A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury

An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK

(2016) Yan Hao et al.   eLife

HECT-type E3 ubiquitin ligases in nerve cell development and synapse physiology

(2015) Mateusz Cyryl Ambrozkiewicz et al.   FEBS LETTERS

Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury

(2015) Vera Valakh et al.   NEUROBIOLOGY OF DISEASE

Injury-Induced Decline of Intrinsic Regenerative Ability Revealed by Quantitative Proteomics

(2015) Stephane Belin et al.   NEURON

Subtype-Specific Regeneration of Retinal Ganglion Cells following Axotomy: Effects of Osteopontin and mTOR Signaling

(2015) Xin Duan et al.   NEURON

Extrinsic and intrinsic regulation of axon regeneration at a crossroads

(2015) Andrew Kaplan et al.   Frontiers in Molecular Neuroscience

Mutations in USP9X Are Associated with X-Linked Intellectual Disability and Disrupt Neuronal Cell Migration and Growth

(2014) Claire C. Homan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Insulin/IGF1 Signaling Inhibits Age-Dependent Axon Regeneration

(2014) Alexandra B. Byrne et al.   NEURON

Cell-intrinsic requirement of Dscam1 isoform diversity for axon collateral formation

(2014) H. He et al.   SCIENCE

Dscam Expression Levels Determine Presynaptic Arbor Sizes in Drosophila Sensory Neurons

(2013) Jung Hwan Kim et al.   NEURON

Loss of Usp9x Disrupts Cortical Architecture, Hippocampal Development and TGFβ-Mediated Axonogenesis

(2013) Shane Stegeman et al.   PLoS One

DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury

(2013) T. A. Watkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Axon Degeneration and Regeneration: Insights from Drosophila Models of Nerve Injury

(2012) Yanshan Fang et al.   Annual Review of Cell and Developmental Biology

A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity

(2012) Yanshan Fang et al.   CURRENT BIOLOGY

Axon Regrowth during Development and Regeneration Following Injury Share Molecular Mechanisms

(2012) Shiri P. Yaniv et al.   CURRENT BIOLOGY

c-Jun N-terminal Kinase 1 (JNK1) Is Required for Coordination of Netrin Signaling in Axon Guidance

(2012) Chao Qu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade

(2012) Chun Li et al.   NATURE NEUROSCIENCE

Notch Signaling Inhibits Axon Regeneration

(2012) Rachid El Bejjani et al.   NEURON

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

Kruppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

(2012) M. G. Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Intrinsic Mechanisms of Axon Regeneration

(2011) Kai Liu et al.   Annual Review of Neuroscience

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

(2011) Fang Sun et al.   NATURE

Axon Regeneration Pathways Identified by Systematic Genetic Screening in C. elegans

(2011) Lizhen Chen et al.   NEURON

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways

(2011) P. Nix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Glial Regenerative Response to Central Nervous System Injury Is Enabled by Pros-Notch and Pros-NFκB Feedback

(2011) Kentaro Kato et al.   PLOS BIOLOGY

MAG and OMgp Synergize with Nogo-A to Restrict Axonal Growth and Neurological Recovery after Spinal Cord Trauma

(2010) W. B. J. Cafferty et al.   JOURNAL OF NEUROSCIENCE

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Assessing Spinal Axon Regeneration and Sprouting in Nogo-, MAG-, and OMgp-Deficient Mice

(2010) Jae K. Lee et al.   NEURON

Impaired regenerative response of primary sensory neurons in ZPK/DLK gene-trap mice

(2009) Aki Itoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The DLK-1 Kinase Promotes mRNA Stability and Local Translation in C. elegans Synapses and Axon Regeneration

(2009) Dong Yan et al.   CELL

KLF Family Members Regulate Intrinsic Axon Regeneration Ability

(2009) D. L. Moore et al.   SCIENCE

Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans

(2008) C. V. Gabel et al.   DEVELOPMENT

Axonal Injury and Regeneration in the Adult Brain of Drosophila

(2008) D. Ayaz et al.   JOURNAL OF NEUROSCIENCE