Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated review
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Title
Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated review
Authors
Keywords
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Journal
REVIEWS IN MEDICAL VIROLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-12-27
DOI
10.1002/rmv.2321
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Note: Only part of the references are listed.- New insights into the organization and regulation of the apical polarity network in mammalian epithelial cells
- (2021) Eleanor Martin et al. FEBS Journal
- SARS-CoV-2 infects cells following viral entry via clathrin-mediated endocytosis
- (2021) Armin Bayati et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tmprss2 specific miRNAs as promising regulators for SARS-CoV-2 entry checkpoint
- (2021) Taruneet Kaur et al. VIRUS RESEARCH
- Group I p21-activated kinases in leukemia cell adhesion to fibronectin
- (2021) Kateřina Kuželová et al. Cell Adhesion & Migration
- SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site
- (2021) Anna Z Mykytyn et al. eLife
- Reviews on Biological Activity, Clinical Trial and Synthesis Progress of Small Molecules for the Treatment of COVID-19
- (2021) Dingzhong Li et al. Topics in Current Chemistry
- Par‐3 family proteins in cell polarity & adhesion
- (2021) Barry J. Thompson FEBS Journal
- Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2
- (2021) Yinghui Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants
- (2021) Kui K. Chan et al. Science Advances
- Multifunctional angiotensin converting enzyme 2, the SARS-CoV-2 entry receptor, and critical appraisal of its role in acute lung injury
- (2021) Murat Oz et al. BIOMEDICINE & PHARMACOTHERAPY
- Induced dysregulation of ACE2 by SARS-CoV-2 plays a key role in COVID-19 severity
- (2021) Maryam Eskandari Mehrabadi et al. BIOMEDICINE & PHARMACOTHERAPY
- A study on non-synonymous mutational patterns in structural proteins of SARS-CoV-2
- (2021) Jayanta Kumar Das et al. GENOME
- Coronavirus infection: An immunologists' perspective
- (2021) Juan Bautista De Sanctis et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Angiotensin II-Induced Cardiac Effects Are Modulated by Endocannabinoid-Mediated CB1 Receptor Activation
- (2021) Zsuzsanna Miklós et al. Cells
- Secreted Expression of mRNA‐Encoded Truncated ACE2 Variants for SARS‐CoV‐2 via Lipid‐Like Nanoassemblies
- (2021) Min Li et al. ADVANCED MATERIALS
- Evolutionary insights into the furin cleavage sites of SARS-CoV-2 variants from humans and animals
- (2021) Abdou Nagy et al. ARCHIVES OF VIROLOGY
- Progress in the therapeutic inhibition of Cdc42 signalling
- (2021) Natasha P. Murphy et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Multilevel systems biology analysis of lung transcriptomics data identifies key miRNAs and potential miRNA target genes for SARS-CoV-2 infection
- (2021) Babajan Banaganapalli et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Decrypting the role of predicted SARS-CoV-2 miRNAs in COVID-19 pathogenesis: A bioinformatics approach
- (2021) Motiur Rahaman et al. COMPUTERS IN BIOLOGY AND MEDICINE
- In Silico and In Vitro Analyses Validate Human MicroRNAs Targeting the SARS-CoV-2 3′-UTR
- (2021) María Asunción Barreda-Manso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The lethal internal face of the coronaviruses: Kidney tropism of the SARS , MERS , and COVID 19 viruses
- (2021) Roza Motavalli et al. IUBMB LIFE
- Nanotherapeutics for treating coronavirus diseases
- (2021) Thennakoon M. Sampath U. Gunathilake et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Keep out! SARS-CoV-2 entry inhibitors: their role and utility as COVID-19 therapeutics
- (2021) Lennox Chitsike et al. Virology Journal
- Comparative Study of SARS-CoV-2, SARS-CoV-1, MERS-CoV, HCoV-229E and Influenza Host Gene Expression in Asthma: Importance of Sex, Disease Severity, and Epithelial Heterogeneity
- (2021) Mackenzie E. Coden et al. Viruses-Basel
- Exploring the therapeutic potential of forkhead box O for outfoxing COVID-19
- (2021) Pradeep Singh Cheema et al. Open Biology
- Molecular PET/CT Profiling of ACE2 Expression In Vivo: Implications for Infection and Outcome from SARS‐CoV‐2
- (2021) Hua Zhu et al. Advanced Science
- The Fight against COVID-19 on the Multi-Protease Front and Surroundings: Could an Early Therapeutic Approach with Repositioning Drugs Prevent the Disease Severity?
- (2021) Annamaria Vianello et al. Biomedicines
- Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection
- (2021) Thomas L. Williams et al. Communications Biology
- Pulmonary Aerosolized Formulation or Nasal Drops containing Recombinant Human Angiotensin converting Enzyme 2 (rhACE2) as a Potential Therapy against COVID-19
- (2021) Amjad Ayoub et al. Research Journal of Pharmacy and Technology
- Cell entry by SARS-CoV-2
- (2021) Ruchao Peng et al. TRENDS IN BIOCHEMICAL SCIENCES
- Compounds with therapeutic potential against novel respiratory 2019 coronavirus
- (2020) Miguel Angel Martinez ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The potential actions of angiotensin‐converting enzyme II (ACE2) activator diminazene aceturate (DIZE) in various diseases
- (2020) Tawar Qaradakhi et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Recent Research Advances in Renin-Angiotensin-Aldosterone System Receptors
- (2020) Kengo Azushima et al. CURRENT HYPERTENSION REPORTS
- Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
- (2020) Haibo Zhang et al. INTENSIVE CARE MEDICINE
- circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway
- (2020) Yinjie Su et al. Molecular Cancer
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- Coronavirus puts drug repurposing on the fast track
- (2020) Charlotte Harrison NATURE BIOTECHNOLOGY
- First Case of 2019 Novel Coronavirus in the United States
- (2020) Michelle L. Holshue et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
- (2020) Michael Letko et al. Nature Microbiology
- An update on ACE2 amplification and its therapeutic potential
- (2020) Alonso Marquez et al. Acta Physiologica
- Extracellular vesicles as drug delivery systems: Why and how?
- (2020) Omnia M. Elsharkasy et al. ADVANCED DRUG DELIVERY REVIEWS
- The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
- (2020) B. Coutard et al. ANTIVIRAL RESEARCH
- Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses
- (2020) Furong Qi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Plasma microRNA expression levels in HIV-1-positive patients receiving antiretroviral therapy
- (2020) Jazmin Marquez-Pedroza et al. BIOSCIENCE REPORTS
- A hypothesis for pathobiology and treatment of COVID‐19 : The centrality of ACE1 / ACE2 imbalance
- (2020) Krishna Sriram et al. BRITISH JOURNAL OF PHARMACOLOGY
- Non-coding RNA therapeutics for cardiac regeneration
- (2020) Luca Braga et al. CARDIOVASCULAR RESEARCH
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
- (2020) Carly G.K. Ziegler et al. CELL
- Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
- (2020) Vanessa Monteil et al. CELL
- Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
- (2020) Alexandra C. Walls et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- COVID-19: a new challenge for human beings
- (2020) Penghui Yang et al. Cellular & Molecular Immunology
- Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
- (2020) Wanbo Tai et al. Cellular & Molecular Immunology
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System
- (2020) Mahmoud Gheblawi et al. CIRCULATION RESEARCH
- Mesenchymal Stem Cell–Derived Extracellular Vesicles Alleviate Acute Lung Injury Via Transfer of miR-27a-3p
- (2020) Jiangmei Wang et al. CRITICAL CARE MEDICINE
- The pivotal link between ACE2 deficiency and SARS-CoV-2 infection
- (2020) Paolo Verdecchia et al. European Journal of Internal Medicine
- Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis
- (2020) Xiu-wu Pan et al. INTENSIVE CARE MEDICINE
- Novel Coronavirus COVID-19
- (2020) Christopher Vannabouathong et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Human neutralizing antibodies elicited by SARS-CoV-2 infection
- (2020) Bin Ju et al. NATURE
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- The proximal origin of SARS-CoV-2
- (2020) Kristian G. Andersen et al. NATURE MEDICINE
- RNA delivery by extracellular vesicles in mammalian cells and its applications
- (2020) Killian O’Brien et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
- (2020) Muthiah Vaduganathan et al. NEW ENGLAND JOURNAL OF MEDICINE
- MicroRNA-27a-3p aggravates renal ischemia/reperfusion injury by promoting oxidative stress via targeting growth factor receptor-bound protein 2
- (2020) X.-R. Zhao et al. PHARMACOLOGICAL RESEARCH
- Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
- (2020) Shutoku Matsuyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?
