizome extract ameliorates dextran sulfate sodium-induced colitis via modulating intestinal mucosal dysfunction, oxidative stress, inflammation, and TLR4/ NF-ҡB and NLRP3 inflammasome pathways

(2020) Toka N. Mahmoud et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chlorogenic Acid Ameliorates Colitis and Alters Colonic Microbiota in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis

(2019) Peng Zhang et al.   Frontiers in Physiology

Amaranth’s 2-Caffeoylisocitric Acid—An Anti-Inflammatory Caffeic Acid Derivative That Impairs NF-κB Signaling in LPS-Challenged RAW 264.7 Macrophages

(2019) David Schröter et al.   Nutrients

Phytochemicals and inflammatory bowel disease: a review

(2019) Imam Hossen et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Protective Effects of Tyrosol Against DSS-Induced Ulcerative Colitis in Rats

(2019) Mehmet Güvenç et al.   INFLAMMATION

Modulation of gut microbiota by Ilex kudingcha improves dextran sulfate sodium-induced colitis

(2019) Peng Wan et al.   FOOD RESEARCH INTERNATIONAL

Cecropin A Alleviates Inflammation Through Modulating the Gut Microbiota of C57BL/6 Mice With DSS-Induced IBD

(2019) Zhenya Zhai et al.   Frontiers in Microbiology

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

(2019) Kaio Murilo Monteiro Espíndola et al.   Frontiers in Oncology

Inflammatory cytokines: from discoveries to therapies in IBD

(2019) Irene Marafini et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Honey Polyphenols Ameliorate DSS‐induced Ulcerative Colitis Via Modulating Gut Microbiota in Rats

(2019) Haoan Zhao et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Sesamin Enhances Nrf2-Mediated Protective Defense against Oxidative Stress and Inflammation in Colitis via AKT and ERK Activation

(2019) Xupeng Bai et al.   Oxidative Medicine and Cellular Longevity

Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice

(2019) Xiaoyuan Bian et al.   Frontiers in Microbiology

Indigo Naturalis Suppresses Colonic Oxidative Stress and Th1/Th17 Responses of DSS-Induced Colitis in Mice

(2019) Hai-tao Xiao et al.   Oxidative Medicine and Cellular Longevity

Rutaecarpine inhibits KEAP1-NRF2 interaction to activate NRF2 and ameliorate dextran sulfate sodium-induced colitis

(2019) Youbo Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of JAK2/STAT3 and NF-κB signal transduction pathways; Veronica polita alleviates dextran sulfate sodium-induced murine colitis

(2018) Md Rashedunnabi Akanda et al.   BIOMEDICINE & PHARMACOTHERAPY

Depletion of reactive oxygen species induced by chlorogenic acid triggers apoptosis-like death in Escherichia coli

(2018) Bin Lee et al.   FREE RADICAL RESEARCH

Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice

(2018) Sean R. Llewellyn et al.   GASTROENTEROLOGY

Caffeic Acid and Metformin Inhibit Invasive Phenotype Induced by TGF-β1 in C-4I and HTB-35/SiHa Human Cervical Squamous Carcinoma Cells by Acting on Different Molecular Targets

(2018) Malgorzata Tyszka-Czochara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier

(2018) Eric C. Martens et al.   NATURE REVIEWS MICROBIOLOGY

Oxidative Stress and Effect of Treatment on the Oxidation Product Decomposition Processes in IBD

(2018) Ewa Dudzińska et al.   Oxidative Medicine and Cellular Longevity

A chlorogenic acid-phospholipid complex ameliorates post-myocardial infarction inflammatory response mediated by mitochondrial reactive oxygen species in SAMP8 mice

(2018) Yi Li et al.   PHARMACOLOGICAL RESEARCH

Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling

(2018) Jiamei Ma et al.   PHYTOTHERAPY RESEARCH

Protective Effects of Salvianolic Acid A against Dextran Sodium Sulfate-Induced Acute Colitis in Rats

(2018) Kai Wang et al.   Nutrients

Linoorbitides and enterolactone mitigate inflammation-induced oxidative stress and loss of intestinal epithelial barrier integrity

(2018) Ahmed A. Almousa et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dietary chlorogenic acid supplementation affects gut morphology, antioxidant capacity and intestinal selected bacterial populations in weaned piglets

(2018) Yong Zhang et al.   Food & Function

Effect of Chlorogenic Acid Supplementation in MPTP-Intoxicated Mouse

(2018) Saumitra S. Singh et al.   Frontiers in Pharmacology

Berberis lycium Royle fruit extract mitigates oxi-inflammatory stress by suppressing NF-κB/MAPK signalling cascade in activated macrophages and Treg proliferation in splenic lymphocytes

(2018) Anamika Sharma et al.   INFLAMMOPHARMACOLOGY

Chlorogenic acids and the acyl-quinic acids: discovery, biosynthesis, bioavailability and bioactivity

(2017) Michael N. Clifford et al.   NATURAL PRODUCT REPORTS

Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies

(2017) Tian Tian et al.   Oxidative Medicine and Cellular Longevity

Gut microbiota drives the attenuation of dextran sulphate sodium-induced colitis by Huangqin decoction

(2017) Yang Yang et al.   Oncotarget

Drug development in IBD: from novel target identification to early clinical trials

(2016) Silvio Danese et al.   GUT

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis

(2016) Sathish Sivaprakasam et al.   PHARMACOLOGY & THERAPEUTICS

Chlorogenic acid enhances intestinal barrier by decreasing MLCK expression and promoting dynamic distribution of tight junction proteins in colitic rats

(2016) Zheng Ruan et al.   Journal of Functional Foods

Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice

(2016) Zhan Zhang et al.   Oncotarget

Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes

(2016) Hiroyuki Kanzaki et al.   Redox Biology

Anti-inflammatory effect of chlorogenic acid on the IL-8 production in Caco-2 cells and the dextran sulphate sodium-induced colitis symptoms in C57BL/6 mice

(2015) Hee Soon Shin et al.   FOOD CHEMISTRY

Recombinant human MFG-E8 ameliorates colon damage in DSS- and TNBS-induced colitis in mice

(2015) Yinzhong Zhang et al.   LABORATORY INVESTIGATION

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway

(2014) J Park et al.   Mucosal Immunology

Review article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases

(2014) Aleksandra Piechota-Polanczyk et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis

(2013) Martina Galatola   WORLD JOURNAL OF GASTROENTEROLOGY

Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence

(2012) Hong Zhu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Long-term Follow-up of Ulcerative Colitis in the Chinese Population

(2009) Dorothy K L Chow et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Increased CYP4B1 mRNA Is Associated with the Inhibition of Dextran Sulfate Sodium–Induced Colitis by Caffeic Acid in Mice

(2009) Zhong Ye et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Oxidative stress in ulcerative colitis-associated carcinogenesis

(2008) A. Roessner et al.   PATHOLOGY RESEARCH AND PRACTICE