Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance

Effects of Quercetin on the Efficacy of Various Chemotherapeutic Drugs in Cervical Cancer Cells

(2021) Wenbin Xu et al.   Drug Design Development and Therapy

The Potential Neuroprotective Role of Free and Encapsulated Quercetin Mediated by miRNA against Neurological Diseases

(2021) Tarek Benameur et al.   Nutrients

HCV Core Protein Induces Chemokine CCL2 and CXCL10 Expression Through NF-κB Signaling Pathway in Macrophages

(2021) Xiaotian Song et al.   Frontiers in Immunology

Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus

(2021) Yi-Hung Chen et al.   Molecular Brain

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

(2020) Franc Llorens et al.   Nature Communications

Protective effect of quercetin on streptozotocin-induced diabetic peripheral neuropathy rats through modulating gut microbiota and reactive oxygen species level

(2020) Jun Xie et al.   BIOMEDICINE & PHARMACOTHERAPY

SIRT1 activation by minocycline on regulation of microglial polarization homeostasis

(2020) Ling-Hsuan Wu et al.   Aging-US

Novel Risk Factors for Progression of Diabetic and Nondiabetic CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

(2020) Amanda H. Anderson et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Metabolic alterations in Parkinson’s disease astrocytes

(2020) Tuuli-Maria Sonninen et al.   Scientific Reports

Flavones hydroxylated at 5, 7, 3′ and 4′ ameliorate skin fibrosis via inhibiting activin receptor-like kinase 5 kinase activity

(2019) Yifan Zhang et al.   Cell Death & Disease

Anti-inflammatory Property of Imperatorin on Alveolar Macrophages and Inflammatory Lung Injury

(2019) Ya-Zhen Li et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways

(2019) Boris Sabirzhanov et al.   BRAIN BEHAVIOR AND IMMUNITY

Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury

(2019) Daniel J. Hellenbrand et al.   Journal of Neuroinflammation

Lipocalin‐2: Its perspectives in brain pathology and possible roles in cognition

(2019) Kanokporn Pinyopornpanish et al.   JOURNAL OF NEUROENDOCRINOLOGY

Lipocalin-2 may produce damaging effect after cerebral ischemia by inducing astrocytes classical activation

(2019) Nan Zhao et al.   Journal of Neuroinflammation

Quercetin prevents necroptosis of oligodendrocytes by inhibiting macrophages/microglia polarization to M1 phenotype after spinal cord injury in rats

(2019) Hong Fan et al.   Journal of Neuroinflammation

The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review

(2019) Hossein Bagheri et al.   BIOFACTORS

Gut microbiota–brain axis in depression: The role of neuroinflammation

(2019) Anelise S. Carlessi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Glycyrrhizin Treatment Facilitates Extinction of Conditioned Fear Responses After a Single Prolonged Stress Exposure in Rats

(2018) Shuhua Lai et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization

(2018) Mei Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

M1/M2 macrophages in diabetic nephropathy: Nrf2/HO-1 as therapeutic targets

(2018) R. Clive Landis et al.   CURRENT PHARMACEUTICAL DESIGN

The role of mitochondria in NLRP3 inflammasome activation

(2018) Qiuyun Liu et al.   MOLECULAR IMMUNOLOGY

Safety Aspects of the Use of Quercetin as a Dietary Supplement

(2017) Susanne Andres et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Quercetin Protects Obesity-Induced Hypothalamic Inflammation by Reducing Microglia-Mediated Inflammatory Responses via HO-1 Induction

(2017) Jihyeon Yang et al.   Nutrients

TREM1 facilitates microglial phagocytosis of amyloid beta

(2016) Teng Jiang et al.   ACTA NEUROPATHOLOGICA

Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer’s Disease (AD) Brain Regions: Differential Findings in AD with and without Depression