- (2020) Li Xiao et al. Viruses-Basel
- Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
- (2020) Xiuyuan Ou et al. Nature Communications
- Antihypertensive drugs and risk of COVID-19? – Authors' reply
- (2020) Lei Fang et al. Lancet Respiratory Medicine
- Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
- (2020) Lei Fang et al. Lancet Respiratory Medicine
- Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
- (2020) Cynthia Liu et al. ACS Central Science
- CD40L Reverse Signaling Influences Dendrite Spine Morphology and Expression of PSD-95 and Rho Small GTPases
- (2020) Paulina Carriba et al. Frontiers in Cell and Developmental Biology
- Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies
- (2020) Georgia Ragia et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting
- (2020) Ali Hosseini Rad SM et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Approach to the mechanism of action of hydroxychloroquine on SARS-CoV-2: a molecular docking study
- (2020) Ismail Celı̇k et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Molecules in pathogenesis: angiotensin converting enzyme 2 (ACE2)
- (2020) Owen Wiese et al. JOURNAL OF CLINICAL PATHOLOGY
- Broad and differential animal ACE2 receptor usage by SARS-CoV-2
- (2020) Xuesen Zhao et al. JOURNAL OF VIROLOGY
- The characterization of extracellular vesicles-derived microRNAs in Thai malaria patients
- (2020) Nutpakal Ketprasit et al. MALARIA JOURNAL
- Extrapulmonary manifestations of COVID-19
- (2020) Aakriti Gupta et al. NATURE MEDICINE
- Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2
- (2020) Stepan Nersisyan et al. PLoS One
- ACE2 and COVID-19 and the resulting ARDS
- (2020) Xiaoqing Zhang et al. POSTGRADUATE MEDICAL JOURNAL
- COVID-19: A promising cure for the global panic
- (2020) Balachandar Vellingiri et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Fruitful neutralizing antibody pipeline brings hope to defeat SARS-Cov-2
- (2020) Alex Renn et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy
- (2020) Mina K. Chung et al. EBioMedicine
- Discovery and characterization of ACE2 – a 20-year journey of surprises from vasopeptidase to COVID-19
- (2020) Nigel M. Hooper et al. CLINICAL SCIENCE
- An in-silico approach to study the possible interactions of miRNA between human and SARS-CoV2
- (2020) Abhijit Sarma et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- COVID-19 update: The race to therapeutic development
- (2020) Julianne D. Twomey et al. DRUG RESISTANCE UPDATES
- COVID-19: fighting the invisible enemy with microRNAs
- (2020) Neeraj Chauhan et al. Expert Review of Anti-Infective Therapy
- ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases
- (2020) Ravindra K. Sharma et al. HYPERTENSION
- T cell responses and therapies against SARS‐CoV‐2 infection
- (2020) Salman M. Toor et al. IMMUNOLOGY
- Design of novel viral attachment inhibitors of the spike glycoprotein (S) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) through virtual screening and dynamics
- (2020) Arafat Rahman Oany et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Targeted therapy strategies against SARS-CoV-2 cell entry mechanisms: A systematic review of in vitro and in vivo studies
- (2020) Simin Seyedpour et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The ACE2 as a “rescue protein” or “suspect enzyme” in COVID-19: possible application of the “engineered inactive hrsACE2” as a safer therapeutic agent in the treatment of SARS-CoV-2 infection
- (2020) Reza Khodarahmi et al. Journal of the Iranian Chemical Society
- Plasma ACE2 and risk of death or cardiometabolic diseases: a case-cohort analysis
- (2020) Sukrit Narula et al. LANCET
- Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
- (2020) Anum Glasgow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and functional modelling of SARS-CoV-2 entry in animal models
- (2020) Greg N. Brooke et al. Scientific Reports
- Coronavirus disease 2019: A tissue engineering and regenerative medicine perspective
- (2020) Abbas Shafiee et al. Stem Cells Translational Medicine
- Human recombinant soluble ACE2 in severe COVID-19
- (2020) Alexander Zoufaly et al. Lancet Respiratory Medicine
- ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives
- (2020) Federica Saponaro et al. Frontiers in Molecular Biosciences
- Identification of Novel Hypothalamic MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating ACE2 and TMPRSS2 Expression: An In Silico Analysis
- (2020) Debasmita Mukhopadhyay et al. Brain Sciences
- Targeting ACE2 for COVID-19 Therapy: Opportunities and Challenges
- (2020) Hongpeng Jia et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics
- (2020) Nurit Haspel et al. BIOPHYSICAL JOURNAL
- Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection
- (2020) Vanessa Monteil et al. EMBO Molecular Medicine
- Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)
- (2020) Chaima Mouffouk et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Neutralizing antibodies targeting SARS-CoV-2 spike protein
- (2020) Shi Xiaojie et al. Stem Cell Research
- An effective drug against COVID-19: reality or dream?
