Secreted protein lipocalin-2 promotes microglial M1 polarization

 -Glucan Activates Microglia without Inducing Cytokine Production in Dectin-1-Dependent Manner

(2014) V. B. Shah et al.   JOURNAL OF IMMUNOLOGY

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia

(2012) Jörg Scheffel et al.   GLIA

Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis

(2012) Jennifer L. Berard et al.   GLIA

Lipocalin-type Prostaglandin D2Synthase Protein Regulates Glial Cell Migration and Morphology through Myristoylated Alanine-rich C-Kinase Substrate

(2012) Shinrye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipocalin-2 Is a Chemokine Inducer in the Central Nervous System

(2011) Shinrye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration

(2011) Jacque PK Ip et al.   Journal of Neuroinflammation

Lipocalin 2 Plays an Immunomodulatory Role and Has Detrimental Effects after Spinal Cord Injury

(2011) K. I. Rathore et al.   JOURNAL OF NEUROSCIENCE

Increased plasma levels of lipocalin 2 in mild cognitive impairment

(2011) Jihye Choi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

(2010) Konstantin Dirscherl et al.   Journal of Neuroinflammation

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD

Lipocalin-2: pro- or anti-apoptotic?

(2009) James P. Kehrer   CELL BIOLOGY AND TOXICOLOGY

Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-β

(2009) Alessandro Michelucci et al.   JOURNAL OF NEUROIMMUNOLOGY

Lipocalin-2 Is an Autocrine Mediator of Reactive Astrocytosis

(2009) S. Lee et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Lipocalin 2 promotes breast cancer progression

(2009) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR3 and TLR4 are innate antiviral immune receptors in human microglia: Role of IRF3 in modulating antiviral and inflammatory response in the CNS

(2009) Hyeon-Sook Suh et al.   VIROLOGY

Neutrophil Gelatinase–Associated Lipocalin (NGAL) as a Marker of Kidney Damage

(2008) Davide Bolignano et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

The brain expression of genes involved in inflammatory response, the ribosome and learning and memory is altered by centrally injected lipopolysaccharide in mice

(2008) R H Bonow et al.   PHARMACOGENOMICS JOURNAL

Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications

(2008) Joseph El Khoury et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Genetic deletion or pharmacological inhibition of cyclooxygenase-1 attenuate lipopolysaccharide-induced inflammatory response and brain injury

(2007) Sang-Ho Choi et al.   FASEB JOURNAL