A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells

Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes

(2019) Shabana Amanda Ali et al.   PLoS One

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex

(2019) L. Telley et al.   SCIENCE

Regulation of GLI1 by cis DNA elements and epigenetic marks

(2019) Robert Taylor et al.   DNA REPAIR

What does time mean in development?

(2018) Miki Ebisuya et al.   DEVELOPMENT

A repressor-decay timer for robust temporal patterning in embryonic Drosophila neuroblast lineages

(2018) Inna Averbukh et al.   eLife

Playing Well with Others: Extrinsic Cues Regulate Neural Progenitor Temporal Identity to Generate Neuronal Diversity

(2017) Mubarak Hussain Syed et al.   TRENDS IN GENETICS

Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells

(2016) Mayumi Okamoto et al.   Nature Communications

Generating Neuronal Diversity in the Mammalian Cerebral Cortex

(2015) Simona Lodato et al.   Annual Review of Cell and Developmental Biology

A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors

(2015) Yuichi Nishi et al.   DEVELOPMENT

Ptch2 mediates the Shh response in Ptch1-/- cells

(2014) A. C. Alfaro et al.   DEVELOPMENT

Tgfβ Signaling Regulates Temporal Neurogenesis and Potency of Neural Stem Cells in the CNS

(2014) José M. Dias et al.   NEURON

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord

(2013) K. Yu et al.   DEVELOPMENT

Titration of GLI3 Repressor Activity by Sonic Hedgehog Signaling Is Critical for Maintaining Multiple Adult Neural Stem Cell and Astrocyte Functions

(2013) R. Petrova et al.   JOURNAL OF NEUROSCIENCE

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Temporal fate specification and neural progenitor competence during development

(2013) Minoree Kohwi et al.   NATURE REVIEWS NEUROSCIENCE

Titration of Four Replication Factors Is Essential for the Xenopus laevis Midblastula Transition

(2013) C. Collart et al.   SCIENCE

Ultrasensitive response motifs: basic amplifiers in molecular signalling networks

(2013) Q. Zhang et al.   Open Biology

Mechanistic Differences in the Transcriptional Interpretation of Local and Long-Range Shh Morphogen Signaling

(2012) Tony Oosterveen et al.   DEVELOPMENTAL CELL

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

(2012) K. A. Peterson et al.   GENES & DEVELOPMENT

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development

(2011) Qiaolin Deng et al.   DEVELOPMENT

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways

(2011) F. D'Autreaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning

(2010) M. Lek et al.   DEVELOPMENT

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

(2010) E. W. Humke et al.   GENES & DEVELOPMENT

A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

(2008) S. A. Vokes et al.   GENES & DEVELOPMENT

Molecular Titration and Ultrasensitivity in Regulatory Networks

(2008) Nicolas E. Buchler et al.   JOURNAL OF MOLECULAR BIOLOGY