Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Macrophage autophagy protects against liver fibrosis in mice

(2015) Jasper Lodder et al.   Autophagy

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

(2015) Kun Liu et al.   Autophagy

Hepatic inflammation and fibrosis: Functional links and key pathways

(2015) Ekihiro Seki et al.   HEPATOLOGY

Fibrosis — A Common Pathway to Organ Injury and Failure

(2015) Don C. Rockey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Altered L-type Ca2+ channel activity contributes to exacerbated hypoperfusion and mortality in smooth muscle cell BK channel-deficient septic mice

(2014) Hui Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy

(2014) Chul-Su Yang et al.   Autophagy

iASPP is a novel autophagy inhibitor in keratinocytes

(2014) A. Chikh et al.   JOURNAL OF CELL SCIENCE

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2013) Kairui Mao et al.   CELL RESEARCH

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

The receptor tyrosine kinase Axl in cancer: Biological functions and therapeutic implications

(2013) Juliano D. Paccez et al.   INTERNATIONAL JOURNAL OF CANCER

The Nlrp3 inflammasome regulates acute graft-versus-host disease

(2013) Dragana Jankovic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Histones Activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury

(2013) H. Huang et al.   JOURNAL OF IMMUNOLOGY

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice

(2011) Agnès Fourcot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress

(2011) Yongke Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Growth arrest-specific protein 6 is hepatoprotective against murine ischemia/reperfusion injury

(2010) Laura Llacuna et al.   HEPATOLOGY

Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function

(2010) Leif E. Sander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-10 inhibits the starvation induced autophagy in macrophages via class I phosphatidylinositol 3-kinase (PI3K) pathway

(2010) Hun-Jung Park et al.   MOLECULAR IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

The phospholipase D1 pathway modulates macroautophagy

(2010) Claudia Dall'Armi et al.   Nature Communications

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

Fibrin accumulation plays a critical role in the sensitization to lipopolysaccharide-induced liver injury caused by ethanol in mice

(2009) Juliane I. Beier et al.   HEPATOLOGY

Inflammasomes: too big to miss

(2009) Andrea Stutz et al.   JOURNAL OF CLINICAL INVESTIGATION

Growth arrest-specific protein 6 deficiency impairs liver tissue repair after acute toxic hepatitis in mice

(2009) Fouad Lafdil et al.   JOURNAL OF HEPATOLOGY

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE