Reexamining assumptions about miRNA-guided gene silencing

How Naunyn-Schmiedeberg’s Archives of Pharmacology deals with fraudulent papers from paper mills

(2021) Roland Seifert   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Risks of miRNA Therapeutics: In a Drug Target Perspective

(2021) Song Zhang et al.   Drug Design Development and Therapy

Is transcriptional regulation just going through a phase?

(2021) Geeta J. Narlikar et al.   MOLECULAR CELL

Antisense technology: an overview and prospectus

(2021) Stanley T. Crooke et al.   NATURE REVIEWS DRUG DISCOVERY

A quantitative map of human primary microRNA processing sites

(2021) Kijun Kim et al.   MOLECULAR CELL

Structural basis for piRNA targeting

(2021) Todd A. Anzelon et al.   NATURE

Noncoding RNA therapeutics — challenges and potential solutions

(2021) Melanie Winkle et al.   NATURE REVIEWS DRUG DISCOVERY

Comparison of Long-term Ambulatory Function in Patients with Duchenne Muscular Dystrophy Treated with Eteplirsen and Matched Natural History Controls

(2021) Jerry R. Mendell et al.   Journal of Neuromuscular Diseases

Emerging Oligonucleotide Therapeutics for Rare Neuromuscular Diseases

(2021) Yoshitsugu Aoki et al.   Journal of Neuromuscular Diseases

Digital magic, or the dark arts of the 21 st century—how can journals and peer reviewers detect manuscripts and publications from paper mills?

(2020) Jennifer A. Byrne et al.   FEBS LETTERS

The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy

(2020) Annemieke Aartsma-Rus et al.   Nucleic Acid Therapeutics

Structural Basis for pri-miRNA Recognition by Drosha

(2020) Wenxing Jin et al.   MOLECULAR CELL

Retraction Note: miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2

(2020) Jing Y. Krzeszinski et al.   NATURE

mRNA structural dynamics shape Argonaute-target interactions

(2020) Suzan Ruijtenberg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRNA dilution during oocyte growth disables the microRNA pathway in mammalian oocytes

(2020) Shubhangini Kataruka et al.   NUCLEIC ACIDS RESEARCH

The biochemical basis for the cooperative action of microRNAs

(2020) Daniel Briskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antisense Drugs Make Sense for Neurological Diseases

(2020) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Functional Atlas of Primary miRNA Maturation by the Microprocessor

(2020) Greggory M. Rice et al.   MOLECULAR CELL

FANTOM enters 20th year: expansion of transcriptomic atlases and functional annotation of non-coding RNAs

(2020) Imad Abugessaisa et al.   NUCLEIC ACIDS RESEARCH

Validation of human microRNA target pathways enables evaluation of target prediction tools

(2020) Fabian Kern et al.   NUCLEIC ACIDS RESEARCH

Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs

(2019) Keith T. Gagnon et al.   Nucleic Acid Therapeutics

An estimate of the total number of true human miRNAs

(2019) Julia Alles et al.   NUCLEIC ACIDS RESEARCH

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Regulation of gene expression by miR-144/451 during mouse erythropoiesis

(2019) Peng Xu et al.   BLOOD

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences

(2019) David T. McSwiggen et al.   GENES & DEVELOPMENT

The biochemical basis of microRNA targeting efficacy

(2019) Sean E. McGeary et al.   SCIENCE

Phase Transitions in the Assembly and Function of Human miRISC

(2018) Jessica Sheu-Gruttadauria et al.   CELL

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Regulation of microRNA biogenesis and its crosstalk with other cellular pathways

(2018) Thomas Treiber et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel class of microRNA-recognition elements that function only within open reading frames

(2018) Kai Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Genome-wide Mapping of DROSHA Cleavage Sites on Primary MicroRNAs and Noncanonical Substrates

(2017) Baekgyu Kim et al.   MOLECULAR CELL

Multivalent Recruitment of Human Argonaute by GW182

(2017) Elad Elkayam et al.   MOLECULAR CELL

An integrated expression atlas of miRNAs and their promoters in human and mouse

(2017) Derek de Rie et al.   NATURE BIOTECHNOLOGY

A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencing

(2017) Mathieu N. Flamand et al.   NUCLEIC ACIDS RESEARCH

Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs

(2017) Xiulong Shen et al.   NUCLEIC ACIDS RESEARCH

Distribution of miRNA expression across human tissues

(2016) Nicole Ludwig et al.   NUCLEIC ACIDS RESEARCH

Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122

(2016) Peter Sarnow et al.   Annual Review of Virology

Argonaute Family Protein Expression in Normal Tissue and Cancer Entities

(2016) Daniel Völler et al.   PLoS One

Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides

(2015) William E. Salomon et al.   CELL

A Dynamic Search Process Underlies MicroRNA Targeting

(2015) Stanley D. Chandradoss et al.   CELL

Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA

(2015) Chen Davidovich et al.   MOLECULAR CELL

miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity

(2015) Michael J. Moore et al.   Nature Communications

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

With Reference to Reference Genes: A Systematic Review of Endogenous Controls in Gene Expression Studies

(2015) Joanne R. Chapman et al.   PLoS One

Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance

(2014) Rémy Denzler et al.   MOLECULAR CELL

Competitive Endogenous RNAs Cannot Alter MicroRNA Function In Vivo

(2014) Jennifer A. Broderick et al.   MOLECULAR CELL

Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition

(2014) Andrew D. Bosson et al.   MOLECULAR CELL

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

Poly(A)-tail profiling reveals an embryonic switch in translational control

(2014) Alexander O. Subtelny et al.   NATURE

miR-CLIP capture of a miRNA targetome uncovers a lincRNA H19–miR-106a interaction

(2014) Jochen Imig et al.   Nature Chemical Biology

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

(2014) Daniel J. Hogan et al.   PLoS One

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments

(2013) J. F. Huggett et al.   CLINICAL CHEMISTRY

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Argonaute Divides Its RNA Guide into Domains with Distinct Functions and RNA-Binding Properties

(2012) Liang Meng Wee et al.   CELL

Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting

(2012) Gabriel B. Loeb et al.   MOLECULAR CELL

Expression determinants of mammalian argonaute proteins in mediating gene silencing

(2012) Paul N. Valdmanis et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

(2011) David M Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects

(2011) S. Petri et al.   RNA

Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing

(2011) J. A. Broderick et al.   RNA

Allele-Selective Inhibition of Huntingtin Expression by Switching to an miRNA-like RNAi Mechanism

(2010) Jiaxin Hu et al.   CHEMISTRY & BIOLOGY

Target mRNA abundance dilutes microRNA and siRNA activity

(2010) Aaron Arvey et al.   Molecular Systems Biology

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Functional Dissection of the Human TNRC6 (GW182-Related) Family of Proteins

(2009) D. Baillat et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

(2009) K. Takimoto et al.   RNA

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

miR-122, a paradigm for the role of microRNAs in the liver

(2008) Muriel Girard et al.   JOURNAL OF HEPATOLOGY

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE