Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke

Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

(2021) Qing‐zhang Tuo et al.   MEDICINAL RESEARCH REVIEWS

Immune responses to stroke: mechanisms, modulation, and therapeutic potential

(2020) Costantino Iadecola et al.   JOURNAL OF CLINICAL INVESTIGATION

Ferroptosis and Its Potential Role in Human Diseases

(2020) Chu Han et al.   Frontiers in Pharmacology

Defective mitophagy in Alzheimer’s disease

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The potential LXRβ agonist stigmasterol protects against hypoxia/reoxygenation injury by modulating mitophagy in primary hippocampal neurons

(2020) Md. Nazmul Haque et al.   PHYTOMEDICINE

A new role of glutathione peroxidase 4 during human erythroblast enucleation

(2020) Hakim Ouled-Haddou et al.   Blood Advances

NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms

(2019) Naiara Santana-Codina et al.   HAEMATOLOGICA

Effects of rapamycin on social interaction deficits and gene expression in mice exposed to valproic acid in utero

(2019) Hiroko Kotajima-Murakami et al.   Molecular Brain

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Breaking the chains: deubiquitylating enzyme specificity begets function

(2019) Michael J. Clague et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

(2019) Yang Li et al.   CELL DEATH AND DIFFERENTIATION

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Liproxstatin-1 Attenuates Morphine Tolerance through Inhibiting Spinal Ferroptosis-like Cell Death

(2019) Xuhui Chen et al.   ACS Chemical Neuroscience

Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury

(2019) Lianjiu Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cylindromatosis mediates neuronal cell death in vitro and in vivo

(2018) Goutham K. Ganjam et al.   CELL DEATH AND DIFFERENTIATION

Cell Death Mechanisms in Stroke and Novel Molecular and Cellular Treatment Options

(2018) Emine Sekerdag et al.   Current Neuropharmacology

Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis

(2018) Anja Jelinek et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy in ischemic stroke

(2018) Pei Wang et al.   PROGRESS IN NEUROBIOLOGY

A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury

(2018) Marta Koch et al.   Frontiers in Cellular Neuroscience

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

(2018) Zili Zhang et al.   Autophagy

Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1

(2018) Yan Li et al.   Autophagy

Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases

(2018) Mingzhu Tang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ferroptosis, a Recent Defined Form of Critical Cell Death in Neurological Disorders

(2018) Jia-rui Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

(2018) Barry Boland et al.   NATURE REVIEWS DRUG DISCOVERY

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

Design and Methodology of a Pilot Randomized Controlled Trial of Transcranial Direct Current Stimulation in Acute Middle Cerebral Artery Stroke (STICA)

(2018) Estelle Pruvost-Robieux et al.   Frontiers in Neurology

Cytosolic iron chaperones: Proteins delivering iron cofactors in the cytosol of mammalian cells

(2017) Caroline C. Philpott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

(2017) Q-z Tuo et al.   MOLECULAR PSYCHIATRY

Deubiquitylating enzymes and drug discovery: emerging opportunities

(2017) Jeanine A. Harrigan et al.   NATURE REVIEWS DRUG DISCOVERY

The Copper bis(thiosemicarbazone) Complex CuII(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu

(2017) Mikko T. Huuskonen et al.   Neurotherapeutics

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

(2017) Omkar Zilka et al.   ACS Central Science

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy

(2016) Chao Lin et al.   JOURNAL OF PINEAL RESEARCH

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Reperfusion injury and reactive oxygen species: The evolution of a concept

(2015) D. Neil Granger et al.   Redox Biology

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

(2014) Rui Sheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bex2 Controls Proliferation of Human Glioblastoma Cells Through NF-κB Signaling Pathway

(2014) Qingming Meng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes

(2014) Gorica Ristic et al.   Frontiers in Molecular Neuroscience

Role of the ubiquitin–proteasome system in brain ischemia: Friend or foe?

(2013) Margarida V. Caldeira et al.   PROGRESS IN NEUROBIOLOGY

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity

(2012) Alexandra Kollara et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Central administration of pan-somatostatin agonist ODT8-SST prevents abdominal surgery-induced inhibition of circulating ghrelin, food intake and gastric emptying in rats

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