Effects of rapamycin on social interaction deficits and gene expression in mice exposed to valproic acid in utero

Dendritic spine anomalies and PTEN alterations in a mouse model of VPA-induced autism spectrum disorder

(2018) Usman Mahmood et al.   PHARMACOLOGICAL RESEARCH

Late effect of developmental exposure to glycidol on hippocampal neurogenesis in mice: Loss of parvalbumin-expressing interneurons

(2017) Masashi Kawashima et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

PI3K/AKT/mTOR-mediated autophagy in the development of autism spectrum disorder

(2016) Jun Zhang et al.   BRAIN RESEARCH BULLETIN

Randomized controlled trial of vitamin D supplementation in children with autism spectrum disorder

(2016) Khaled Saad et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Valproic acid exposure sequentially activates Wnt and mTOR pathways in rats

(2016) Liyan Qin et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation

(2016) Takuya Kawanai et al.   NEUROCHEMICAL RESEARCH

Everolimus improves neuropsychiatric symptoms in a patient with tuberous sclerosis carrying a novel TSC2 mutation

(2016) Su-Kyeong Hwang et al.   Molecular Brain

Increased expression of the PI3K catalytic subunit p110δ underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family

(2016) Ashwini C. Poopal et al.   Molecular Autism

From molecules to neural morphology: understanding neuroinflammation in autism spectrum condition

(2016) Adam M. H. Young et al.   Molecular Autism

Thromboxane A2 stimulates neurite outgrowth in cerebral cortical neurons via mitogen activated protein kinase signaling

(2015) Satoko Sumimoto et al.   BRAIN RESEARCH

Suppression of NMDA receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors

(2015) Jaeseung Kang et al.   Frontiers in Molecular Neuroscience

Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid

(2015) Chiara Nicolini et al.   Acta Neuropathologica Communications

Exploring the Validity of Valproic Acid Animal Model of Autism

(2015) Darine Froy N. Mabunga et al.   Experimental Neurobiology

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

(2014) Andrei I Molosh et al.   NATURE NEUROSCIENCE

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

The Role of Target of Rapamycin Signaling Networks in Plant Growth and Metabolism

(2014) Y. Xiong et al.   PLANT PHYSIOLOGY

In Utero Exposure to Valproic Acid Changes Sleep in Juvenile Rats: A Model for Sleep Disturbances in Autism

(2014) Danielle M. Cusmano et al.   SLEEP

Spinal muscular atrophy: An update on therapeutic progress

(2013) Joonbae Seo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sex differences in autism spectrum disorders

(2013) Donna M. Werling et al.   CURRENT OPINION IN NEUROLOGY

Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

(2013) Jakob Christensen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Signaling by Fyn-ADAP via the Carma1–Bcl-10–MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells

(2013) Kamalakannan Rajasekaran et al.   NATURE IMMUNOLOGY

mTOR complexes in neurodevelopmental and neuropsychiatric disorders

(2013) Mauro Costa-Mattioli et al.   NATURE NEUROSCIENCE

Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis

(2013) Helen S. Bateup et al.   NEURON

Glycidol Induces Axonopathy by Adult-Stage Exposure and Aberration of Hippocampal Neurogenesis Affecting Late-Stage Differentiation by Developmental Exposure in Rats

(2013) Hirotoshi Akane et al.   TOXICOLOGICAL SCIENCES

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Rapamycin reverses impaired social interaction in mouse models of tuberous sclerosis complex

(2012) Atsushi Sato et al.   Nature Communications

Prevalence of Autism Spectrum Disorders in a Total Population Sample

(2011) Young Shin Kim et al.   AMERICAN JOURNAL OF PSYCHIATRY

Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid

(2011) Shunsuke Kataoka et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The Quantitative Nature of Autistic Social Impairment

(2011) JOHN N. CONSTANTINO   PEDIATRIC RESEARCH

Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling

(2010) Thomas S. Lisse et al.   FASEB JOURNAL

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Valproic Acid Activates the PI3K/Akt/mTOR Pathway in Muscle and Ameliorates Pathology in a Mouse Model of Duchenne Muscular Dystrophy

(2009) Praveen B. Gurpur et al.   AMERICAN JOURNAL OF PATHOLOGY

Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice

(2009) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

Cytokines and CNS Development

(2009) Benjamin E. Deverman et al.   NEURON

Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice

(2009) E. Kolozsi et al.   NEUROSCIENCE

Haploinsufficiency forPtenandSerotonin transportercooperatively influences brain size and social behavior

(2009) Damon T. Page et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE