TREM1 facilitates microglial phagocytosis of amyloid beta

IL12/23 p40 Inhibition Ameliorates Alzheimer's Disease-Associated Neuropathology and Spatial Memory in SAMP8 Mice

(2018) Meng-Shan Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

Peripheral monocytes are functionally altered and invade the CNS in ALS patients

(2016) Lisa Zondler et al.   ACTA NEUROPATHOLOGICA

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

A Missense Variant in TREML2 Reduces Risk of Alzheimer’s Disease in a Han Chinese Population

(2016) Teng Jiang et al.   MOLECULAR NEUROBIOLOGY

TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice

(2016) Teng Jiang et al.   MOLECULAR NEUROBIOLOGY

TREM2 modifies microglial phenotype and provides neuroprotection in P301S tau transgenic mice

(2016) Teng Jiang et al.   NEUROPHARMACOLOGY

Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes

(2015) Corinna Bliederhaeuser et al.   ACTA NEUROPATHOLOGICA

ATREM1variant alters the accumulation of Alzheimer-related amyloid pathology

(2015) Joseph M. Replogle et al.   ANNALS OF NEUROLOGY

Silencing Triggering Receptors Expressed on Myeloid Cells-1 Impaired the Inflammatory Response to Oxidized Low-Density Lipoprotein in Macrophages

(2015) Houxuan Li et al.   INFLAMMATION

CD33 modulates TREM2: convergence of Alzheimer loci

(2015) Gail Chan et al.   NATURE NEUROSCIENCE

Silencing of TREM2 exacerbates tau pathology, neurodegenerative changes, and spatial learning deficits in P301S tau transgenic mice

(2015) Teng Jiang et al.   NEUROBIOLOGY OF AGING

Pathways to Alzheimer's disease

(2014) J. Hardy et al.   JOURNAL OF INTERNAL MEDICINE

Microglia receptors and their implications in the response to amyloid β for Alzheimer’s disease pathogenesis

(2014) Deborah Doens et al.   Journal of Neuroinflammation

Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia

(2014) Tijmen J Hommes et al.   JOURNAL OF PATHOLOGY

Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

(2014) Teng Jiang et al.   NEUROPSYCHOPHARMACOLOGY

Epidemiology and Etiology of Alzheimer’s disease: From Genetic to Non- Genetic Factors

(2013) Teng Jiang et al.   Current Alzheimer Research

Triggering receptor expressed on myeloid cells 2 variant is rare in late-onset Alzheimer's disease in Han Chinese individuals

(2013) Jin-Tai Yu et al.   NEUROBIOLOGY OF AGING

Missense variant in TREML2 protects against Alzheimer's disease

(2013) Bruno A. Benitez et al.   NEUROBIOLOGY OF AGING

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Microglia during development and aging

(2013) G. Jean Harry   PHARMACOLOGY & THERAPEUTICS

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

A sandwich enzyme-linked immunosorbent assay for the quantification of insoluble membrane and scaffold proteins

(2010) Constanze Geumann et al.   ANALYTICAL BIOCHEMISTRY

Dual Induction of TREM2 and Tolerance-Related Transcript, Tmem176b, in Amyloid Transgenic Mice: Implications for Vaccine-Based Therapies for Alzheimer's Disease

(2010) Benoit Melchior et al.   ASN Neuro

The role and therapeutic potential of monocytic cells in Alzheimer's disease

(2010) Tarja Malm et al.   GLIA

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Signal Regulatory Protein-β1

(2009) Sadanand Gaikwad et al.   AMERICAN JOURNAL OF PATHOLOGY

Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis

(2009) Yousuke Murakami et al.   ARTHRITIS AND RHEUMATISM

Comparison of gene expression profiles between human and mouse monocyte subsets

(2009) M. A. Ingersoll et al.   BLOOD

Age-related alterations in innate immune receptor expression and ability of macrophages to respond to pathogen challenge in vitro

(2009) Shuang Liang et al.   MECHANISMS OF AGEING AND DEVELOPMENT