Renoprotective Effects of Mangiferin: Pharmacological Advances and Future Perspectives

Mangiferin as New Potential Anti-Cancer Agent and Mangiferin-Integrated Polymer Systems—A Novel Research Direction

(2021) Svetlana N. Morozkina et al.   Biomolecules

Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling

(2021) Md Jamal Uddin et al.   Antioxidants

Purification Process of Mangiferin from Mangifera indica L. Leaves and Evaluation of Its Bioactivities

(2021) Nguyen Thi Truc Loan et al.   Processes

Development of mangiferin loaded chitosan-silica hybrid scaffolds: Physicochemical and bioactivity characterization

(2021) Salita Demeyer et al.   CARBOHYDRATE POLYMERS

CO-Releasing Molecule-2 Prevents Acute Kidney Injury through Suppression of ROS-Fyn-ER Stress Signaling in Mouse Model

(2021) Md Jamal Uddin et al.   Oxidative Medicine and Cellular Longevity

Green nanotechnology of MGF-AuNPs for immunomodulatory intervention in prostate cancer therapy

(2021) Menka Khoobchandani et al.   Scientific Reports

Elicitor-mediated enhancement of biomass, polyphenols, mangiferin production and antioxidant activities in callus cultures of Salacia chinensis L.

(2021) Jaykumar J. Chavan et al.   3 Biotech

Targeting mangiferin loaded N-succinyl chitosan-alginate grafted nanoparticles against atherosclerosis – A case study against diabetes mediated hyperlipidemia in rat

(2021) Ying Wang et al.   FOOD CHEMISTRY

Oxidative Stress in the Pathophysiology of Kidney Disease: Implications for Noninvasive Monitoring and Identification of Biomarkers

(2020) Marianna Gyurászová et al.   Oxidative Medicine and Cellular Longevity

A feasible UHPLC‐MS/MS method for concurrent quantification of 10 bioactive principles in Aquilaria leaf tea by the multiple reaction monitoring analytical mode

(2020) Ping‐Chung Kuo et al.   PHYTOCHEMICAL ANALYSIS

Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway

(2020) Yanyan Song et al.   Journal of Diabetes Research

Mangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid Excretion

(2020) Xuechen Li et al.   Frontiers in Pharmacology

Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury

(2020) Md Jamal Uddin et al.   Biomolecules & Therapeutics

Anti-oxidative effect of mangiferin-chitosan nanoparticles on oxidative stress-induced renal cells

(2020) Rohini Samadarsi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Positive interaction of mangiferin with selected oral hypoglycemic drugs: a therapeutic strategy to alleviate diabetic nephropathy in experimental rats

(2020) Vidhushini Sekar et al.   MOLECULAR BIOLOGY REPORTS

Mangiferin Rich Products from Aphloia theiformis (Vahl) Benn Leaves: Extraction, Fractionation, Phytochemical Characterization, and Antioxidant Properties

(2020) Dovilė Grauzdytė et al.   MOLECULES

Phospholipid complex-loaded self-assembled phytosomal soft nanoparticles: evidence of enhanced solubility, dissolution rate, ex vivo permeability, oral bioavailability, and antioxidant potential of mangiferin

(2020) Darshan R. Telange et al.   Drug Delivery and Translational Research

Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages

(2020) Dong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Preparative scale extraction of mangiferin and lupeol from mango (Mangifera indica L.) leaves and bark by different extraction methods

(2019) Jenit Margarita Lerma-Torres et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Arachidonic Acid Metabolism and Kidney Inflammation

(2019) Tianqi Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prelusive scale extraction of mangiferin from Mangifera indica leaves: Assessing solvent competency, process optimization, kinetic study and diffusion modelling

(2019) K. Anbalagan et al.   INDUSTRIAL CROPS AND PRODUCTS

Mangiferin prevents diabetic nephropathy progression and protects podocyte function via autophagy in diabetic rat glomeruli

(2018) Xiaodan Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Preparation and mechanistic aspect of natural xanthone functionalized gold nanoparticle

(2018) Nabanita Patra et al.   Materials Science & Engineering C-Materials for Biological Applications

Mangiferin Ameliorates Cisplatin Induced Acute Kidney Injury by Upregulating Nrf-2 via the Activation of PI3K and Exhibits Synergistic Anticancer Activity With Cisplatin

(2018) Pritam Sadhukhan et al.   Frontiers in Pharmacology

Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice

(2018) Zhizhen Qin et al.   Acta Pharmaceutica Sinica B

Carbon monoxide releasing molecule-2 protects mice against acute kidney injury through inhibition of ER stress

(2018) Md Jamal Uddin et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Mangiferin attenuates cisplatin-induced acute kidney injury in rats mediating modulation of MAPK pathway

(2018) Anil Kumar Sahu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Peroxiredoxin 3 deficiency accelerates chronic kidney injury in mice through interactions between macrophages and tubular epithelial cells

(2018) Inah Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis

(2017) Guideock Kwon et al.   Oncotarget

Bio- and chemical syntheses of mangiferin and congeners

(2016) Teddy Stephen Ehianeta et al.   BIOFACTORS

Mangiferin: A xanthonoid with multipotent anti-inflammatory potential

(2016) Sukanya Saha et al.   BIOFACTORS

Mangiferin: A review of sources and interventions for biological activities

(2016) Jyotshna et al.   BIOFACTORS

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Nicholas J Kassebaum et al.   LANCET

Novel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model

(2016) Bo Yeong Jeong et al.   PLoS One

Mangiferin Inhibits Renal Urate Reabsorption by Modulating Urate Transporters in Experimental Hyperuricemia

(2015) Hua Yang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mangiferin attenuates renal ischemia-reperfusion injury by inhibiting inflammation and inducing adenosine production

(2015) Bin Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

In vitro studies on mangiferin protection against cadmium-induced human renal endothelial damage and cell death via the MAP kinase and NF-κB pathways

(2015) Peramaiyan Rajendran et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Medicinal Properties of Mangiferin, Structural Features, Derivative Synthesis, Pharmacokinetics and Biological Activities

(2015) Outhiriaradjou Benard et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Mangiferin Attenuate Sepsis-Induced Acute Kidney Injury via Antioxidant and Anti-Inflammatory Effects

(2014) Liyu He et al.   AMERICAN JOURNAL OF NEPHROLOGY

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Ultrasound-Assisted Extraction of Mangiferin from Mango (Mangifera indica L.) Leaves Using Response Surface Methodology

(2014) Tang-Bin Zou et al.   MOLECULES

Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes

(2014) Lakhmir S. Chawla et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mangiferin Attenuates Renal Fibrosis Through Down-Regulation of Osteopontin in Diabetic Rats

(2014) Xia Zhu et al.   PHYTOTHERAPY RESEARCH

Mangiferin Attenuates Diabetic Nephropathy by Inhibiting Oxidative Stress Mediated Signaling Cascade, TNFα Related and Mitochondrial Dependent Apoptotic Pathways in Streptozotocin-Induced Diabetic Rats

(2014) Pabitra Bikash Pal et al.   PLoS One

Up-regulation of glyoxalase 1 by mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats

(2013) Yao-Wu Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Extraction of mangiferin from Mangifera indica leaves using three phase partitioning coupled with ultrasound

(2013) Vrushali M. Kulkarni et al.   INDUSTRIAL CROPS AND PRODUCTS

Comparison of microwave-assisted and conventional extraction of mangiferin from mango (Mangifera indicaL.) leaves

(2013) Tangbin Zou et al.   JOURNAL OF SEPARATION SCIENCE

Soya phospholipid complex of mangiferin enhances its hepatoprotectivity by improving its bioavailability and pharmacokinetics

(2013) Sauvik Bhattacharyya et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Mangiferin – a Bioactive Xanthonoid, not only from Mango and not just Antioxidant

(2013) Adam Matkowski et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Quantification and Purification of Mangiferin from Chinese Mango (Mangifera indica L.) Cultivars and Its Protective Effect on Human Umbilical Vein Endothelial Cells under H2O2-induced Stress

(2012) Fenglei Luo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

D(+) galactosamine induced oxidative and nitrosative stress-mediated renal damage in rats via NF-κB and inducible nitric oxide synthase (iNOS) pathways is ameliorated by a polyphenol xanthone, mangiferin

(2011) Manoranjan Ghosh et al.   FREE RADICAL RESEARCH

Oxidative stress in renal dysfunction: mechanisms, clinical sequelae and therapeutic options

(2009) M P C Kao et al.   JOURNAL OF HUMAN HYPERTENSION