(2016) Doortje W. Dekens et al.   JOURNAL OF ALZHEIMERS DISEASE

Balancing the immune response in the brain: IL-10 and its regulation

(2016) Diogo Lobo-Silva et al.   Journal of Neuroinflammation

Quercetin stabilizes apolipoprotein E and reduces brain Aβ levels in amyloid model mice

(2016) Xilin Zhang et al.   NEUROPHARMACOLOGY

The role of autophagy in modulation of neuroinflammation in microglia

(2016) P. Su et al.   NEUROSCIENCE

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

(2016) Hor-Yue Tan et al.   Oxidative Medicine and Cellular Longevity

Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

(2016) Lucio G. Costa et al.   Oxidative Medicine and Cellular Longevity

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

Microglial Cells as a Link between Cannabinoids and the Immune Hypothesis of Psychiatric Disorders

(2016) Sabrina F. Lisboa et al.   Frontiers in Neurology

Lipocalin-2 in the Inflammatory Activation of Brain Astrocytes

(2015) Shinrye Lee et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Reviewing the Role of Resveratrol as a Natural Modulator of Microglial Activities

(2015) Chiara Porro et al.   CURRENT PHARMACEUTICAL DESIGN

Role of quercetin as an alternative for obesity treatment: You are what you eat!

(2015) Seyed Fazel Nabavi et al.   FOOD CHEMISTRY

Selective modulation of microglia polarization to M2 phenotype for stroke treatment

(2015) Cong-Yuan Xia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of Paeonol on Anti-Neuroinflammatory Responses in Microglial Cells

(2015) Chingju Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells

(2015) Cheng-Fang Tsai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Doses of Quercetin in the Range of Serum Concentrations Exert Delipidating Effects in 3T3-L1 Preadipocytes by Acting on Different Stages of Adipogenesis, but Not in Mature Adipocytes

(2015) Itziar Eseberri et al.   Oxidative Medicine and Cellular Longevity

Diversity and plasticity of microglial cells in psychiatric and neurological disorders

(2015) Yutaka Nakagawa et al.   PHARMACOLOGY & THERAPEUTICS

Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways

(2015) Iandra Holzmann et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

From the periphery to the brain: Lipocalin-2, a friend or foe?

(2015) Ana C. Ferreira et al.   PROGRESS IN NEUROBIOLOGY

NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages

(2015) Min-gu Song et al.   PLoS One

Microglia as a critical player in both developmental and late-life CNS pathologies

(2014) Noël C. Derecki et al.   ACTA NEUROPATHOLOGICA

Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

(2014) Mi-Hyang Cho et al.   Autophagy

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

(2014) Li Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mechanisms and Potential Therapeutic Applications of Microglial Activation after Brain Injury

(2014) Jong-Youl Kim et al.   CNS Neuroscience & Therapeutics

Macrophages, Immunity, and Metabolic Disease

(2014) Joanne C. McNelis et al.   IMMUNITY

A Critical Role for Interferon Regulatory Factor 9 in Cerebral Ischemic Stroke

(2014) H.-Z. Chen et al.   JOURNAL OF NEUROSCIENCE

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

Regulatory Effects of Fisetin on Microglial Activation

(2014) Jing-Yuan Chuang et al.   MOLECULES

Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections

(2014) C M Leopold Wager et al.   Mucosal Immunology

Caspase-1/ASC Inflammasome-Mediated Activation of IL-1β–ROS–NF-κB Pathway for Control of Trypanosoma cruzi Replication and Survival Is Dispensable in NLRP3−/− Macrophages

(2014) Nilay Dey et al.   PLoS One

Effect of quercetin and rutin in some acute seizure models in mice

(2014) Dorota Nieoczym et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Lipocalin-2 Promotes M1 Macrophages Polarization in a Mouse Cardiac Ischaemia-Reperfusion Injury Model

(2014) L. Cheng et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Lipocalin-2 is involved in emotional behaviors and cognitive function

(2014) Ana Ferreira   Frontiers in Cellular Neuroscience

Dynamic Aspects of Macrophage Polarization during Atherosclerosis Progression and Regression

