- Home
- Publications
- Publication Search
- Publication Details
Title
Resolving inflammation by TAM receptor activation
Authors
Keywords
Anti-inflammation, Resolution of inflammation, TAM receptors, Gas6, Pros1, Efferocytosis
Journal
PHARMACOLOGY & THERAPEUTICS
Volume 227, Issue -, Pages 107893
Publisher
Elsevier BV
Online
2021-05-13
DOI
10.1016/j.pharmthera.2021.107893
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells
- (2021) Shuai Wang et al. CELL RESEARCH
- Growth Arrest-Specific Gene 6 Administration Ameliorates Sepsis-Induced Organ Damage in Mice and Reduces ROS Formation In Vitro
- (2021) Livia Salmi et al. Cells
- A Pro-resolving Role for Galectin-1 in Acute Inflammation
- (2020) Hannah L. Law et al. Frontiers in Pharmacology
- Transcriptomic Analysis of Monocyte-Derived Non-Phagocytic Macrophages Favors a Role in Limiting Tissue Repair and Fibrosis
- (2020) Sergei Butenko et al. Frontiers in Immunology
- Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis
- (2020) Stefano Alivernini et al. NATURE MEDICINE
- Glucocorticoid-induced leucine zipper modulates macrophage polarization and apoptotic cell clearance
- (2020) Juliana P. Vago et al. PHARMACOLOGICAL RESEARCH
- Blame the signaling: Role of cAMP for the resolution of inflammation
- (2020) Luciana P. Tavares et al. PHARMACOLOGICAL RESEARCH
- Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis
- (2020) Julia Vullings et al. Journal of Immunology Research
- Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism
- (2019) Yannick Degboé et al. Frontiers in Immunology
- Mediators of the Resolution of the Inflammatory Response
- (2019) Michelle A. Sugimoto et al. TRENDS IN IMMUNOLOGY
- The Pros1/Tyro3 axis protects against periodontitis by modulating STAT/SOCS signalling
- (2019) Lei Jiang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Gas6/Axl signaling attenuates alveolar inflammation in ischemia-reperfusion-induced acute lung injury by up-regulating SOCS3-mediated pathway
- (2019) Chung-Kan Peng et al. PLoS One
- STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation
- (2019) Saroj Nepal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gas6 Attenuates Sepsis-Induced Tight Junction Injury and Vascular Endothelial Hyperpermeability via the Axl/NF-κB Signaling Pathway
- (2019) Jingjing Ni et al. Frontiers in Pharmacology
- Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes
- (2019) Juliana P. Vago et al. Frontiers in Immunology
- TAM receptors, Phosphatidylserine, inflammation, and Cancer
- (2019) Tal Burstyn-Cohen et al. Cell Communication and Signaling
- Resolvin D1 promotes efferocytosis in aging by limiting senescent cell‐induced MerTK cleavage
- (2019) Nicholas Rymut et al. FASEB JOURNAL
- AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications
- (2019) Chenjing Zhu et al. Molecular Cancer
- Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors
- (2018) Gail Otulakowski et al. ANESTHESIOLOGY
- Autophagy balances inflammation in innate immunity
- (2018) Vojo Deretic et al. Autophagy
- Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers
- (2018) Aleksander M Grabiec et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response
- (2018) Eric Ubil et al. JOURNAL OF CLINICAL INVESTIGATION
- Maresins: Specialized Proresolving Lipid Mediators and Their Potential Role in Inflammatory-Related Diseases
- (2018) Shi Tang et al. MEDIATORS OF INFLAMMATION
- Antiphospholipid Antibodies Inhibit Trophoblast Toll-Like Receptor and Inflammasome Negative Regulators
- (2018) Melissa J. Mulla et al. Arthritis & Rheumatology
- Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models
- (2018) Claire E. J. Waterborg et al. Frontiers in Immunology
- Macrophage-Derived Protein S Facilitates Apoptotic Polymorphonuclear Cell Clearance by Resolution Phase Macrophages and Supports Their Reprogramming
- (2018) Delphine Lumbroso et al. Frontiers in Immunology
- Angiotensin-(1–7) Promotes Resolution of Eosinophilic Inflammation in an Experimental Model of Asthma
- (2018) Giselle S. Magalhaes et al. Frontiers in Immunology
- Antibody Cross-Linking of CD14 Activates MerTK and Promotes Human Macrophage Clearance of Apoptotic Neutrophils: the Dual Role of CD14 at the Crossroads Between M1 and M2c Polarization
- (2018) Gaetano Zizzo et al. INFLAMMATION
- Resolution of chronic inflammatory disease: universal and tissue-specific concepts
- (2018) Georg Schett et al. Nature Communications
- Plasticity of antimicrobial and phagocytic programs in human macrophages
- (2018) Dennis Montoya et al. IMMUNOLOGY
- Lysyl-tRNA synthetase–expressing colon spheroids induce M2 macrophage polarization to promote metastasis
- (2018) Seo Hee Nam et al. JOURNAL OF CLINICAL INVESTIGATION
- DEL-1 promotes macrophage efferocytosis and clearance of inflammation
- (2018) Ioannis Kourtzelis et al. NATURE IMMUNOLOGY
- The level of synovial AXL expression determines the outcome of inflammatory arthritis, possibly depending on the upstream role of TGF-β1
- (2018) Claire E J Waterborg et al. RHEUMATOLOGY
- MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
- (2017) Evangelos Triantafyllou et al. GUT
- MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis
- (2017) Bishuang Cai et al. JOURNAL OF CLINICAL INVESTIGATION
- Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation
- (2017) Sarah N. Cross et al. JOURNAL OF IMMUNOLOGY
- Galectin-1: A Jack-of-All-Trades in the Resolution of Acute and Chronic Inflammation
- (2017) Victoria Sundblad et al. JOURNAL OF IMMUNOLOGY
- Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors
- (2017) Nan Chiang et al. MOLECULAR ASPECTS OF MEDICINE
- New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration
- (2017) Charles N. Serhan et al. MOLECULAR ASPECTS OF MEDICINE
- Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells
- (2017) Lidia Bosurgi et al. SCIENCE
- Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies
- (2017) Marie Schoumacher et al. Current Oncology Reports
- Angiotensin-(1-7) Promotes Resolution of Neutrophilic Inflammation in a Model of Antigen-Induced Arthritis in Mice
- (2017) Lívia C. Barroso et al. Frontiers in Immunology
- Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice
- (2016) Jihye Han et al. Autophagy
- Inflammasome Complexes: Emerging Mechanisms and Effector Functions
- (2016) Vijay A.K. Rathinam et al. CELL
- Exogenous Gas6 attenuates silica-induced inflammation on differentiated THP-1 macrophages
- (2016) Yan Shen et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Mer receptor tyrosine kinase negatively regulates lipoteichoic acid-induced inflammatory response via PI3K/Akt and SOCS3
- (2016) Bing Zhang et al. MOLECULAR IMMUNOLOGY
- MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
- (2016) Bishuang Cai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plasminogen is a critical regulator of cutaneous wound healing
- (2016) R. Sulniute et al. THROMBOSIS AND HAEMOSTASIS
- Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance
- (2016) Michelle Amantéa Sugimoto et al. Journal of Immunology Research
- Resolution of Inflammation: What Controls Its Onset?
- (2016) Michelle A. Sugimoto et al. Frontiers in Immunology
- TAM Receptor Signaling in Immune Homeostasis
- (2015) Carla V. Rothlin et al. Annual Review of Immunology
- Protective Effects of Growth Arrest-Specific Protein 6 (Gas6) on Sepsis-Induced Acute Kidney Injury
- (2015) Long-wang Chen et al. INFLAMMATION
- The association of Tyro3/Axl/Mer signaling with inflammatory response, disease activity in patients with primary Sjögren's syndrome
- (2015) Baodong Qin et al. JOINT BONE SPINE
- Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation
- (2015) Simon McArthur et al. JOURNAL OF IMMUNOLOGY
- The Role and Effects of Glucocorticoid-Induced Leucine Zipper in the Context of Inflammation Resolution
- (2015) Juliana P. Vago et al. JOURNAL OF IMMUNOLOGY
- TAM Receptor–Dependent Regulation of SOCS3 and MAPKs Contributes to Proinflammatory Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages
- (2015) Shasha Zheng et al. JOURNAL OF IMMUNOLOGY
- Growth arrest–specific protein 6 protects against renal ischemia–reperfusion injury
- (2015) Matthew D. Giangola et al. JOURNAL OF SURGICAL RESEARCH
- The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung
- (2015) T Fujimori et al. Mucosal Immunology
- Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation
- (2015) Ji-Yeon Choi et al. Science Signaling
- Gaseous mediators in resolution of inflammation
- (2015) John L. Wallace et al. SEMINARS IN IMMUNOLOGY
- ACTH: The forgotten therapy
- (2015) Trinidad Montero-Melendez SEMINARS IN IMMUNOLOGY
- Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation
- (2015) Mauro Perretti et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation
- (2015) Ji-Yeon Choi et al. Science Signaling
- TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis
- (2014) J. H. M. van der Meer et al. BLOOD
- Diminished soluble levels of growth arrest specific protein 6 and tyrosine kinase receptor Axl in patients with rheumatoid arthritis
- (2014) Iman H. Bassyouni et al. International Journal of Rheumatic Diseases
- Receptor Tyrosine Kinases, TYRO3, AXL, and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-induced Activation
- (2014) Wen-I Tsou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma
- (2014) T. Shibata et al. JOURNAL OF IMMUNOLOGY
- Plasmin Induces In Vivo Monocyte Recruitment through Protease-Activated Receptor-1–, MEK/ERK-, and CCR2-Mediated Signaling
- (2014) Aline A. F. Carmo et al. JOURNAL OF IMMUNOLOGY
- Role of Phosphatidylserine Receptors in Enveloped Virus Infection
- (2014) K. Morizono et al. JOURNAL OF VIROLOGY
- Diversification of TAM receptor tyrosine kinase function
- (2014) Anna Zagórska et al. NATURE IMMUNOLOGY
- The value of glucocorticoid co-therapy in different rheumatic diseases - positive and adverse effects
- (2014) Marlies C van der Goes et al. ARTHRITIS RESEARCH & THERAPY
- Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities
- (2014) Erin D Lew et al. eLife
- Changes in macrophage phenotype as the immune response evolves
- (2013) Julia Lichtnekert et al. CURRENT OPINION IN PHARMACOLOGY
- Plasticity of Leukocytic Exudates in Resolving Acute Inflammation Is Regulated by MicroRNA and Proresolving Mediators
- (2013) Yongsheng Li et al. IMMUNITY
- Growth Arrest–Specific Protein 6 Attenuates Neutrophil Migration and Acute Lung Injury in Sepsis
- (2013) Matthew D. Giangola et al. SHOCK
- Biology of the TAM Receptors
- (2013) G. Lemke Cold Spring Harbor Perspectives in Biology
- Therapeutic efficacy of Tyro3, Axl, and Mer tyrosine kinase agonists in collagen-induced arthritis
- (2012) B. T. van den Brand et al. ARTHRITIS AND RHEUMATISM
- Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction
- (2012) G. Zizzo et al. JOURNAL OF IMMUNOLOGY
- Macrophage plasticity and polarization in tissue repair and remodelling
- (2012) Alberto Mantovani et al. JOURNAL OF PATHOLOGY
- In Vitro Generation of Monocyte-Derived Macrophages under Serum-Free Conditions Improves Their Tumor Promoting Functions
- (2012) Flora Rey-Giraud et al. PLoS One
- New Lives Given by Cell Death: Macrophage Differentiation Following Their Encounter with Apoptotic Leukocytes during the Resolution of Inflammation
- (2012) Amiram Ariel et al. Frontiers in Immunology
- Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages
- (2011) Tingting Deng et al. IMMUNOLOGY
- Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)
- (2011) Edward Thorp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus
- (2011) C. Ekman et al. RHEUMATOLOGY
- Disturbances of apoptotic cell clearance in systemic lupus erythematosus
- (2011) Wen-Hai Shao et al. ARTHRITIS RESEARCH & THERAPY
- Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis
- (2011) Jun Wu et al. ARTHRITIS RESEARCH & THERAPY
- Managing the adverse effects of nonsteroidal anti-inflammatory drugs
- (2011) Paola Patrignani et al. Expert Review of Clinical Pharmacology
- Modulation of Macrophage Efferocytosis in Inflammation
- (2011) Darlynn Korns et al. Frontiers in Immunology
- Nonresolving Inflammation
- (2010) Carl Nathan et al. CELL
- Inflammation 2010: New Adventures of an Old Flame
- (2010) Ruslan Medzhitov CELL
- Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids
- (2010) Sagie Schif-Zuck et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury
- (2010) Laura Llacuna et al. HEPATOLOGY
- Targeting granulocyte apoptosis: mechanisms, models, and therapies
- (2010) Rodger Duffin et al. IMMUNOLOGICAL REVIEWS
- Lipopolysaccharide inhibits macrophage phagocytosis of apoptotic neutrophils by regulating the production of tumour necrosis factor α and growth arrest-specific gene 6
- (2010) Xueying Feng et al. IMMUNOLOGY
- Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood
- (2010) C. EKMAN et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages
- (2009) A. McColl et al. JOURNAL OF IMMUNOLOGY
- Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP
- (2008) J. Bystrom et al. BLOOD
- Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-α
- (2008) Sylwia Michlewska et al. FASEB JOURNAL
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now