A shared transcriptional code orchestrates temporal patterning of the central nervous system

Conserved genetic signatures parcellate cardinal spinal neuron classes into local and projection subsets

(2021) Peter J. Osseward et al.   SCIENCE

Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition

(2021) Matthieu X. Moreau et al.   DEVELOPMENT

Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features

(2021) Teresa Rayon et al.   DEVELOPMENT

NGN2 induces diverse neuron types from human pluripotency

(2021) Hsiu-Chuan Lin et al.   Stem Cell Reports

The nf-core framework for community-curated bioinformatics pipelines

(2020) Philip A. Ewels et al.   NATURE BIOTECHNOLOGY

An atlas of dynamic chromatin landscapes in mouse fetal development

(2020) David U. Gorkin et al.   NATURE

Transplanting neural progenitor cells to restore connectivity after spinal cord injury

(2020) Itzhak Fischer et al.   NATURE REVIEWS NEUROSCIENCE

Extrinsic activin signaling cooperates with an intrinsic temporal program to increase mushroom body neuronal diversity

(2020) Anthony M Rossi et al.   eLife

Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina

(2020) Awais Javed et al.   DEVELOPMENT

Species-specific pace of development is associated with differences in protein stability

(2020) Teresa Rayon et al.   SCIENCE

A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells

(2020) José M. Dias et al.   Science Advances

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

(2019) Katarína Tiklová et al.   Nature Communications

NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells

(2019) Jason Tchieu et al.   NATURE BIOTECHNOLOGY

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

(2019) Julien Delile et al.   DEVELOPMENT

Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes

(2019) Begüm Aydin et al.   NATURE NEUROSCIENCE

Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification

(2019) Brian S. Clark et al.   NEURON

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Principles of progenitor temporal patterning in the developing invertebrate and vertebrate nervous system

(2019) Polina Oberst et al.   CURRENT OPINION IN NEUROBIOLOGY

Establishing neuronal diversity in the spinal cord: a time and a place

(2019) Andreas Sagner et al.   DEVELOPMENT

Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord

(2019) Gauhar Masgutova et al.   Frontiers in Molecular Neuroscience

Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development

(2019) James Fraser et al.   CEREBELLUM

The Temporal Neurogenesis Patterning of Spinal p3–V3 Interneurons into Divergent Subpopulation Assemblies

(2019) Dylan Deska-Gauthier et al.   JOURNAL OF NEUROSCIENCE

Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch

(2019) Yi-Rong Peng et al.   NEURON

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

(2018) Kelly Street et al.   BMC GENOMICS

Correction: Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination (doi:10.1242/dev.106492)

(2018) Dipankar J. Dutta et al.   DEVELOPMENT

Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

(2018) Martin Häring et al.   NATURE NEUROSCIENCE

Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior

(2018) Anupama Sathyamurthy et al.   Cell Reports

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

(2018) Andreas Sagner et al.   PLOS BIOLOGY

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

(2018) Hui Hu et al.   NUCLEIC ACIDS RESEARCH

Nervous System Regionalization Entails Axial Allocation before Neural Differentiation

(2018) Vicki Metzis et al.   CELL

Subtype Diversification and Synaptic Specificity of Stem Cell-Derived Spinal Interneurons

(2018) Phuong T. Hoang et al.   NEURON

Neuronal specification in space and time

(2018) Isabel Holguera et al.   SCIENCE

A repressor-decay timer for robust temporal patterning in embryonic Drosophila neuroblast lineages

(2018) Inna Averbukh et al.   eLife

Integration of temporal and spatial patterning generates neural diversity

(2017) Ted Erclik et al.   NATURE

Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis

(2017) Stacey M Glasgow et al.   NATURE NEUROSCIENCE

Neuronal cell-type classification: challenges, opportunities and the path forward

(2017) Hongkui Zeng et al.   NATURE REVIEWS NEUROSCIENCE

The Hunchback temporal transcription factor establishes, but is not required to maintain, early-born neuronal identity

(2017) Keiko Hirono et al.   Neural Development

Fate and freedom in developing neocortical circuits

(2017) Denis Jabaudon   Nature Communications

The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development

(2017) Karolina U. Kabayiza et al.   Frontiers in Molecular Neuroscience

Bayesian Sparse Regression Analysis Documents the Diversity of Spinal Inhibitory Interneurons