(2014) Michael Peled et al.   Frontiers in Immunology

Microglia actions in Alzheimer’s disease

(2013) Stefan Prokop et al.   ACTA NEUROPATHOLOGICA

The carotenoid lutein enhances matrix metalloproteinase-9 production and phagocytosis through intracellular ROS generation and ERK1/2, p38 MAPK, and RARβ activation in murine macrophages

(2013) Huey-Ming Lo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anti-neuroinflammatory Effect of a Novel Caffeamide Derivative, KS370G, in Microglial cells

(2013) Dah-Yuu Lu et al.   MOLECULAR NEUROBIOLOGY

Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways

(2013) Hsiao-Yun Lin et al.   NEUROBIOLOGY OF AGING

The Connection of Monocytes and Reactive Oxygen Species in Pain

(2013) Dagmar Hackel et al.   PLoS One

Postprandial lipoproteins and the molecular regulation of vascular homeostasis

(2013) Kathleen M. Botham et al.   PROGRESS IN LIPID RESEARCH

Targeting Heme Oxygenase-1 for Neuroprotection and Neuroinflammation in Neurodegenerative Diseases

(2012) Agnieszka Jazwa et al.   CURRENT DRUG TARGETS

CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status

(2012) H. Kitade et al.   DIABETES

Secreted protein lipocalin-2 promotes microglial M1 polarization

(2012) Eunha Jang et al.   FASEB JOURNAL

Santamarin, a sesquiterpene lactone isolated from Saussurea lappa, represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells

(2012) Hyun-Gyu Choi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice

(2012) Alexander Rodriguez Guerrero et al.   Journal of Neuroinflammation

Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game

(2012) Paqui G. Través et al.   MEDIATORS OF INFLAMMATION

Desipramine Protects Neuronal Cell Death and Induces Heme Oxygenase-1 Expression in Mes23.5 Dopaminergic Neurons

(2012) Hsiao-Yun Lin et al.   PLoS One

Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’

(2012) Guy C. Brown et al.   TRENDS IN BIOCHEMICAL SCIENCES

(+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction

(2011) Konstantin Tsoyi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation

(2011) M. Mucha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsic and Extrinsic Regulation of Innate Immune Receptors

(2011) Eunshil Jeong et al.   YONSEI MEDICAL JOURNAL

Effects of sappanchalcone on the cytoprotection and anti-inflammation via heme oxygenase-1 in human pulp and periodontal ligament cells

(2010) Gil-Saeng Jeong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Peptidoglycan enhances proinflammatory cytokine expression through the TLR2 receptor, MyD88, phosphatidylinositol 3-kinase/AKT and NF-kappaB pathways in BV-2 microglia

(2010) Hsiao-Yun Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Amitriptyline Suppresses Neuroinflammation-dependent Interleukin-10-p38 Mitogen-activated Protein Kinase-Heme Oxygenase-1 Signaling Pathway in Chronic Morphine-infused Rats

(2009) Yueh-Hua Tai et al.   ANESTHESIOLOGY

Role of sestrin2 in peroxide signaling in macrophages

(2009) Silke Essler et al.   FEBS LETTERS

The role of chemokines in the recruitment of lymphocytes to the liver

(2009) Ye H. Oo et al.   JOURNAL OF AUTOIMMUNITY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

The influence of microglia on the pathogenesis of Parkinson's disease

(2009) Caitríona M. Long-Smith et al.   PROGRESS IN NEUROBIOLOGY

Debris clearance by microglia: an essential link between degeneration and regeneration

(2008) H. Neumann et al.   BRAIN

Suppression of lipopolysaccharide-induced of inducible nitric oxide synthase and cyclooxygenase-2 by Sanguis Draconis, a dragon's blood resin, in RAW 264.7 cells

(2007) Cheuk-Sing Choy et al.   JOURNAL OF ETHNOPHARMACOLOGY