- (2020) Atieh Yaghoubi et al. Expert Review of Respiratory Medicine
- ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors
- (2020) Zofia Wicik et al. Journal of Clinical Medicine
- Beta- and Novel Delta-Coronaviruses Are Identified from Wild Animals in the Qinghai-Tibetan Plateau, China
- (2020) Wentao Zhu et al. VIROLOGICA SINICA
- Neutralizing antibodies for the treatment of COVID-19
- (2020) Shibo Jiang et al. Nature Biomedical Engineering
- The antiviral effects of human microRNA miR-302c-3p against hepatitis B virus infection
- (2019) Susumu Hamada-Tsutsumi et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Human Coronavirus: Host-Pathogen Interaction
- (2019) To Sing Fung et al. Annual Review of Microbiology
- Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness
- (2019) Jason W. Dang et al. Cell Reports
- miRDB: an online database for prediction of functional microRNA targets
- (2019) Yuhao Chen et al. NUCLEIC ACIDS RESEARCH
- Endoplasmic reticulum rather than mitochondria plays a major role in the neuronal apoptosis induced by polybrominated diphenyl ether-153
- (2019) Xin Li et al. TOXICOLOGY LETTERS
- MicroRNA delivery through nanoparticles
- (2019) Sharon Wei Ling Lee et al. JOURNAL OF CONTROLLED RELEASE
- Breaking the convention: Sialoglycan variants, Co-receptors and Alternative Receptors for Influenza A Virus Entry
- (2019) Umut Karakus et al. JOURNAL OF VIROLOGY
- New insights into apical-basal polarization in epithelia
- (2019) Amalia Riga et al. CURRENT OPINION IN CELL BIOLOGY
- MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages
- (2019) Kazuki Yamada et al. GENE
- Metazoan MicroRNAs
- (2018) David P. Bartel CELL
- A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension
- (2018) Anna R. Hemnes et al. EUROPEAN RESPIRATORY JOURNAL
- Regulating Cdc42 and Its Signaling Pathways in Cancer: Small Molecules and MicroRNA as New Treatment Candidates
- (2018) Xing-Hua Xiao et al. MOLECULES
- MiR-124 aggravates failing hearts by suppressing CD151-facilitated angiogenesis in heart
- (2018) Yanru Zhao et al. Oncotarget
- Actin blobs prefigure dendrite branching sites
- (2018) Vanitha Nithianandam et al. JOURNAL OF CELL BIOLOGY
- miRNA-205 Nanoformulation Sensitizes Prostate Cancer Cells to Chemotherapy
- (2018) Prashanth Nagesh et al. Cancers
- Theoretical tool bridging cell polarities with development of robust morphologies
- (2018) Silas Boye Nissen et al. eLife
- miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions
- (2017) Chih-Hung Chou et al. NUCLEIC ACIDS RESEARCH
- DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions
- (2017) Dimitra Karagkouni et al. NUCLEIC ACIDS RESEARCH
- MERS, SARS and other coronaviruses as causes of pneumonia
- (2017) Yudong Yin et al. RESPIROLOGY
- CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts
- (2017) Chun-Mei Tang et al. Scientific Reports
- Restitution of Tumor Suppressor MicroRNA-145 Using Magnetic Nanoformulation for Pancreatic Cancer Therapy
- (2016) Saini Setua et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Cdc42: Role in Cancer Management
- (2015) Muhammad Imran Qadir et al. Chemical Biology & Drug Design
- Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis
- (2015) Jean Kaoru Millet et al. VIRUS RESEARCH
- Angiotensin-converting enzyme 2 is subject to post-transcriptional regulation bymiR-421
- (2014) Daniel W. Lambert et al. CLINICAL SCIENCE
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
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