(2016) Mariano I. Gabitto et al.   CELL

Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits

(2016) Jay B. Bikoff et al.   CELL

Neural Subtype Specification from Human Pluripotent Stem Cells

(2016) Yunlong Tao et al.   Cell Stem Cell

Making sense out of spinal cord somatosensory development

(2016) Helen C. Lai et al.   DEVELOPMENT

Modeling ALS with motor neurons derived from human induced pluripotent stem cells

(2016) Samuel Sances et al.   NATURE NEUROSCIENCE

CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing

(2016) Jonas Dehairs et al.   Scientific Reports

Generating Neuronal Diversity in the Mammalian Cerebral Cortex

(2015) Simona Lodato et al.   Annual Review of Cell and Developmental Biology

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

(2015) Michael J. Parsons et al.   CELL

A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors

(2015) Pierre Mattar et al.   NEURON

Intrinsically different retinal progenitor cells produce specific types of progeny

(2014) Connie Cepko   NATURE REVIEWS NEUROSCIENCE

Tgfβ Signaling Regulates Temporal Neurogenesis and Potency of Neural Stem Cells in the CNS

(2014) José M. Dias et al.   NEURON

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development

(2014) Darshan Sapkota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordination of progenitor specification and growth in mouse and chick spinal cord

(2014) A. Kicheva et al.   SCIENCE

In Vitro Generation of Neuromesodermal Progenitors Reveals Distinct Roles for Wnt Signalling in the Specification of Spinal Cord and Paraxial Mesoderm Identity

(2014) Mina Gouti et al.   PLOS BIOLOGY

The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

(2013) Jovica Ninkovic et al.   Cell Stem Cell

MicroRNA-9 promotes the switch from early-born to late-born motor neuron populations by regulating Onecut transcription factor expression

(2013) Georg Luxenhofer et al.   DEVELOPMENTAL BIOLOGY

NFIA Controls Telencephalic Progenitor Cell Differentiation through Repression of the Notch Effector Hes1

(2013) M. Piper et al.   JOURNAL OF NEUROSCIENCE

Temporal patterning of Drosophila medulla neuroblasts controls neural fates

(2013) Xin Li et al.   NATURE

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Temporal fate specification and neural progenitor competence during development

(2013) Minoree Kohwi et al.   NATURE REVIEWS NEUROSCIENCE

Hox Genes: Choreographers in Neural Development, Architects of Circuit Organization

(2013) Polyxeni Philippidou et al.   NEURON

Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification

(2012) A. Roy et al.   DEVELOPMENT

Dorsal-ventral patterning of the neural tube: A tale of three signals

(2012) Gwenvael Le Dréau et al.   Developmental Neurobiology

Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into Parkinsonian mice

(2012) Christopher R. Bye et al.   EXPERIMENTAL NEUROLOGY

Renshaw Cells and Ia Inhibitory Interneurons Are Generated at Different Times from p1 Progenitors and Differentiate Shortly after Exiting the Cell Cycle

(2012) A. Benito-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Sox9 and NFIA Coordinate a Transcriptional Regulatory Cascade during the Initiation of Gliogenesis

(2012) Peng Kang et al.   NEURON

Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program

(2011) F. J. Stam et al.   DEVELOPMENT

Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development

(2011) Qiaolin Deng et al.   DEVELOPMENT

NeuroD Factors Regulate Cell Fate and Neurite Stratification in the Developing Retina

(2011) T. J. Cherry et al.   JOURNAL OF NEUROSCIENCE

Gdf11 Facilitates Temporal Progression of Neurogenesis in the Developing Spinal Cord

(2011) Y. Shi et al.   JOURNAL OF NEUROSCIENCE

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

(2011) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental genetics of vertebrate glial–cell specification

(2010) David H. Rowitch et al.   NATURE

SOX9 induces and maintains neural stem cells

(2010) Charlotte E Scott et al.   NATURE NEUROSCIENCE

Neuronal Subtype Specification within a Lineage by Opposing Temporal Feed-Forward Loops

(2009) Magnus Baumgardt et al.   CELL

Committed Neuronal Precursors Confer Astrocytic Potential on Residual Neural Precursor Cells

(2009) Masakazu Namihira et al.   DEVELOPMENTAL CELL

Birthdays of retinal amacrine cell subtypes are systematically related to their molecular identity and soma position

(2009) P. Emanuela Voinescu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Breathing with Phox2b

(2009) V. Dubreuil et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord

(2008) Dominique Bröhl et al.   DEVELOPMENTAL BIOLOGY

Nuclear factor I gene expression in the developing forebrain

(2008) Céline Plachez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Ikaros Confers Early Temporal Competence to Mouse Retinal Progenitor Cells

(2008) Jimmy Elliott et al.   NEURON